Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04404 , Sodium channel protein type 9 subunit alpha
 Protein Info 
Gene Name SCN9A
Organism Rattus norvegicus, Rat
Protein Classification Ion channel
Uniprot ID O08562
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT04404
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0027141
 Compound Info 
3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
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C24H20F3N3O3
  1
1
IC50 = 74 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0405006
 Compound Info 
2-(4,4-difluorocyclohexyl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
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C23H21F5N2O3
  1
1
IC50 = 74 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0017968
 Compound Info 
3-cyano-4-[2-[2-[(2-piperidin-4-ylethylamino)methyl]pyridin-4-yl]-4-[3-(trifluoromethyl)phenyl]phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C35H32F3N7O3S2
  1
1
IC50 = 75 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0319111
 Compound Info 
4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-3-fluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C18H13ClFN5O3S2
  1
1
IC50 = 124 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0010999
 Compound Info 
4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
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C18H12Cl2FN5O3S2
  1
1
IC50 = 153 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0168191
 Compound Info 
4-[4-chloro-2-(2-methylpyrazol-3-yl)phenoxy]-3-cyano-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide
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C19H13ClN6O3S2
  1
1
IC50 = 813 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0032962
 Compound Info 
2-(oxan-4-yl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
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C22H21F3N2O4
  1
1
IC50 = 1600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0247315
 Compound Info 
4-[4-chloro-2-[2-(1-ethylazetidin-3-yl)pyrazol-3-yl]phenoxy]-3-cyano-N-(1,3-thiazol-4-yl)benzenesulfonamide
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C24H21ClN6O3S2
  1
1
IC50 = 3140 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0254953
 Compound Info 
5-chloro-2-fluoro-4-[2-pyridazin-4-yl-4-(trifluoromethyl)phenoxy]-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
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C19H10ClF4N5O3S2
  1
1
IC50 = 5450 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS