Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04580 , Voltage-dependent L-type calcium channel subunit alpha-1C
Gene Name CACNA1C
Organism Rattus norvegicus, Rat
Protein Classification Ion channel
Uniprot ID P22002
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT04580
 
Compound ID Compound Name Compound Formula
CP0477799
4-[(2R,5R)-1-benzhydryl-5-methylpiperazin-2-yl]butoxy-tert-butyl-dimethylsilane
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C28H44N2OSi
 1
1
IC50 = 1530 nM
   TI
   LI
   LO
   TS
CP0380989
(2R,5R)-1-benzhydryl-2-benzyl-5-methylpiperazine
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C25H28N2
 1
1
IC50 = 1780 nM
   TI
   LI
   LO
   TS
CP0433688
(2R,5R)-1-benzhydryl-5-methyl-2-pentylpiperazine
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C23H32N2
 1
1
IC50 = 1780 nM
   TI
   LI
   LO
   TS
CP0477797
4-[(2R,5R)-1-benzyl-5-methylpiperazin-2-yl]butoxy-tert-butyl-dimethylsilane
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C22H40N2OSi
 1
1
IC50 = 3340 nM
   TI
   LI
   LO
   TS
CP0375435
3-[(2R,5R)-1-benzhydryl-5-methyl-4-(4-methylphenyl)sulfonylpiperazin-2-yl]propoxy-tert-butyl-dimethylsilane
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C34H48N2O3SSi
 1
1
IC50 = 5100 nM
   TI
   LI
   LO
   TS
CP0524037
4-[(2R,5R)-1-benzhydryl-5-methylpiperazin-2-yl]butan-1-ol
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C22H30N2O
 1
1
IC50 = 5400 nM
   TI
   LI
   LO
   TS
CP0537920
(2R,5R)-1-benzyl-5-methyl-2-nonylpiperazine
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C21H36N2
 1
1
IC50 = 5600 nM
   TI
   LI
   LO
   TS
CP0380988
3-[(2R,5R)-1-benzhydryl-5-methylpiperazin-2-yl]propoxy-tert-butyl-dimethylsilane
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C27H42N2OSi
 1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS
CP0477795
4-[(2R,5R)-1-benzhydryl-5-methyl-4-(4-methylphenyl)sulfonylpiperazin-2-yl]butoxy-tert-butyl-dimethylsilane
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C35H50N2O3SSi
 1
1
IC50 = 8200 nM
   TI
   LI
   LO
   TS
CP0536152
(2R,5R)-1-benzyl-5-methyl-2-pentylpiperazine
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C17H28N2
 1
1
IC50 = 9230 nM
   TI
   LI
   LO
   TS
CP0380987
(2R,5R)-1,2-dibenzyl-5-methylpiperazine
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C19H24N2
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0381638
4-[(2R,5R)-1-benzyl-5-methylpiperazin-2-yl]butan-1-ol
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C16H26N2O
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0433690
(2R,5R)-2-benzyl-1-[(4-fluorophenyl)methyl]-5-methyl-4-[4-(trifluoromethyl)phenyl]sulfonylpiperazine
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C26H26F4N2O2S
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0489343
(2R,5R)-2-benzyl-1-[(4-fluorophenyl)methyl]-5-methylpiperazine
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C19H23FN2
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0536151
4-[(2R,5R)-1-benzhydryl-5-methyl-4-[4-(trifluoromethyl)phenyl]sulfonylpiperazin-2-yl]butoxy-tert-butyl-dimethylsilane
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C35H47F3N2O3SSi
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0559125
(2R,5R)-1,2-dibenzyl-5-methyl-4-[4-(trifluoromethyl)phenyl]sulfonylpiperazine
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C26H27F3N2O2S
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS