Compound ID |
Compound Name |
Compound Formula |
CP0322688
|
5-(4-chloro-3-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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|
C9H4ClF3N2O2
|
2
|
1 |
EC50 = 3500 nM
|
|
|
2 |
IC50 = 18 nM
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|
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CP0043620
|
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
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|
C8H10N4O2
|
1
|
1 |
EC50 = 45800 nM
|
|
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CP0564067
|
5-(4-tert-butylphenyl)-1,3,4-oxadiazol-2-ol
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C12H14N2O2
|
1
|
1 |
IC50 = 0.051 nM
|
|
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CP0424689
|
5-(4-isopropylphenyl)-1,3,4-oxadiazol-2-ol
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|
C11H12N2O2
|
1
|
1 |
IC50 = 0.075 nM
|
|
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CP0528364
|
5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazol-2-ol
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|
C10H11N3O2
|
1
|
1 |
IC50 = 0.19 nM
|
|
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CP0528365
|
5-[3-(dimethylamino)phenyl]-1,3,4-oxadiazol-2-ol
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|
C10H11N3O2
|
1
|
1 |
IC50 = 0.19 nM
|
|
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CP0424690
|
5-(4-cyclopropylphenyl)-1,3,4-oxadiazol-2-ol
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|
C11H10N2O2
|
1
|
1 |
IC50 = 0.26 nM
|
|
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CP0572315
|
5-(3-cyclopropylphenyl)-1,3,4-oxadiazol-2-ol
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|
C11H10N2O2
|
1
|
1 |
IC50 = 0.26 nM
|
|
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CP0556822
|
5-(4-ethylphenyl)-1,3,4-oxadiazol-2-ol
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|
C10H10N2O2
|
1
|
1 |
IC50 = 0.27 nM
|
|
|
CP0507438
|
5-(4-isopropoxyphenyl)-1,3,4-oxadiazol-2-ol
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|
C11H12N2O3
|
1
|
1 |
IC50 = 0.35 nM
|
|
|
CP0557093
|
5-[2-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-ol
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|
C9H5F3N2O2
|
1
|
1 |
IC50 = 0.43 nM
|
|
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CP0507440
|
5-(3-ethylphenyl)-1,3,4-oxadiazol-2-ol
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|
C10H10N2O2
|
1
|
1 |
IC50 = 0.45 nM
|
|
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CP0424801
|
5-(4-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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|
C9H5F3N2O2
|
1
|
1 |
IC50 = 0.46 nM
|
|
|
CP0561950
|
5-(3-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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|
C9H5F3N2O2
|
1
|
1 |
IC50 = 0.78 nM
|
|
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CP0344327
|
2-(6-chloro-7-cyclopropylthieno[3,2-d]pyrimidin-4-yl)sulfanylacetic acid
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|
C11H9ClN2O2S2
|
1
|
1 |
IC50 = 1.1 nM
|
|
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CP0517328
|
5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-ol
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|
C9H8N2O3
|
1
|
1 |
IC50 = 1.2 nM
|
|
|
CP0573241
|
5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-ol
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|
C9H8N2O3
|
1
|
1 |
IC50 = 1.4 nM
|
|
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CP0161623
|
5-(3-chlorophenyl)-1,3,4-oxadiazol-2-ol
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|
C8H5ClN2O2
|
1
|
1 |
IC50 = 1.8 nM
|
|
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CP0557883
|
5-[4-cyclopropyl-3-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-ol
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|
C12H9F3N2O2
|
1
|
1 |
IC50 = 1.8 nM
|
|
|
CP0557885
|
5-(4-methylphenyl)-1,3,4-oxadiazol-2-ol
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|
C9H8N2O2
|
1
|
1 |
IC50 = 2 nM
|
|
|
CP0424800
|
5-[3-cyclopropyl-4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-ol
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|
C12H9F3N2O2
|
1
|
1 |
IC50 = 2.9 nM
|
|
|
CP0557886
|
5-(3-methylphenyl)-1,3,4-oxadiazol-2-ol
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|
C9H8N2O2
|
1
|
1 |
IC50 = 2.9 nM
|
|
|
CP0424802
|
5-(4-(difluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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|
C9H6F2N2O2
|
1
|
1 |
IC50 = 3 nM
|
|
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CP0573144
|
5-(3-(difluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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|
C9H6F2N2O2
|
1
|
1 |
IC50 = 3.1 nM
|
|
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CP0507439
|
5-(4-fluorophenyl)-1,3,4-oxadiazol-2-ol
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|
C8H5FN2O2
|
1
|
1 |
IC50 = 3.5 nM
|
|
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CP0553675
|
5-(2-methylphenyl)-1,3,4-oxadiazol-2-ol
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|
C9H8N2O2
|
1
|
1 |
IC50 = 3.6 nM
|
|
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CP0137276
|
3-methyl-1-[2-[5-methyl-6-(trifluoromethyl)furo[2,3-d]pyrimidin-4-yl]sulfanylacetyl]imidazolidin-4-one
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|
C14H13F3N4O3S
|
1
|
1 |
IC50 = 3.9 nM
|
|
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CP0564066
|
5-[4-propan-2-yl-3-(trifluoromethyl)phenyl]-3H-1,3,4-oxadiazol-2-one
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|
C12H11F3N2O2
|
1
|
1 |
IC50 = 6.2 nM
|
|
|
CP0330019
|
5-(2-chlorophenyl)-1,3,4-oxadiazol-2-ol
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|
C8H5ClN2O2
|
1
|
1 |
IC50 = 6.7 nM
|
|
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CP0424691
|
5-(2-fluorophenyl)-3H-1,3,4-oxadiazol-2-one
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|
C8H5FN2O2
|
1
|
1 |
IC50 = 11 nM
|
|
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CP0301396
|
2-[4-chloro-3-(trifluoromethyl)phenyl]-1,3,4-oxadiazole
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|
C9H4ClF3N2O
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0507441
|
5-(3-fluorophenyl)-1,3,4-oxadiazol-2-ol
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|
C8H5FN2O2
|
1
|
1 |
IC50 = 13 nM
|
|
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CP0560480
|
5-[4-(dimethylamino)-3-(trifluoromethyl)phenyl]-3H-1,3,4-oxadiazol-2-one
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|
C11H10F3N3O2
|
1
|
1 |
IC50 = 15 nM
|
|
|
CP0557884
|
5-(4-nitrophenyl)-1,3,4-oxadiazol-2-ol
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|
C8H5N3O4
|
1
|
1 |
IC50 = 18 nM
|
|
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CP0561949
|
4-(5-hydroxy-1,3,4-oxadiazol-2-yl)benzonitrile
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|
C9H5N3O2
|
1
|
1 |
IC50 = 27 nM
|
|
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CP0558349
|
5-(4-methyl-3-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-ol
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|
C10H7F3N2O2
|
1
|
1 |
IC50 = 31 nM
|
|
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CP0573143
|
5-[4-chloro-3-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-ol
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|
C9H4ClF3N2OS
|
1
|
1 |
IC50 = 31 nM
|
|
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CP0466168
|
5-(1,4-dimethyl-1,2,3,4-tetrahydroquinoxalin-6-yl)-1,3,4-oxadiazol-2-ol
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|
C12H14N4O2
|
1
|
1 |
IC50 = 32 nM
|
|
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CP0528363
|
5-(1-methylindolin-6-yl)-1,3,4-oxadiazol-2-ol
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|
C11H11N3O2
|
1
|
1 |
IC50 = 33 nM
|
|
|
CP0203300
|
5-phenyl-1,3,4-oxadiazol-2-ol
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|
C8H6N2O2
|
1
|
1 |
IC50 = 41 nM
|
|
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CP0532023
|
N-isoquinolin-6-yl-2-(2-methylphenoxy)acetamide
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|
C18H16N2O2
|
1
|
1 |
IC50 = 85 nM
|
|
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CP0561952
|
(3S)-1-[4-chloro-3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxylic acid
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|
C12H11ClF3NO2
|
1
|
1 |
IC50 = 110 nM
|
|
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CP0408413
|
[7-[(4-chlorophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 2,3-dihydro-1,4-benzoxazine-4-carboxylate
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|
C22H21ClN4O5
|
1
|
1 |
IC50 = 170 nM
|
|
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CP0558348
|
5-(1-methylindolin-5-yl)-1,3,4-oxadiazol-2-ol
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|
C11H11N3O2
|
1
|
1 |
IC50 = 380 nM
|
|
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CP0495592
|
5-(3,4-dichlorophenyl)-1,3,4-oxadiazol-2-ol
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|
C8H4Cl2N2O2
|
1
|
1 |
IC50 = 430 nM
|
|
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CP0560493
|
5-(4-chlorophenyl)-3H-1,3,4-thiadiazol-2-one
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|
C8H5ClN2OS
|
1
|
1 |
IC50 = 940 nM
|
|
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CP0557903
|
5-(4-chlorophenyl)-1,2-oxazol-3-one
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|
C9H6ClNO2
|
1
|
1 |
IC50 = 1600 nM
|
|
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CP0074615
|
5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ol
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|
C8H5ClN2O2
|
1
|
1 |
IC50 = 2100 nM
|
|
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CP0424692
|
1-(4-chlorophenyl)triazole
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|
C8H6ClN3
|
1
|
1 |
IC50 = 2900 nM
|
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CP0560495
|
(5-phenyl-1,2-oxazol-3-yl)methanol
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|
C10H9NO2
|
1
|
1 |
IC50 = 4000 nM
|
|
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CP0152125
|
1,2,3-triazole analogue, 15
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|
C8H6ClN3
|
1
|
1 |
IC50 = 4200 nM
|
|
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CP0546811
|
[1-(4-chlorophenyl)triazol-4-yl]methanol
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|
C9H8ClN3O
|
1
|
1 |
IC50 = 11500 nM
|
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CP0560494
|
(5-phenyl-1,3,4-oxadiazol-2-yl)methanol
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|
C9H8N2O2
|
1
|
1 |
IC50 = 14000 nM
|
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CP0557904
|
(5-phenyl-1,3-oxazol-2-yl)methanol
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|
C10H9NO2
|
1
|
1 |
IC50 = 17000 nM
|
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CP0528366
|
(3-phenyl-1,2-oxazol-5-yl)methanol
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|
C10H9NO2
|
1
|
1 |
IC50 = 19000 nM
|
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CP0574835
|
(5-phenyl-1,2,4-oxadiazol-3-yl)methanol
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|
C9H8N2O2
|
1
|
1 |
IC50 = 36000 nM
|
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CP0560496
|
2-(5-fluoro-1H-indol-3-yl)ethylurea
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|
C11H12FN3O
|
1
|
1 |
IC50 = 37200 nM
|
|
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CP0561951
|
[1-(4-chlorophenyl)-5-methyltriazol-4-yl]methanol
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|
C10H10ClN3O
|
1
|
1 |
IC50 = 42000 nM
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CP0557094
|
(3-phenyl-1,2,4-oxadiazol-5-yl)methanol
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|
C9H8N2O2
|
1
|
1 |
IC50 = 65000 nM
|
|
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CP0572317
|
1-(4-chlorophenyl)pyrazole
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|
C9H7ClN2
|
1
|
1 |
IC50 = 69000 nM
|
|
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CP0114894
|
3-(4-chlorophenyl)-4H-1,2-oxazol-5-one
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|
C9H6ClNO2
|
1
|
1 |
IC50 = 77000 nM
|
|
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CP0088261
|
5-(4-chlorophenyl)-2H-tetrazole
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|
C7H5ClN4
|
1
|
1 |
IC50 > 100000 nM
|
|
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CP0330018
|
3-(4-chlorophenyl)-4H-1,2,4-oxadiazol-5-one
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|
C8H5ClN2O2
|
1
|
1 |
IC50 > 100000 nM
|
|
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CP0507442
|
CHEMBL4743178
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|
C10H9ClN2O
|
1
|
1 |
IC50 > 100000 nM
|
|
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CP0528367
|
(4-methyl-5-phenyl-1,2,4-triazol-3-yl)methanol
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|
C10H11N3O
|
1
|
1 |
IC50 > 100000 nM
|
|
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