| Compound ID |
Compound Name |
Compound Formula |
|
CP0239872
|
(+)-(S)-amphetamine
Show/Hide
|
C9H13N
|
5
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
EC50 = 3.98 nM
|
|
|
| 3 |
EC50 = 84.6 nM
|
|
|
| 4 |
EC50 = 210 nM
|
|
|
| 5 |
EC50 = 218.8 nM
|
|
|
|
CP0403658
|
(4S)-4-[(N-ethylanilino)methyl]-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
|
C12H17N3O
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0428087
|
3-chloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16ClN3
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0453149
|
N-methyl-2-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]ethanamine
Show/Hide
|
C17H18F3NO
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0125122
|
(S)Methamphetamine
Show/Hide
|
C10H15N
|
5
|
| 1 |
EC50 = 17.81 nM
|
|
|
| 2 |
EC50 = 70 nM
|
|
|
| 3 |
EC50 = 278.9 nM
|
|
|
| 4 |
EC50 = 920 nM
|
|
|
| 5 |
EC50 = 1822 nM
|
|
|
|
CP0422195
|
2-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]ethanamine
Show/Hide
|
C16H16F3NO
|
1
|
| 1 |
EC50 = 20.2 nM
|
|
|
|
CP0462482
|
2-[4-[(4-nitrophenyl)methoxy]phenyl]ethanamine
Show/Hide
|
C15H16N2O3
|
1
|
| 1 |
EC50 = 21.5 nM
|
|
|
|
CP0328861
|
4-chloro-N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16ClN3
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0399251
|
N-(1H-imidazol-5-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H17N3
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0491924
|
2-[4-(4-fluorophenoxy)-3-iodophenyl]-N-methylethanamine
Show/Hide
|
C15H15FINO
|
1
|
| 1 |
EC50 = 32.5 nM
|
|
|
|
CP0442393
|
2-(3-iodo-4-phenoxyphenyl)ethanamine
Show/Hide
|
C14H14INO
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0517844
|
1-(diaminomethylidene)-2-[(3,4-dichlorophenyl)methyl]guanidine
Show/Hide
|
C9H11Cl2N5
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0419527
|
2-[4-[(4-fluorophenyl)methoxy]phenyl]ethanamine
Show/Hide
|
C15H16FNO
|
1
|
| 1 |
EC50 = 38.5 nM
|
|
|
|
CP0061725
|
14C-phenylethylamine
Show/Hide
|
C8H11N
|
5
|
| 1 |
EC50 = 47.3 nM
|
|
|
| 2 |
EC50 = 58.6 nM
|
|
|
| 3 |
EC50 = 120 nM
|
|
|
| 4 |
EC50 = 138 nM
|
|
|
| 5 |
EC50 = 189 nM
|
|
|
|
CP0464706
|
N-methyl-2-(4-phenylmethoxyphenyl)ethanamine
Show/Hide
|
C16H19NO
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0110511
|
(R)-amphetamine
Show/Hide
|
C9H13N
|
5
|
| 1 |
EC50 = 65 nM
|
|
|
| 2 |
EC50 = 104.5 nM
|
|
|
| 3 |
EC50 = 121 nM
|
|
|
| 4 |
EC50 = 785.5 nM
|
|
|
| 5 |
EC50 = 4960 nM
|
|
|
|
CP0898501
|
N-methyl-3-[(4-phenoxyphenyl)oxy]propylamine hydrochloride
Show/Hide
|
C16H20ClNO2
|
1
|
| 1 |
EC50 = 66 nM
|
|
|
|
CP0442208
|
N-ethyl-2-(4-phenylmethoxyphenyl)ethanamine
Show/Hide
|
C17H21NO
|
1
|
| 1 |
EC50 = 71 nM
|
|
|
|
CP0366108
|
N-(1H-imidazol-5-ylmethyl)-3-methoxy-N-propan-2-ylaniline
Show/Hide
|
C14H19N3O
|
1
|
| 1 |
EC50 = 72 nM
|
|
|
|
CP0436685
|
2-[4-(4-phenylbutoxy)phenyl]ethanamine
Show/Hide
|
C18H23NO
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0462483
|
2-[4-(2-aminoethyl)phenoxy]-1-phenylethanone
Show/Hide
|
C16H17NO2
|
1
|
| 1 |
EC50 = 83 nM
|
|
|
|
CP0394015
|
2-[(3-chlorophenyl)methyl]-1-(diaminomethylidene)guanidine
Show/Hide
|
C9H12ClN5
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0442211
|
2-[4-[(3,5-dimethylphenyl)methoxy]phenyl]ethanamine
Show/Hide
|
C17H21NO
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0351659
|
N-(1H-imidazol-5-ylmethyl)-6-methoxy-N-propan-2-ylpyridin-2-amine
Show/Hide
|
C13H18N4O
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0877959
|
2-(1-phenoxynaphthalen-4-yl)ethylamine
Show/Hide
|
C18H18ClNO
|
1
|
| 1 |
EC50 = 101 nM
|
|
|
|
CP0432595
|
2-[4-(3-phenylpropoxy)phenyl]ethanamine
Show/Hide
|
C17H21NO
|
1
|
| 1 |
EC50 = 102 nM
|
|
|
|
CP0432593
|
2-(3-iodo-4-phenylmethoxyphenyl)-N-methylethanamine
Show/Hide
|
C16H18INO
|
1
|
| 1 |
EC50 = 106 nM
|
|
|
|
CP0847713
|
N,N-dimethyl-5-(4-phenoxybenzamido)pentylamine hydrochloride
Show/Hide
|
C20H27ClN2O2
|
1
|
| 1 |
EC50 = 109 nM
|
|
|
|
CP0391084
|
3-methyl-thyronamine
Show/Hide
|
C15H17NO2
|
1
|
| 1 |
EC50 = 116 nM
|
|
|
|
CP0442394
|
2-[4-[(3,5-dimethoxyphenyl)methoxy]phenyl]ethanamine
Show/Hide
|
C17H21NO3
|
1
|
| 1 |
EC50 = 123 nM
|
|
|
|
CP0379778
|
(R)Methamphetamine
Show/Hide
|
C10H15N
|
4
|
| 1 |
EC50 = 125.5 nM
|
|
|
| 2 |
EC50 = 843.3 nM
|
|
|
| 3 |
EC50 = 1596 nM
|
|
|
| 4 |
EC50 = 2440 nM
|
|
|
|
CP0419530
|
2-(4-phenylmethoxyphenyl)ethanamine
Show/Hide
|
C15H17NO
|
1
|
| 1 |
EC50 = 168 nM
|
|
|
|
CP0385944
|
4-[4-(2-aminoethyl)-2-iodophenoxy]phenol
Show/Hide
|
C14H14INO2
|
1
|
| 1 |
EC50 = 189 nM
|
|
|
|
CP0485667
|
N,N-dimethyl-2-(4-phenylmethoxyphenyl)ethanamine
Show/Hide
|
C17H21NO
|
1
|
| 1 |
EC50 = 192 nM
|
|
|
|
CP0419528
|
2-[4-[(3-methoxyphenyl)methoxy]phenyl]ethanamine
Show/Hide
|
C16H19NO2
|
1
|
| 1 |
EC50 = 194 nM
|
|
|
|
CP0553804
|
2-[4-(2-phenylethoxy)phenyl]ethanamine
Show/Hide
|
C16H19NO
|
1
|
| 1 |
EC50 = 207 nM
|
|
|
|
CP0453146
|
4-[2-iodo-4-[2-(methylamino)ethyl]phenoxy]phenol
Show/Hide
|
C15H16INO2
|
1
|
| 1 |
EC50 = 221 nM
|
|
|
|
CP0459809
|
2-(3-iodo-4-phenylmethoxyphenyl)ethanamine
Show/Hide
|
C15H16INO
|
1
|
| 1 |
EC50 = 221 nM
|
|
|
|
CP0456266
|
4-[[4-(2-aminoethoxy)-2-methylphenyl]methyl]aniline
Show/Hide
|
C16H20N2O
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0392573
|
4-[(2S)-2-aminopropyl]phenol
Show/Hide
|
C9H13NO
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0441793
|
2-[3-iodo-4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]ethanamine
Show/Hide
|
C16H15F3INO
|
1
|
| 1 |
EC50 = 284 nM
|
|
|
|
CP0284355
|
2-(4-Phenoxy-phenyl)-ethylamine
Show/Hide
|
C14H15NO
|
1
|
| 1 |
EC50 = 296 nM
|
|
|
|
CP0882579
|
2-(4-(4-hydroxyphenoxy)-3-iodophenyl)ethanaminium chloride
Show/Hide
|
C14H15ClINO2
|
1
|
| 1 |
EC50 = 314 nM
|
|
|
|
CP0483553
|
3,5-Diiodothyronamine
Show/Hide
|
C14H13I2NO2
|
1
|
| 1 |
EC50 = 371 nM
|
|
|
|
CP0011288
|
2-Chloro-Phenyl biguanide
Show/Hide
|
C8H10ClN5
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0410151
|
2-[(2-chlorophenyl)methyl]-1-(diaminomethylidene)guanidine
Show/Hide
|
C9H12ClN5
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
|
CP0847935
|
2-(4-phenoxyphenyl)ethanaminium chloride
Show/Hide
|
C14H16ClNO
|
1
|
| 1 |
EC50 = 420 nM
|
|
|
|
CP0880571
|
3-[(4-phenoxyphenyl)oxy]propylamine hydrochloride
Show/Hide
|
C15H18ClNO2
|
1
|
| 1 |
EC50 = 433 nM
|
|
|
|
CP0844897
|
N,N-dimethyl-3-[(4-phenoxyphenyl)oxy]propylamine hydrochloride
Show/Hide
|
C17H22ClNO2
|
1
|
| 1 |
EC50 = 464 nM
|
|
|
|
CP0462140
|
3-chloro-N-(1H-imidazol-2-ylmethyl)-N-propan-2-ylaniline
Show/Hide
|
C13H16ClN3
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0519601
|
1-(diaminomethylidene)-2-[(3-fluorophenyl)methyl]guanidine
Show/Hide
|
C9H12FN5
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0481310
|
2-benzyl-1-(diaminomethylidene)guanidine
Show/Hide
|
C9H13N5
|
1
|
| 1 |
EC50 = 780 nM
|
|
|
|
CP0863688
|
1-(4'-Chlorobenzyl)biguanide dihydrochloride
Show/Hide
|
C9H14Cl3N5
|
1
|
| 1 |
EC50 = 780 nM
|
|
|
|
CP0504826
|
4-[[4-(2-aminoethyl)phenyl]methyl]aniline
Show/Hide
|
C15H18N2
|
1
|
| 1 |
EC50 = 800 nM
|
|
|
|
CP0844896
|
3-[(3-phenoxyphenyl)oxy]propylamine hydrochloride
Show/Hide
|
C15H18ClNO2
|
1
|
| 1 |
EC50 = 885 nM
|
|
|
|
CP0847934
|
5-(4-phenoxybenzamido)pentylamine hydrochloride
Show/Hide
|
C18H23ClN2O2
|
1
|
| 1 |
EC50 = 905 nM
|
|
|
|
CP0877538
|
2-(4-phenoxyphenyl)but-3-yn-1-amine hydrochloride
Show/Hide
|
C16H16ClNO
|
1
|
| 1 |
EC50 = 929 nM
|
|
|
|
CP0436590
|
3,3'-Diiodothyronamine
Show/Hide
|
C14H13I2NO2
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0442569
|
4-[4-(2-aminoethyl)phenoxy]phenol
Show/Hide
|
C14H15NO2
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0176258
|
4-[[4-(2-aminoethoxy)phenyl]methyl]aniline
Show/Hide
|
C15H18N2O
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0410150
|
4-Methyl-Phenyl biguanide
Show/Hide
|
C9H13N5
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0930379
|
1-(3'-Bromobenzyl)biguanide dihydrochloride
Show/Hide
|
C9H14BrCl2N5
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0005986
|
4-Chloro-Phenyl biguanide
Show/Hide
|
C8H10ClN5
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0381568
|
4-[[4-(2-aminoethoxy)phenyl]methyl]phenol
Show/Hide
|
C15H17NO2
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0393245
|
N-(diaminomethylidene)-4-phenylpiperazine-1-carboximidamide
Show/Hide
|
C12H18N6
|
1
|
| 1 |
EC50 = 2380 nM
|
|
|
|
CP0852853
|
N-{[4-(2-Chlorophenyl)piperazin-1-yl]-(imino)methyl}guanidine dihydrochloride
Show/Hide
|
C12H19Cl3N6
|
1
|
| 1 |
EC50 = 2660 nM
|
|
|
|
CP0339207
|
CHEBI:8455
Show/Hide
|
C11H16ClN5
|
1
|
| 1 |
EC50 = 5400 nM
|
|
|
|
CP0441305
|
4-[(2R)-2-aminopropyl]phenol
Show/Hide
|
C9H13NO
|
1
|
| 1 |
EC50 = 5650 nM
|
|
|
|
CP0852852
|
N-{Imino-[4-(pyrimidin-2-yl)piperazin-1-yl]methyl}guanidine dihydrochloride
Show/Hide
|
C10H18Cl2N8
|
1
|
| 1 |
EC50 = 9000 nM
|
|
|
|
CP0844891
|
2-(4-phenoxyphenyl)-3-phenylpropan-1-amine hydrochloride
Show/Hide
|
C21H22ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0844892
|
2-methyl-2-(4-phenoxyphenyl)propan-1-amine hydrochloride
Show/Hide
|
C16H20ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0844895
|
3-(4-phenoxybenzamido)propylamine hydrochloride
Show/Hide
|
C16H19ClN2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0847711
|
2-(4-phenoxyphenyl)-2-phenylethylamine hydrochloride
Show/Hide
|
C20H20ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0847714
|
2-(1-phenoxynaphthalen-4-yl)-2-phenylethylamine hydrochloride
Show/Hide
|
C24H22ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0847715
|
2-(4-phenoxyphenyl)-4-phenylbut-3-yn-1-amine hydrochloride
Show/Hide
|
C22H20ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0847839
|
2-(1-methoxynaphthalen-4-yl)-2-phenylethylamine hydrochloride
Show/Hide
|
C19H20ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0847840
|
2-(4-phenoxybenzamido)ethylamine hydrochloride
Show/Hide
|
C15H17ClN2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0868921
|
N,N-dimethyl-3-(4-phenoxybenzamido)propylamine hydrochloride
Show/Hide
|
C18H23ClN2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0877539
|
2-(4-phenoxyphenyl)propan-1-amine hydrochloride
Show/Hide
|
C15H18ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0877540
|
N,N-dimethyl-4-(4-phenoxybenzamido)butylamine hydrochloride
Show/Hide
|
C19H25ClN2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0877741
|
N,N-dimethyl-2-(4-phenoxybenzamido)ethylamine hydrochloride
Show/Hide
|
C17H21ClN2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0898502
|
2-(3-phenoxyphenyl)-2-phenylethylamine hydrochloride
Show/Hide
|
C20H20ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0898503
|
2-(1-hydroxynaphthalen-4-yl)-2-phenylethylamine hydrochloride
Show/Hide
|
C18H18ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0918263
|
4-(4-phenoxybenzamido)butylamine hydrochloride
Show/Hide
|
C17H21ClN2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0919876
|
7-phenoxy-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine hydrochloride
Show/Hide
|
C22H22ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0921536
|
8-phenoxy-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine hydrochloride
Show/Hide
|
C22H22ClNO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0419533
|
2-[4-[(2,3,4,5,6-pentafluorophenyl)methoxy]phenyl]ethanamine
Show/Hide
|
C15H12F5NO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0432594
|
2-[3-iodo-4-(p-hydroxy)phenoxyphenyl]ethanol
Show/Hide
|
C14H13IO3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0436589
|
N-[2-(4-phenylmethoxyphenyl)ethyl]butan-1-amine
Show/Hide
|
C19H25NO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0436591
|
3,3',5,5'-tetraiodothyronamine
Show/Hide
|
C14H11I4NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0439414
|
3,3',5'-triiodothyronamine
Show/Hide
|
C14H12I3NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0442395
|
N-benzyl-2-(4-phenylmethoxyphenyl)ethanamine
Show/Hide
|
C22H23NO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0449800
|
3'-iodothyronamine
Show/Hide
|
C14H14INO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0459808
|
2-[3-iodo-4-(4-methoxyphenoxy)phenyl]-N-methylethanamine
Show/Hide
|
C16H18INO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0462481
|
N-[2-(4-phenylmethoxyphenyl)ethyl]propan-1-amine
Show/Hide
|
C18H23NO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0464718
|
3,3',5-triiodothyronamine
Show/Hide
|
C14H12I3NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0491925
|
3',5'-diiodothyronamine
Show/Hide
|
C14H13I2NO2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0515820
|
2-[3-iodo-4-[4-(trifluoromethyl)phenoxy]phenyl]-N-methylethanamine
Show/Hide
|
C16H15F3INO
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0476857
|
US9416127, 12
Show/Hide
|
C19H18ClN5O2
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0928985
|
US9181230, 13
Show/Hide
|
C19H17F2N3O
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0561195
|
US9416127, 13
Show/Hide
|
C20H18F3N5O2
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0484426
|
US10501411, Example 128
Show/Hide
|
C20H23ClN2O2
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0491876
|
US10501411, Example 122
Show/Hide
|
C20H21F3N2O2
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0539902
|
US10501411, Example 125
Show/Hide
|
C20H21F3N2O3
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0531619
|
US9181230, 27
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0919389
|
US9181230, 8
Show/Hide
|
C19H18ClN3O
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0922778
|
US9181230, 9
Show/Hide
|
C19H18ClN3O
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0406846
|
US9416127, 10
Show/Hide
|
C20H18F3N5O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0537360
|
US9416127, 6
Show/Hide
|
C19H18ClN5O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0393352
|
US10501411, Example 120
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0542953
|
US9029370, 93
Show/Hide
|
C21H19ClF2N4O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0491094
|
US8802673, 62
Show/Hide
|
C16H18BrN3O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0519044
|
US8802673, 8
Show/Hide
|
C16H17ClN2O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0555392
|
US8802673, 52
Show/Hide
|
C19H18ClN3O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0512214
|
US9181230, 12
Show/Hide
|
C20H18N4O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0386662
|
US10501411, Example 121
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0478803
|
US10501411, Example 20
Show/Hide
|
C17H17ClN2O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0493428
|
US10501411, Example 311
Show/Hide
|
C18H18F3N3O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0555958
|
US10501411, Example 32
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0541862
|
US9029370, 90
Show/Hide
|
C21H19F3N4O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0491088
|
US8802673, 164
Show/Hide
|
C19H20N4O
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0520281
|
US8802673, 83
Show/Hide
|
C16H18ClN3O
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0512216
|
US9181230, 26
Show/Hide
|
C19H18FN3O
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0404996
|
US10501411, Example 33
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0429136
|
US10501411, Example 2
Show/Hide
|
C18H20Cl2N4O
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0469621
|
US10501411, Example 127
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0500335
|
US8802673, 44
Show/Hide
|
C20H20N2O
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0939771
|
US9181230, 29
Show/Hide
|
C19H18FN3O
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0553586
|
US9416127, 18
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0393340
|
US10501411, Example 58
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0413466
|
US10501411, Example 312
Show/Hide
|
C18H18F3N3O2
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0553955
|
US10501411, Example 16
Show/Hide
|
C17H17ClN2O
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0474479
|
US9029370, 60
Show/Hide
|
C19H17BrF2N4O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0490531
|
US8802673, 99
Show/Hide
|
C15H15ClFN3O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0491096
|
US8802673, 82
Show/Hide
|
C16H15ClF3N3O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0519048
|
US8802673, 54
Show/Hide
|
C19H18ClN3O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0524416
|
US8802673, 46
Show/Hide
|
C19H19N3O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0539099
|
US8802673, 171
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0868674
|
US9181230, 14
Show/Hide
|
C19H17F2N3O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0406847
|
US9416127, 22
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0484093
|
US11697636, Example 179
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0551901
|
US10501411, Example 56
Show/Hide
|
C17H16Cl2N2O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0555965
|
US10501411, Example 233
Show/Hide
|
C20H19N3O2S
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0524421
|
US8802673, 147
Show/Hide
|
C18H18N4O2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0493420
|
US9416127, 29
Show/Hide
|
C20H19F2N5O3
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0474481
|
US9029370, 68
Show/Hide
|
C16H16BrClN4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0538901
|
US9029370, 77
Show/Hide
|
C19H20F3N3O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0919298
|
US9029370, 1
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0530371
|
US9181230, 39
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0902147
|
US9181230, 28
Show/Hide
|
C20H18N4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0902148
|
US9181230, 31
Show/Hide
|
C19H18FN3O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0939770
|
US9181230, 3
Show/Hide
|
C19H18ClN3O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0405859
|
US11697636, Example 147
Show/Hide
|
C17H16Cl2N2O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0484081
|
US10501411, Example 292
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0499843
|
US9029370, 13
Show/Hide
|
C20H18F2N4O2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0384786
|
US8802673, 149
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0442876
|
US8802673, 38
Show/Hide
|
C15H16ClN3O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0490532
|
US8802673, 113
Show/Hide
|
C19H20N4O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0520649
|
US8802673, 5
Show/Hide
|
C15H16ClN3O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0868677
|
US9181230, 41
Show/Hide
|
C19H17F2N3O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0518695
|
US9416127, 26
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0561207
|
US9416127, 23
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0393349
|
US10501411, Example 46
Show/Hide
|
C19H21FN2O2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0393350
|
US11697636, Example 149
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0404995
|
US10501411, Example 18
Show/Hide
|
C18H17F3N2O
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0441571
|
US9029370, 18
Show/Hide
|
C20H18ClFN4O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0441604
|
US9029370, 78
Show/Hide
|
C19H20F3N3O3
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0468227
|
US9029370, 20
Show/Hide
|
C16H16Cl2N4O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0488839
|
US9029370, 55
Show/Hide
|
C16H16Cl2N4O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0515465
|
US9029370, 5
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0529262
|
US9029370, 6
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0529263
|
US9029370, 26
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0899550
|
US9029370, 2
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0491093
|
US8802673, 53
Show/Hide
|
C19H18BrN3O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0503586
|
US8802673, 47
Show/Hide
|
C19H18ClN3O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0865216
|
US9181230, 40
Show/Hide
|
C19H17F2N3O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0879626
|
US9181230, 20
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0913787
|
US9181230, 4
Show/Hide
|
C19H18FN3O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0419343
|
US9416127, 1
Show/Hide
|
C19H19N5O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0425534
|
US10501411, Example 213
Show/Hide
|
C25H23ClN2O5
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0486274
|
US10501411, Example 291
Show/Hide
|
C18H18F3N3O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0468231
|
US9029370, 96
Show/Hide
|
C21H19ClF2N4O3
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0488841
|
US9029370, 82
Show/Hide
|
C21H17F3N4O4
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0553587
|
US9416127, 24
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0561196
|
US9416127, 17
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0404997
|
US10501411, Example 44
Show/Hide
|
C16H17ClN4O
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0423318
|
US10501411, Example 27
Show/Hide
|
C18H18F3N3O
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0512888
|
US10501411, Example 124
Show/Hide
|
C19H20F2N2O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0518652
|
US10501411, Example 3
Show/Hide
|
C17H17Cl2N3O
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0474480
|
US9029370, 63
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0488318
|
US9029370, 19
Show/Hide
|
C16H16Cl2N4O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0488840
|
US9029370, 75
Show/Hide
|
C21H19F3N4O3
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0449984
|
US8802673, 69
Show/Hide
|
C15H16ClN3O
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0491097
