Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT05865 , Small conductance calcium-activated potassium channel protein 2
 Protein Info 
Gene Name KCNN2
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q9H2S1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT05865
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0375052
 Compound Info 
N-(4-methylpyridin-2-yl)-4-pyridin-2-yl-1,3-thiazol-2-amine
   Show/Hide
C14H12N4S
  2
1
IC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383396
 Compound Info 
N,4-dipyridin-2-yl-1,3-thiazol-2-amine
   Show/Hide
C13H10N4S
  2
1
IC50 = 123 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 543 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0401123
 Compound Info 
5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
   Show/Hide
C11H9ClN4S
  1
1
IC50 = 530 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388337
 Compound Info 
N-benzyl-5-chloropyrazolo[1,5-a]pyrimidin-7-amine
   Show/Hide
C13H11ClN4
  1
1
IC50 = 1100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0867692
 Compound Info 
1,1'-(1,3-phenylenebis(methylene))bis(8-isopropyl-2-methylisoquinolinium)iodide
   Show/Hide
C34H38I2N2
  1
1
Ki = 90 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0858748
 Compound Info 
1,1'-(butane-1,4-diyl)bis(8-isopropyl-2-methylisoquinolinium)iodide
   Show/Hide
C30H38I2N2
  1
1
Ki = 194 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0851749
 Compound Info 
1,1'-(1,4-phenylenebis(methylene))bis(8-isopropyl-2-methylisoquinolinium)iodide
   Show/Hide
C34H38I2N2
  1
1
Ki = 397 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0916019
 Compound Info 
1,1'-(propane-1,3-diyl)bis(8-isopropyl-2-methylisoquinolinium)iodide
   Show/Hide
C29H36I2N2
  1
1
Ki = 593 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0894247
 Compound Info 
1,1'-(pentane-1,5-diyl)bis(8-isopropyl-2-methylisoquinolinium)iodide
   Show/Hide
C31H40I2N2
  1
1
Ki = 878 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS