Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04993 , Synaptic vesicular amine transporter
 Protein Info 
Gene Name SLC18A2
Organism Rattus norvegicus, Rat
Protein Classification Transporter
Uniprot ID Q01827
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT04993
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0579591
 Compound Info 
(1R,15R,17S,18S)-3,17-diethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraen-7-ol;hydrochloride
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C21H29ClN2O
  1
1
IC50 = 70 nM
 Bioactivity Info 
   TI
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CP0967180
 Compound Info 
10-Ethoxy-ibogaine
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C21H28N2O
  1
1
IC50 = 80 nM
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CP0567889
 Compound Info 
(1R,15R,17S,18S)-17-ethyl-3-methyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraen-7-ol;hydrochloride
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C20H27ClN2O
  1
1
IC50 = 170 nM
 Bioactivity Info 
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CP0574510
 Compound Info 
(1R,15R,17S,18S)-17-ethyl-3-methyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-7-carbonitrile
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C21H25N3
  1
1
IC50 = 440 nM
 Bioactivity Info 
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CP0969957
 Compound Info 
Noribogaine
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C19H24N2O
  1
1
IC50 = 570 nM
 Bioactivity Info 
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CP0569892
 Compound Info 
(1R,15R,17S,18S)-17-ethyl-7-methoxy-3-methyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene
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C21H28N2O
  1
1
IC50 = 740 nM
 Bioactivity Info 
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CP0546949
 Compound Info 
(1R,15R,17S,18S)-7,17-diethyl-3-methyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene
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C22H30N2
  1
1
IC50 = 750 nM
 Bioactivity Info 
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CP0546948
 Compound Info 
(1R,15R,17S,18S)-17-ethyl-3-methyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene
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C20H26N2
  1
1
IC50 = 1500 nM
 Bioactivity Info 
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CP0970036
 Compound Info 
(1R,15R,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene
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C19H24N2
  1
1
IC50 = 3000 nM
 Bioactivity Info 
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CP0954640
 Compound Info 
(1R,15R,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-7-carbonitrile
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C20H23N3
  1
1
IC50 = 3300 nM
 Bioactivity Info 
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CP0149373
 Compound Info 
(1R,15R,17S,18S)-17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene
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C20H26N2O
  1
1
IC50 = 4000 nM
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CP0954641
 Compound Info 
(1R,15R,17S,18S)-8-bromo-17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene
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C20H25BrN2O
  1
1
IC50 = 4900 nM
 Bioactivity Info 
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