|
US8802673, 85
Show/Hide
|
C17H20BrN3O
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0928984
|
US9181230, 43
Show/Hide
|
C17H16FN3O
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0481228
|
US9416127, 20
Show/Hide
|
C20H21N5O3
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0493418
|
US9416127, 25
Show/Hide
|
C20H21N5O3
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0544344
|
US9416127, 8
Show/Hide
|
C19H19N5O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0495812
|
US10501411, Example 123
Show/Hide
|
C20H21F3N2O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0441928
|
US9029370, 7
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0524299
|
US9029370, 37
Show/Hide
|
C16H16BrClN4O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0524300
|
US9029370, 53
Show/Hide
|
C17H16ClF3N4O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0533136
|
US9029370, 41
Show/Hide
|
C17H18Cl2N4O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0553386
|
US9029370, 64
Show/Hide
|
C16H16Cl2N4O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0443849
|
US8802673, 11
Show/Hide
|
C16H16F3N3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0519045
|
US8802673, 10
Show/Hide
|
C15H16BrN3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0519050
|
US8802673, 84
Show/Hide
|
C17H20ClN3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0438865
|
US9181230, 19
Show/Hide
|
C19H18FN3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0865215
|
US9181230, 23
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0545134
|
US9416127, 2
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0387675
|
US10501411, Example 8
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0516931
|
US10501411, Example 5
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0468230
|
US9029370, 76
Show/Hide
|
C21H19F3N4O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0499848
|
US9029370, 67
Show/Hide
|
C16H16BrClN4O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0503631
|
US9029370, 3
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0506938
|
US9029370, 46
Show/Hide
|
C19H19ClN4O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0542941
|
US9029370, 14
Show/Hide
|
C16H16Cl2N4O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0400449
|
US8802673, 161
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0516796
|
US8802673, 188
Show/Hide
|
C16H16F4N4O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0536190
|
US8802673, 170
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0910427
|
US9181230, 42
Show/Hide
|
C18H17ClN4O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0930207
|
US9181230, 33
Show/Hide
|
C20H17FN4O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0545113
|
US9416127, 19
Show/Hide
|
C20H21N5O3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0470708
|
US10501411, Example 223
Show/Hide
|
C19H20F3N3O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0478329
|
US10501411, Example 53
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0544394
|
US10501411, Example 96
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0488316
|
US9029370, 4
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0503634
|
US9029370, 31
Show/Hide
|
C20H18ClFN4O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0518578
|
US9029370, 29
Show/Hide
|
C20H18ClFN4O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0553385
|
US9029370, 9
Show/Hide
|
C16H16ClFN4O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0500138
|
US8802673, 195
Show/Hide
|
C17H19FN4O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0509209
|
US8802673, 148
Show/Hide
|
C18H18N4O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0553826
|
US8802673, 17
Show/Hide
|
C17H20N4O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0441068
|
US9181230, 35
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0405853
|
US10501411, Example 52
Show/Hide
|
C19H22N2O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0423322
|
US10501411, Example 109
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0480811
|
US10501411, Example 77
Show/Hide
|
C17H16ClFN2O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0484102
|
US10501411, Example 31
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0548066
|
US10501411, Example 130
Show/Hide
|
C19H18ClF3N2O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0474482
