General Information of the Compound
| Compound ID |
CP0849649
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| Compound Name |
6-methoxy-2-oxo-N-(5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl)-1,2-dihydroquinoline-4-carboxamide
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| Structure |
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| Formula |
C18H13N5O3S
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| Molecular Weight |
379.401
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| Canonical SMILES |
COc1ccc2[nH]c(=O)cc(C(=O)Nc3nnc(-c4ccncc4)s3)c2c1
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| InChI |
InChI=1S/C18H13N5O3S/c1-26-11-2-3-14-12(8-11)13(9-15(24)20-14)16(25)21-18-23-22-17(27-18)10-4-6-19-7-5-10/h2-9H,1H3,(H,20,24)(H,21,23,25)
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| InChIKey |
ONJKXZHDPBIRRB-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04119, DNA dC->dU-editing enzyme APOBEC-3A
Protein ID: PT07131, DNA dC->dU-editing enzyme APOBEC-3B
Protein ID: PT04106, DNA dC->dU-editing enzyme APOBEC-3G