Brief Information of the Compound and Protein
Compound Name
1-[4-[4-[2-[4-chloro-3-(dimethylsulfamoyl)anilino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methylurea
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PubChem ID
CID: 71460422
Canonical SMILES
CNC(=O)Nc1ccc(cc1)-c1cc(ccn1)-c1ccnc(Nc2ccc(Cl)c(c2)S(=O)(=O)N(C)C)n1
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Compound Formula C25H24ClN7O3S
Compound Structure
Protein Name
Serine/threonine-protein kinase SMG1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
Uniprot ID
Q96Q15
Gene Name
SMG1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 < 0.05 nM
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