Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04413 , Vitamin K epoxide reductase complex subunit 1
Gene Name VKORC1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9BQB6
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT04413
 
Compound ID Compound Name Compound Formula
CP0944442
rac-4-(cycloocta-1,3,5,7-tetraenyl)-2-hydroxy-2-methyl-3,4-dihydropyrano[3,2-c]chromen-5(2H)-one
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C21H18O4
 1
1
IC50 = 4.5 nM
   TI
   LI
   LO
   TS
CP0062501
2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one
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C19H16O4
 1
1
IC50 = 8.8 nM
   TI
   LI
   LO
   TS
CP0956189
(3'R,6R,8S)-6-(cycloocta-1,3,5,7-tetraenyl)-8-hydroxy-8-methyl-2-phenyl-7,8-dihydrospiro[[1,2,4]triazolo[1,2-a]pyridazine-5,3'-chroman]-1,3,4'(2H,6H)-trione
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C29H25N3O5
 1
1
IC50 = 58.2 nM
   TI
   LI
   LO
   TS
CP0468886
3-(1-cyclooctyl-3-oxobutyl)-4-hydroxychromen-2-one
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C21H26O4
 1
1
IC50 = 59 nM
   TI
   LI
   LO
   TS
CP0468887
3-(1-cyclohexyl-3-oxobutyl)-4-hydroxychromen-2-one
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C19H22O4
 1
1
IC50 = 90.2 nM
   TI
   LI
   LO
   TS
CP0954385
rac-4-(1-(4-hydroxy-2-oxo-2H-chromen-3-yl)-3-oxobutyl)cycloocta-1,3,5,7-tetraenecarboxylic acid
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C22H18O6
 1
1
IC50 = 1929 nM
   TI
   LI
   LO
   TS