Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT05574 , Palmitoleoyl-protein carboxylesterase NOTUM
Gene Name NOTUM
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q6P988
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT05574
 
Compound ID Compound Name Compound Formula
CP0322688
5-(4-chloro-3-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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C9H4ClF3N2O2
 2
1
EC50 = 3500 nM
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2
IC50 = 18 nM
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CP0043620
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
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C8H10N4O2
 1
1
EC50 = 45800 nM
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CP0564067
5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-ol
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C12H14N2O2
 1
1
IC50 = 0.051 nM
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CP0424689
5-(4-isopropylphenyl)-1,3,4-oxadiazol-2-ol
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C11H12N2O2
 1
1
IC50 = 0.075 nM
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CP0528364
5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazol-2-ol
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C10H11N3O2
 1
1
IC50 = 0.19 nM
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CP0528365
5-[3-(dimethylamino)phenyl]-1,3,4-oxadiazol-2-ol
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C10H11N3O2
 1
1
IC50 = 0.19 nM
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CP0424690
5-(4-cyclopropylphenyl)-1,3,4-oxadiazol-2-ol
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C11H10N2O2
 1
1
IC50 = 0.26 nM
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CP0572315
5-(3-cyclopropylphenyl)-1,3,4-oxadiazol-2-ol
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C11H10N2O2
 1
1
IC50 = 0.26 nM
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CP0556822
5-(4-ethylphenyl)-1,3,4-oxadiazol-2-ol
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C10H10N2O2
 1
1
IC50 = 0.27 nM
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CP0507438
5-(4-isopropoxyphenyl)-1,3,4-oxadiazol-2-ol
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C11H12N2O3
 1
1
IC50 = 0.35 nM
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CP0557093
5-[2-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-ol
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C9H5F3N2O2
 1
1
IC50 = 0.43 nM
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CP0507440
5-(3-ethylphenyl)-1,3,4-oxadiazol-2-ol
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C10H10N2O2
 1
1
IC50 = 0.45 nM
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CP0424801
5-(4-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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C9H5F3N2O2
 1
1
IC50 = 0.46 nM
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CP0561950
5-(3-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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C9H5F3N2O2
 1
1
IC50 = 0.78 nM
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CP0344327
2-(6-chloro-7-cyclopropylthieno[3,2-d]pyrimidin-4-yl)sulfanylacetic acid
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C11H9ClN2O2S2
 1
1
IC50 = 1.1 nM
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CP0517328
5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-ol
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C9H8N2O3
 1
1
IC50 = 1.2 nM
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CP0573241
5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-ol
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C9H8N2O3
 1
1
IC50 = 1.4 nM
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CP0161623
5-(3-chlorophenyl)-1,3,4-oxadiazol-2-ol
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C8H5ClN2O2
 1
1
IC50 = 1.8 nM
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CP0557883
5-[4-cyclopropyl-3-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-ol
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C12H9F3N2O2
 1
1
IC50 = 1.8 nM
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CP0557885
5-(4-methylphenyl)-1,3,4-oxadiazol-2-ol
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C9H8N2O2
 1
1
IC50 = 2 nM
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CP0424800
5-[3-cyclopropyl-4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-ol
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C12H9F3N2O2
 1
1
IC50 = 2.9 nM
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CP0557886
5-(3-methylphenyl)-1,3,4-oxadiazol-2-ol
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C9H8N2O2
 1
1
IC50 = 2.9 nM
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CP0424802
5-(4-(difluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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C9H6F2N2O2
 1
1
IC50 = 3 nM
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CP0573144
5-(3-(difluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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C9H6F2N2O2
 1
1
IC50 = 3.1 nM
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CP0507439
5-(4-fluorophenyl)-1,3,4-oxadiazol-2-ol
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C8H5FN2O2
 1
1
IC50 = 3.5 nM
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CP0553675
5-(2-methylphenyl)-1,3,4-oxadiazol-2-ol
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C9H8N2O2
 1
1
IC50 = 3.6 nM
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CP0137276
3-methyl-1-[2-[5-methyl-6-(trifluoromethyl)furo[2,3-d]pyrimidin-4-yl]sulfanylacetyl]imidazolidin-4-one
   Show/Hide
C14H13F3N4O3S
 1
1
IC50 = 3.9 nM
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CP0564066
5-[4-propan-2-yl-3-(trifluoromethyl)phenyl]-3H-1,3,4-oxadiazol-2-one
   Show/Hide
C12H11F3N2O2
 1
1
IC50 = 6.2 nM
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CP0330019
5-(2-chlorophenyl)-1,3,4-oxadiazol-2-ol
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C8H5ClN2O2
 1
1
IC50 = 6.7 nM
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CP0424691
5-(2-fluorophenyl)-3H-1,3,4-oxadiazol-2-one
   Show/Hide
C8H5FN2O2
 1
1
IC50 = 11 nM
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CP0301396
2-[4-chloro-3-(trifluoromethyl)phenyl]-1,3,4-oxadiazole
   Show/Hide
C9H4ClF3N2O
 1
1
IC50 = 13 nM
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CP0507441
5-(3-fluorophenyl)-1,3,4-oxadiazol-2-ol
   Show/Hide
C8H5FN2O2
 1
1
IC50 = 13 nM
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CP0560480
5-[4-(dimethylamino)-3-(trifluoromethyl)phenyl]-3H-1,3,4-oxadiazol-2-one
   Show/Hide
C11H10F3N3O2
 1
1
IC50 = 15 nM
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CP0557884
5-(4-nitrophenyl)-1,3,4-oxadiazol-2-ol
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C8H5N3O4
 1
1
IC50 = 18 nM
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CP0561949
4-(5-hydroxy-1,3,4-oxadiazol-2-yl)benzonitrile
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C9H5N3O2
 1
1
IC50 = 27 nM
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CP0558349
5-(4-methyl-3-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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C10H7F3N2O2
 1
1
IC50 = 31 nM
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CP0573143
5-[4-chloro-3-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-ol
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C9H4ClF3N2OS
 1
1
IC50 = 31 nM
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CP0466168
5-(1,4-dimethyl-1,2,3,4-tetrahydroquinoxalin-6-yl)-1,3,4-oxadiazol-2-ol
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C12H14N4O2
 1
1
IC50 = 32 nM
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CP0528363
5-(1-methylindolin-6-yl)-1,3,4-oxadiazol-2-ol
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C11H11N3O2
 1
1
IC50 = 33 nM
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CP0203300
5-phenyl-1,3,4-oxadiazol-2-ol
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C8H6N2O2
 1
1
IC50 = 41 nM
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CP0532023
N-isoquinolin-6-yl-2-(2-methylphenoxy)acetamide
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C18H16N2O2
 1
1
IC50 = 85 nM
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CP0561952
(3S)-1-[4-chloro-3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxylic acid
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C12H11ClF3NO2
 1
1
IC50 = 110 nM
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CP0408413
[7-[(4-chlorophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 2,3-dihydro-1,4-benzoxazine-4-carboxylate
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C22H21ClN4O5
 1
1
IC50 = 170 nM
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CP0558348
5-(1-methylindolin-5-yl)-1,3,4-oxadiazol-2-ol
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C11H11N3O2
 1
1
IC50 = 380 nM
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CP0495592
5-(3,4-dichlorophenyl)-1,3,4-oxadiazol-2-ol
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C8H4Cl2N2O2
 1
1
IC50 = 430 nM
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CP0560493
5-(4-chlorophenyl)-3H-1,3,4-thiadiazol-2-one
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C8H5ClN2OS
 1
1
IC50 = 940 nM
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CP0557903
5-(4-chlorophenyl)-1,2-oxazol-3-one
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C9H6ClNO2
 1
1
IC50 = 1600 nM
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CP0074615
5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ol
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C8H5ClN2O2
 1
1
IC50 = 2100 nM
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CP0424692
1-(4-chlorophenyl)triazole
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C8H6ClN3
 1
1
IC50 = 2900 nM
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CP0560495
(5-phenyl-1,2-oxazol-3-yl)methanol
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C10H9NO2
 1
1
IC50 = 4000 nM
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CP0152125
1,2,3-triazole analogue, 15
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C8H6ClN3
 1
1
IC50 = 4200 nM
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CP0546811
[1-(4-chlorophenyl)triazol-4-yl]methanol
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C9H8ClN3O
 1
1
IC50 = 11500 nM
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CP0560494
(5-phenyl-1,3,4-oxadiazol-2-yl)methanol
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C9H8N2O2
 1
1
IC50 = 14000 nM
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CP0557904
(5-phenyl-1,3-oxazol-2-yl)methanol
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C10H9NO2
 1
1
IC50 = 17000 nM
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CP0528366
(3-phenyl-1,2-oxazol-5-yl)methanol
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C10H9NO2
 1
1
IC50 = 19000 nM
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CP0574835
(5-phenyl-1,2,4-oxadiazol-3-yl)methanol
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C9H8N2O2
 1
1
IC50 = 36000 nM
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CP0560496
2-(5-fluoro-1H-indol-3-yl)ethylurea
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C11H12FN3O
 1
1
IC50 = 37200 nM
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CP0561951
[1-(4-chlorophenyl)-5-methyltriazol-4-yl]methanol
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C10H10ClN3O
 1
1
IC50 = 42000 nM
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CP0557094
(3-phenyl-1,2,4-oxadiazol-5-yl)methanol
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C9H8N2O2
 1
1
IC50 = 65000 nM
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CP0572317
1-(4-chlorophenyl)pyrazole
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C9H7ClN2
 1
1
IC50 = 69000 nM
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CP0114894
3-(4-chlorophenyl)-4H-1,2-oxazol-5-one
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C9H6ClNO2
 1
1
IC50 = 77000 nM
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CP0088261
5-(4-chlorophenyl)-2H-tetrazole
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C7H5ClN4
 1
1
IC50 > 100000 nM
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CP0330018
3-(4-chlorophenyl)-4H-1,2,4-oxadiazol-5-one
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C8H5ClN2O2
 1
1
IC50 > 100000 nM
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CP0507442
CHEMBL4743178
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C10H9ClN2O
 1
1
IC50 > 100000 nM
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CP0528367
(4-methyl-5-phenyl-1,2,4-triazol-3-yl)methanol
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C10H11N3O
 1
1
IC50 > 100000 nM
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