| Compound ID |
Compound Name |
Compound Formula |
|
CP0178303
|
1-methyl-3-[4-[4-[2-[4-methyl-3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]urea
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|
C25H25N7O3S
|
1
|
| 1 |
IC50 < 0.05 nM
|
|
|
|
CP0178304
|
1-methyl-3-[4-[4-[2-(3-sulfamoylanilino)pyrimidin-4-yl]pyridin-2-yl]phenyl]urea
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|
C23H21N7O3S
|
1
|
| 1 |
IC50 < 0.05 nM
|
|
|
|
CP0186436
|
1-methyl-3-[4-[4-[2-(4-methyl-3-sulfamoylanilino)pyrimidin-4-yl]pyridin-2-yl]phenyl]urea
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|
C24H23N7O3S
|
1
|
| 1 |
IC50 < 0.05 nM
|
|
|
|
CP0200088
|
1-[4-[4-[2-[4-chloro-3-(dimethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
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|
C25H24ClN7O3S
|
1
|
| 1 |
IC50 < 0.05 nM
|
|
|
|
CP0247761
|
1-[4-[4-[2-[4-chloro-3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
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|
C24H22ClN7O3S
|
1
|
| 1 |
IC50 < 0.05 nM
|
|
|
|
CP0253446
|
1-[4-[4-[2-[3-(dimethylsulfamoyl)-4-methylanilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
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|
C26H27N7O3S
|
1
|
| 1 |
IC50 < 0.05 nM
|
|
|
|
CP0178296
|
1-methyl-3-[4-[4-[2-[3-(methylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]urea
Show/Hide
|
C24H23N7O3S
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0120603
|
1-[4-[4-[2-[4-chloro-3-(diethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
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|
C27H28ClN7O3S
|
1
|
| 1 |
IC50 = 0.11 nM
|
|
|
|
CP0178300
|
1-[4-[4-[2-[3-(diethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
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|
C27H29N7O3S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0191346
|
1-[4-[4-[2-[3-(diethylsulfamoyl)-4-methylanilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
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|
C28H31N7O3S
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0197606
|
3-[[4-(2-piperidin-1-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamide
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|
C20H22N6O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0252578
|
3-[[4-[2-(diethylamino)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide
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|
C19H22N6O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0252576
|
3-[[4-[2-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide
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|
C21H22N6O3S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0252577
|
3-[[4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamide
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|
C19H20N6O3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0178274
|
3-[[4-[2-(3-hydroxypropylamino)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide
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|
C18H20N6O3S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0282623
|
3-[[4-[2-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide
Show/Hide
|
C21H22N6O3S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0087616
|
3-[[4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzonitrile
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|
C20H18N6O
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0004084
|
3-[[4-[2-(3-chloroanilino)-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol
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|
C18H18ClN5O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0087619
|
4-(2-morpholin-4-ylpyridin-4-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidin-2-amine
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|
C20H18F3N5O
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0191344
|
N-(3-chlorophenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amine
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|
C19H18ClN5O
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0120601
|
3-[[4-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]pyrimidin-2-yl]amino]benzenesulfonamide
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|
C20H23N7O2S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0178298
|
N-(3-methylphenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amine
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|
C20H21N5O
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0191343
|
4-[[4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-yl]amino]benzenesulfonamide
Show/Hide
|
C19H20N6O3S
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0192166
|
4-[[4-[3-(piperidine-1-carbonyl)phenyl]pyrimidin-2-yl]amino]benzenesulfonamide
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|
C22H23N5O3S
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0087618
|
N-(4-chlorophenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amine
Show/Hide
|
C19H18ClN5O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0247762
|
N-(3-methoxyphenyl)-4-(2-morpholin-4-ylpyridin-4-yl)pyrimidin-2-amine
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0247763
|
4-(2-morpholin-4-ylpyridin-4-yl)-N-phenylpyrimidin-2-amine
Show/Hide
|
C19H19N5O
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
