Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT03401 , Sodium-dependent dopamine transporter
 Protein Info 
Gene Name SLC6A3
Organism Mus musculus, Mouse
Protein Classification Transporter
Uniprot ID Q61327
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT03401
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0393494
 Compound Info 
methyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate
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C20H18ClN5O4S
  2
1
EC50 = 810 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 940 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0405283
 Compound Info 
ethyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate
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C21H20ClN5O4S
  2
1
EC50 = 1070 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1170 nM
 Bioactivity Info 
   TI
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   LO
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CP0393811
 Compound Info 
(1S,2R,3S,4R,5S)-4-[2-[2-(5-bromothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C20H19BrN6O3S
  2
1
EC50 = 1100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 3260 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0089367
 Compound Info 
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C20H19ClN6O3S
  2
1
EC50 = 2230 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 2290 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393806
 Compound Info 
(1S,2R,3S,4R,5S)-4-[6-[2-(5-chlorothiophen-2-yl)ethynyl]-4-(methylamino)imidazo[4,5-c]pyridin-1-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C21H20ClN5O3S
  2
1
EC50 = 2760 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 4300 nM
 Bioactivity Info 
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   LI
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CP0062351
 Compound Info 
42-548
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C16H13ClN2O
  2
1
IC50 = 13 nM
 Bioactivity Info 
   TI
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2
Ki = 404 nM
 Bioactivity Info 
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CP0035807
 Compound Info 
Cocaine
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C17H21NO4
  2
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 850 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS