| Compound ID |
Compound Name |
Compound Formula |
|
CP0412052
|
3-chloro-2-methyl-7-(1-oxo-2,8-diazaspiro[4.5]decan-8-yl)-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C18H17ClF3N5O
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
Ki = 82 nM
|
|
|
|
CP0852935
|
3-chloro-2-methyl-7-(2-methyl-1-oxo-2,8-diazaspiro[4.5]decan-8-yl)-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C19H19ClF3N5O
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
Ki = 530 nM
|
|
|
|
CP0852936
|
3-chloro-7-(4-hydroxypiperidin-1-yl)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C15H14ClF3N4O
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
Ki = 440 nM
|
|
|
|
CP0396537
|
4-amino-1-[3-chloro-6-cyano-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridin-7-yl]piperidine-4-carboxamide
Show/Hide
|
C16H16ClF3N6O
|
2
|
| 1 |
IC50 = 290 nM
|
|
|
| 2 |
Ki = 250 nM
|
|
|
|
CP0432155
|
3-chloro-7-[(2S)-2-(hydroxymethyl)morpholin-4-yl]-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C15H14ClF3N4O2
|
2
|
| 1 |
IC50 = 380 nM
|
|
|
| 2 |
Ki = 750 nM
|
|
|
|
CP0538749
|
3-chloro-7-[(2R)-2-(hydroxymethyl)morpholin-4-yl]-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C15H14ClF3N4O2
|
2
|
| 1 |
IC50 = 390 nM
|
|
|
| 2 |
Ki = 1300 nM
|
|
|
|
CP0875942
|
N-(4-chloro-2-(2-(3-fluorobenzylidene)hydrazinecarbonyl)phenyl)-3-((2,3-dihydroxypropylthio)methyl)benzamide
Show/Hide
|
C25H23ClFN3O4S
|
2
|
| 1 |
IC50 = 460 nM
|
|
|
| 2 |
Ki = 690 nM
|
|
|
|
CP0392939
|
2-methyl-7-(1-oxo-2,8-diazaspiro[4.5]decan-8-yl)-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C18H18F3N5O
|
2
|
| 1 |
IC50 = 1500 nM
|
|
|
| 2 |
Ki = 2000 nM
|
|
|
|
CP0411999
|
7-(4-aminopiperidin-1-yl)-3-chloro-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C15H15ClF3N5
|
2
|
| 1 |
IC50 = 2500 nM
|
|
|
| 2 |
Ki = 2300 nM
|
|
|
|
CP0412050
|
2-methyl-7-[4-(pyridin-2-ylamino)piperidin-1-yl]-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C20H19F3N6
|
2
|
| 1 |
IC50 = 6500 nM
|
|
|
| 2 |
Ki = 14000 nM
|
|
|
|
CP0865069
|
7-(1-oxo-2,8-diazaspiro[4.5]decan-8-yl)-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
Show/Hide
|
C17H16F3N5O
|
2
|
| 1 |
IC50 > 15000 nM
|
|
|
| 2 |
Ki = 10000 nM
|
|
|
|
CP0396536
|
N-(4-chlorophenyl)-5-methoxy-2-[[3-(trifluoromethyl)phenyl]sulfonylamino]benzamide
Show/Hide
|
C21H16ClF3N2O4S
|
2
|
| 1 |
IC50 > 7300 nM
|
|
|
| 2 |
Ki > 25000 nM
|
|
|