|
US9029370, 71
Show/Hide
|
C19H17F3N4O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0499889
|
US9029370, 50
Show/Hide
|
C17H16ClF3N4O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0516231
|
US9029370, 61
Show/Hide
|
C19H17BrF2N4O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0516792
|
US9029370, 59
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0516793
|
US9029370, 73
Show/Hide
|
C20H21FN4O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0413263
|
US9416127, 32
Show/Hide
|
C20H19F2N5O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0481229
|
US9416127, 21
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0533139
|
US9029370, 72
Show/Hide
|
C19H17F3N4O3
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0565578
|
US9029370, 104
Show/Hide
|
C20H18F3N5O3
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0928189
|
US9181230, 32
Show/Hide
|
C20H18N4O
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0929265
|
US9181230, 6
Show/Hide
|
C20H18N4O
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0537359
|
US9416127, 35
Show/Hide
|
C20H21N5O
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0491877
|
US10501411, Example 126
Show/Hide
|
C19H20Cl2N2O2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0516910
|
US10501411, Example 47
Show/Hide
|
C18H19FN2O2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0506775
|
US9029370, 22
Show/Hide
|
C20H18F2N4O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0506781
|
US9029370, 56
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0520270
|
US9029370, 47
Show/Hide
|
C19H17ClF2N4O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0384789
|
US8802673, 162
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0491106
|
US8802673, 184
Show/Hide
|
C16H16ClF3N4O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0519047
|
US8802673, 26
Show/Hide
|
C17H16ClN3OS
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0541879
|
US8802673, 21
Show/Hide
|
C17H22N4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0512215
|
US9181230, 18
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0387656
|
US10501411, Example 83
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0536957
|
US11697636, Example 150
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0539899
|
US10501411, Example 101
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0540193
|
US10501411, Example 268
Show/Hide
|
C18H18F3N3O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0548089
|
US10501411, Example 303
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0506780
|
US9029370, 49
Show/Hide
|
C17H16ClF3N4O2
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0491107
|
US8802673, 194
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0520647
|
US8802673, 187
Show/Hide
|
C16H17F3N4O2
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0387654
|
US10501411, Example 54
Show/Hide
|
C19H18N2O
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0423323
|
US10501411, Example 110
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0429137
|
US10501411, Example 15
Show/Hide
|
C17H17FN2O2
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0488322
|
US9029370, 79
Show/Hide
|
C17H15FN4O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0506940
|
US9029370, 48
Show/Hide
|
C19H17ClF2N4O3
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0520648
|
US8802673, 203
Show/Hide
|
C16H16ClF3N4O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0910426
|
US9181230, 30
Show/Hide
|
C20H19FN4O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0481210
|
US10501411, Example 299
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0486679
|
US10501411, Example 23
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0556581
|
US9029370, 45
Show/Hide
|
C19H19ClN4O3
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0556583
|
US9029370, 86
Show/Hide
|
C21H19F3N4O3
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0442891
|
US8802673, 42
Show/Hide
|
C16H16F3N3O
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0503589
|
US8802673, 57
Show/Hide
|
C15H15BrFN3O
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0865217
|
US9181230, 46
Show/Hide
|
C16H14F3N3O
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0539161
|
US9029370, 34
Show/Hide
|
C17H16Cl2N2O2
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0553387
|
US9029370, 89
Show/Hide
|
C18H20FN3O3
