| Compound ID |
Compound Name |
Compound Formula |
|
CP0488487
|
N-(3-chloro-4-fluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H15ClFN5
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0390687
|
(1H-Benzoimidazol-2-yl)-(R)-1,2,3,4-tetrahydronaphthalen-1-ylamine
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|
C17H17N3
|
3
|
| 1 |
EC50 = 400 nM
|
|
|
| 2 |
EC50 = 2200 nM
|
|
|
| 3 |
Kd = 100 nM
|
|
|
|
CP0495333
|
N-(5-chloro-2-fluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H15ClFN5
|
1
|
| 1 |
EC50 = 600 nM
|
|
|
|
CP0519185
|
(1H-Benzoimidazol-2-yl)-(6,7-dichloro-1,2,3,4-tetrahydronaphthalen-1-yl)amine
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|
C17H15Cl2N3
|
2
|
| 1 |
EC50 = 1810 nM
|
|
|
| 2 |
Kd = 7.8 nM
|
|
|
|
CP0211850
|
Apamin
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|
C79H131N31O24S4
|
2
|
| 1 |
IC50 = 0.064 nM
|
|
|
| 2 |
IC50 = 0.168 nM
|
|
|
|
CP0375052
|
N-(4-methylpyridin-2-yl)-4-pyridin-2-yl-1,3-thiazol-2-amine
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|
C14H12N4S
|
3
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 56 nM
|
|
|
| 3 |
IC50 = 59 nM
|
|
|
|
CP0383396
|
N,4-dipyridin-2-yl-1,3-thiazol-2-amine
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|
C13H10N4S
|
3
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
IC50 = 290 nM
|
|
|
| 3 |
IC50 = 543 nM
|
|
|
|
CP0401123
|
5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
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|
C11H9ClN4S
|
2
|
| 1 |
IC50 = 350 nM
|
|
|
| 2 |
IC50 = 580 nM
|
|
|
|
CP0401122
|
(R)-5-chloro-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
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|
C14H13ClN4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0388337
|
N-benzyl-5-chloropyrazolo[1,5-a]pyrimidin-7-amine
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|
C13H11ClN4
|
2
|
| 1 |
IC50 = 1100 nM
|
|
|
| 2 |
IC50 = 1600 nM
|
|
|
|
CP0683533
|
SID50106101
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|
C30H40Cl2N4
|
2
|
| 1 |
IC50 = 1300 nM
|
|
|
| 2 |
IC50 = 2000 nM
|
|
|
|
CP0867692
|
1,1'-(1,3-phenylenebis(methylene))bis(8-isopropyl-2-methylisoquinolinium)iodide
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|
C34H38I2N2
|
2
|
| 1 |
IC50 = 2970 nM
|
|
|
| 2 |
Ki = 46 nM
|
|
|
|
CP0383141
|
5-chloro-N-(3-chlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
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|
C13H10Cl2N4
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0519732
|
5-chloro-N-(1,2-diphenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
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|
C20H17ClN4
|
1
|
| 1 |
IC50 = 7500 nM
|
|
|
|
CP0460362
|
5-chloro-N-(3-nitrobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
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|
C13H10ClN5O2
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
|
CP0383142
|
5-chloro-N-(2-(trifluoromethoxy)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine
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|
C14H10ClF3N4O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0460361
|
5-chloro-N-(3-methylbenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C14H13ClN4
|
1
|
| 1 |
IC50 = 10700 nM
|
|
|
|
CP0519731
|
5-chloro-N-(3-(trifluoromethoxy)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine
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|
C14H10ClF3N4O
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0422721
|
5-chloro-N-(3-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C14H10ClF3N4
|
1
|
| 1 |
IC50 = 14600 nM
|
|
|
|
CP0460360
|
5-chloro-N-(2-methylbenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C14H13ClN4
|
1
|
| 1 |
IC50 = 14600 nM
|
|
|
|
CP0522893
|
5-chloro-N-(4-(trifluoromethoxy)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C14H10ClF3N4O
|
1
|
| 1 |
IC50 = 15400 nM
|
|
|
|
CP0473899
|
5-chloro-N-(2-methoxybenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
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|
C14H13ClN4O
|
1
|
| 1 |
IC50 = 15900 nM
|
|
|
|
CP0397147
|
5-chloro-N-(2-chlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C13H10Cl2N4
|
1
|
| 1 |
IC50 = 19100 nM
|
|
|
|
CP0042911
|
N-phenyl-4-pyridin-2-yl-1,3-thiazol-2-amine
Show/Hide
|
C14H11N3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0128555
|
N-pyridin-2-yl-4-pyridin-3-yl-1,3-thiazol-2-amine
Show/Hide
|
C13H10N4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0417754
|
N,4-diphenyl-1,3-thiazol-2-amine
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|
C15H12N2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0428143
|
4-pyridin-2-yl-N-pyridin-4-yl-1,3-thiazol-2-amine
Show/Hide
|
C13H10N4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0474541
|
2-(4-(pyridin-2-yl)thiazol-2-yl)pyridine
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|
C13H9N3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0480506
|
2-(2-(pyridin-2-ylmethyl)thiazol-4-yl)pyridine
Show/Hide
|
C14H11N3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0486792
|
5-iodo-N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-2-amine
Show/Hide
|
C13H9IN4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0494652
|
4-pyridin-2-yl-N-pyrimidin-2-yl-1,3-thiazol-2-amine
Show/Hide
|
C12H9N5S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0495902
|
3-chloro-N-(4-(pyridin-2-yl)thiazol-2-yl)-5-(trifluoromethyl)pyridin-2-amine
Show/Hide
|
C14H8ClF3N4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0498523
|
N-pyridin-2-yl-4-pyridin-4-yl-1,3-thiazol-2-amine
Show/Hide
|
C13H10N4S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0383143
|
5-chloro-N-(4-phenoxybenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C19H15ClN4O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0397148
|
5-chloro-N-(3,4-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C13H9Cl3N4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0401121
|
5-chloro-N-(4-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C14H10ClF3N4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0422720
|
5-chloro-N-(2-(trifluoromethyl)benzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C14H10ClF3N4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0422854
|
5-chloro-N-(4-chlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C13H10Cl2N4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0422855
|
5-chloro-N-(4-methylbenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C14H13ClN4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0422857
|
5-chloro-N-(4-nitrobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C13H10ClN5O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0519730
|
5-chloro-N-(3,5-dichlorobenzyl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
|
C13H9Cl3N4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0858748
|
1,1'-(butane-1,4-diyl)bis(8-isopropyl-2-methylisoquinolinium)iodide
Show/Hide
|
C30H38I2N2
|
1
|
| 1 |
Ki = 214 nM
|
|
|
|
CP0894247
|
1,1'-(pentane-1,5-diyl)bis(8-isopropyl-2-methylisoquinolinium)iodide
Show/Hide
|
C31H40I2N2
|
1
|
| 1 |
Ki = 575 nM
|
|
|
|
CP0916019
|
1,1'-(propane-1,3-diyl)bis(8-isopropyl-2-methylisoquinolinium)iodide
Show/Hide
|
C29H36I2N2
|
1
|
| 1 |
Ki = 837 nM
|
|
|
|
CP0851749
|
1,1'-(1,4-phenylenebis(methylene))bis(8-isopropyl-2-methylisoquinolinium)iodide
Show/Hide
|
C34H38I2N2
|
1
|
| 1 |
Ki = 1268 nM
|
|
|
