| Compound ID |
Compound Name |
Compound Formula |
|
CP0568633
|
1-(2-ethylphenyl)-3,5-dimethyl-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C23H22N4O
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
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CP0546522
|
3,5-dimethyl-1-(2-methylphenyl)-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C22H20N4O
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
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CP0168607
|
1-(2-bromophenyl)-5-methyl-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C20H15BrN4O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0105068
|
N-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide
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|
C27H34N4O5
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
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CP0222485
|
2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(thiophen-2-ylmethyl)acetamide
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|
C27H29FN4O4S
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0153717
|
5-methyl-1-(2-methylphenyl)-N-quinolin-2-yltriazole-4-carboxamide
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|
C20H17N5O
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0133135
|
2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-(2-methylpropyl)-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide
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|
C26H33FN4O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0143651
|
N-(cyclopropylmethyl)-2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide
Show/Hide
|
C26H31FN4O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0551701
|
1-(2-bromophenyl)-3,5-dimethyl-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C21H17BrN4O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0069451
|
2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-propylacetamide
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|
C25H31FN4O4
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0119796
|
2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide
Show/Hide
|
C22H25FN4O4
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0574983
|
3,5-dimethyl-1-(2-propan-2-ylphenyl)-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C24H24N4O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0568634
|
1-(2-bromo-6-fluorophenyl)-3,5-dimethyl-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C21H16BrFN4O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0105072
|
2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(pyridin-2-ylmethyl)acetamide
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|
C28H30FN5O4
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0138202
|
N-benzyl-2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide
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|
C29H31FN4O4
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0351359
|
N-ethyl-2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide
Show/Hide
|
C24H29FN4O4
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0053018
|
2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiopyrano-[4,3-d]pyrimidin-4-ol
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|
C14H11F3N2OS
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0574984
|
1-(2-fluorophenyl)-3,5-dimethyl-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C21H17FN4O
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0567954
|
1-(2,5-dimethylphenyl)-3,5-dimethyl-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C23H22N4O
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0574982
|
3,5-dimethyl-1-phenyl-N-quinolin-2-ylpyrazole-4-carboxamide
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|
C21H18N4O
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0133107
|
2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-methyl-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide
Show/Hide
|
C23H27FN4O4
|
1
|
| 1 |
IC50 = 193 nM
|
|
|
|
CP0222487
|
3-(2-fluorophenyl)-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C22H22FN3O3S
|
1
|
| 1 |
IC50 = 304 nM
|
|
|
|
CP0543093
|
1-(2-chlorophenyl)-3,5-dimethyl-N-quinolin-2-ylpyrazole-4-carboxamide
Show/Hide
|
C21H17ClN4O
|
1
|
| 1 |
IC50 = 305 nM
|
|
|
|
CP0319083
|
3-(4-fluorophenyl)-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C22H22FN3O3S
|
1
|
| 1 |
IC50 = 483 nM
|
|
|
|
CP0118355
|
3-(3-hydroxyphenyl)-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C22H23N3O4S
|
1
|
| 1 |
IC50 = 812 nM
|
|
|
|
CP0222483
|
N-[(4-oxo-3H-quinazolin-2-yl)methyl]-3-phenyl-N-(thiophen-2-ylmethyl)propanamide
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|
C23H21N3O2S
|
1
|
| 1 |
IC50 = 937 nM
|
|
|
|
CP0531564
|
2-[4-(2-hydroxypropan-2-yl)phenyl]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
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|
C16H18N2O3
|
1
|
| 1 |
IC50 = 1030 nM
|
|
|
|
CP0105073
|
4-chloro-5-cyano-N-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methoxybenzamide
Show/Hide
|
C23H23ClFN3O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0467721
|
2-[4-(trifluoromethoxy)phenyl]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
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|
C14H11F3N2O3
|
1
|
| 1 |
IC50 = 1220 nM
|
|
|
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CP0121140
|
3-(4-hydroxyphenyl)-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C22H23N3O4S
|
1
|
| 1 |
IC50 = 1350 nM
|
|
|
|
CP0133133
|
2-[4-(trifluoromethyl)phenyl]-5,6,7,8-tetrahydro-3H-quinazolin-4-one
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|
C15H13F3N2O
|
1
|
| 1 |
IC50 = 1410 nM
|
|
|
|
CP0040805
|
2-[4-(trifluoromethyl)phenyl]-3H-quinazolin-4-one
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|
C15H9F3N2O
|
1
|
| 1 |
IC50 = 1670 nM
|
|
|
|
CP0222484
|
2-[4-(trifluoromethyl)phenyl]-3,6,7,8-tetrahydrothiopyrano[3,2-d]pyrimidin-4-one
Show/Hide
|
C14H11F3N2OS
|
1
|
| 1 |
IC50 = 1720 nM
|
|
|
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CP0118348
|
N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-phenyl-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C22H23N3O3S
|
1
|
| 1 |
IC50 = 1920 nM
|
|
|
|
CP0314006
|
2-[4-(trifluoromethyl)phenyl]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
Show/Hide
|
C14H11F3N2O2
|
1
|
| 1 |
IC50 = 2650 nM
|
|
|
|
CP0133110
|
methyl 4-(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)benzoate
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|
C15H14N2O4
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0222486
|
3-(2-hydroxyphenyl)-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C22H23N3O4S
|
1
|
| 1 |
IC50 = 3770 nM
|
|
|
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CP0075195
|
2-(4-bromophenyl)-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
Show/Hide
|
C13H11BrN2O2
|
1
|
| 1 |
IC50 = 4140 nM
|
|
|
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CP0479862
|
2-[4-(dimethylamino)phenyl]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
Show/Hide
|
C15H17N3O2
|
1
|
| 1 |
IC50 = 4210 nM
|
|
|
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CP0314005
|
2-(4-chlorophenyl)-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
Show/Hide
|
C13H11ClN2O2
|
1
|
| 1 |
IC50 = 4430 nM
|
|
|
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CP0248932
|
2-(4-methylphenyl)-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
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|
C14H14N2O2
|
1
|
| 1 |
IC50 = 4630 nM
|
|
|
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CP0069449
|
2-[4-(trifluoromethyl)phenyl]-4a,5,7,7a-tetrahydro-3H-thieno[3,4-d]pyrimidin-4-one
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|
C13H11F3N2OS
|
1
|
| 1 |
IC50 = 5040 nM
|
|
|
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CP0281602
|
2-(4-methoxyphenyl)-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
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|
C14H14N2O3
|
1
|
| 1 |
IC50 = 5050 nM
|
|
|
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CP0105070
|
2-(4-methylsulfonylphenyl)-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
Show/Hide
|
C14H14N2O4S
|
1
|
| 1 |
IC50 = 6290 nM
|
|
|
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CP0075194
|
3-(3-fluorophenyl)-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C22H22FN3O3S
|
1
|
| 1 |
IC50 = 6610 nM
|
|
|
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CP0105071
|
2-thiophen-3-yl-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
Show/Hide
|
C11H10N2O2S
|
1
|
| 1 |
IC50 = 8090 nM
|
|
|
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CP0118396
|
N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-pyridin-4-yl-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C21H22N4O3S
|
1
|
| 1 |
IC50 = 8250 nM
|
|
|
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CP0069450
|
N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-phenyl-N-(thiophen-3-ylmethyl)propanamide
Show/Hide
|
C22H23N3O3S
|
1
|
| 1 |
IC50 = 8540 nM
|
|
|
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CP0100830
|
2-[4-(trifluoromethyl)phenyl]-3,5,6,8-tetrahydropyrano[3,4-d]pyrimidin-4-one
Show/Hide
|
C14H11F3N2O2
|
1
|
| 1 |
IC50 = 18100 nM
|
|
|
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CP0222488
|
N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-pyridin-3-yl-N-(thiophen-2-ylmethyl)propanamide
Show/Hide
|
C21H22N4O3S
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
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CP0105069
|
N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-phenylpropanamide
Show/Hide
|
C17H19N3O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
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CP0222489
|
N-ethyl-N-[(4-oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-phenylpropanamide
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
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CP0305336
|
2-[(thiophen-2-ylmethylamino)methyl]-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one
Show/Hide
|
C13H15N3O2S
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
