Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT04106 , DNA dC->dU-editing enzyme APOBEC-3G
Gene Name APOBEC3G
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9HC16
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT04106
 
Compound ID Compound Name Compound Formula
CP0948402
6-nitro-2-oxo-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)-1,2-dihydroquinoline-4-carboxamide
   Show/Hide
C17H10N6O4S
 2
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
2
IC50 = 23000 nM
   TI
   LI
   LO
   TS
CP0849650
1-(2-oxo-1,2-dihydroquinoline-4-carbonyl)-1H-1,2,4-triazole-5-carbonitrile
   Show/Hide
C13H7N5O2
 2
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
2
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0849649
6-methoxy-2-oxo-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)-1,2-dihydroquinoline-4-carboxamide
   Show/Hide
C18H13N5O3S
 2
1
IC50 = 17000 nM
   TI
   LI
   LO
   TS
2
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0903156
6-amino-2-oxo-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)-1,2-dihydroquinoline-4-carboxamide
   Show/Hide
C17H12N6O2S
 2
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
2
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0903157
6-hydroxy-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)nicotinamide
   Show/Hide
C13H9N5O2S
 2
1
IC50 = 21000 nM
   TI
   LI
   LO
   TS
2
IC50 = 31000 nM
   TI
   LI
   LO
   TS
CP0871767
2-chloro-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)quinoline-4-carboxamide
   Show/Hide
C17H10ClN5OS
 2
1
IC50 = 22000 nM
   TI
   LI
   LO
   TS
2
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0903162
2-bromo-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)quinoline-4-carboxamide
   Show/Hide
C17H10BrN5OS
 2
1
IC50 = 32000 nM
   TI
   LI
   LO
   TS
2
IC50 = 52000 nM
   TI
   LI
   LO
   TS
CP0871768
2-hydroxy-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)isonicotinamide
   Show/Hide
C13H9N5O2S
 1
1
IC50 = 60000 nM
   TI
   LI
   LO
   TS
CP0674352
2-Oxo-N-(5-pyridin-4-yl)-1,3,4-thiadiazol-2-yl)-1,2-dihydroquinoline-4-carboxamide
   Show/Hide
C17H11N5O2S
 2
1
IC50 = 90000 nM
   TI
   LI
   LO
   TS
2
IC50 > 100000 nM
   TI
   LI
   LO
   TS