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0491098
|
US8802673, 86
Show/Hide
|
C17H20N4O
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0550088
|
US8802673, 76
Show/Hide
|
C16H18BrN3O
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0500141
|
US8802673, 119
Show/Hide
|
C17H19FN4O
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0521300
|
US8802673, 192
Show/Hide
|
C17H19FN4O
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0451533
|
US10501411, Example 249
Show/Hide
|
C20H19N3O3
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0488843
|
US9029370, 109
Show/Hide
|
C21H17ClFN5O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0542939
|
US9029370, 8
Show/Hide
|
C16H16ClFN4O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0542940
|
US9029370, 12
Show/Hide
|
C20H18F2N4O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0442132
|
US8802673, 40
Show/Hide
|
C15H15ClFN3O
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0442135
|
US8802673, 205
Show/Hide
|
C14H15ClN4O
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0442895
|
US8802673, 80
Show/Hide
|
C16H18ClN3O
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0524404
|
US8802673, 163
Show/Hide
|
C19H20N4O
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0539097
|
US8802673, 110
Show/Hide
|
C18H22N4O
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0419408
|
US10501411, Example 206
Show/Hide
|
C23H21ClN2O3
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0384785
|
US8802673, 141
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0509208
|
US8802673, 142
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0521217
|
US8802673, 64
Show/Hide
|
C16H18BrN3O
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0953394
|
US9181230, 38
Show/Hide
|
C18H17ClN4O
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0518693
|
US9416127, 7
Show/Hide
|
C20H21N5O2
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0515676
|
US10501411, Example 261
Show/Hide
|
C19H19F3N2O
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0537492
|
US10501411, Example 107
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0538898
|
US9029370, 27
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0442958
|
US8802673, 177
Show/Hide
|
C18H18N4O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0450192
|
US8802673, 15
Show/Hide
|
C16H20N4O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0520283
|
US8802673, 98
Show/Hide
|
C17H19FN4O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0531662
|
US8802673, 131
Show/Hide
|
C14H14ClFN4O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0531313
|
US10501411, Example 7
Show/Hide
|
C17H17Cl2N3O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0538899
|
US9029370, 32
Show/Hide
|
C20H18ClFN4O2
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0554845
|
US9029370, 38
Show/Hide
|
C16H16Cl2N4O
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0499823
|
US8802673, 97
Show/Hide
|
C16H19FN4O
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0466478
|
US9029370, 39
Show/Hide
|
C19H19FN4O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0551020
|
US9029370, 54
Show/Hide
|
C17H16ClF3N4O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0503699
|
US8802673, 127
Show/Hide
|
C14H14BrFN4O
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0539102
|
US8802673, 208
Show/Hide
|
C16H16F4N4O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0488317
|
US9029370, 16
Show/Hide
|
C19H19FN4O2
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0515466
|
US9029370, 62
Show/Hide
|
C18H16F2N4O2
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0554637
|
US9029370, 74
Show/Hide
|
C20H21FN4O3
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0442134
|
US8802673, 190
Show/Hide
|
C17H19FN4O
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0491108
|
US8802673, 197
Show/Hide
|
C15H14F4N4O
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0441930
|
US9029370, 24
Show/Hide
|
C17H17ClFN3O3
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0506774
|
US9029370, 21
Show/Hide
|
C20H18F2N4O2
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0551022
|
US9029370, 105
Show/Hide
|
C21H18ClN5O2
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0442942
|
US8802673, 209
Show/Hide
|
C16H15F5N4O2
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0531765
|
US8802673, 202
Show/Hide
|
C14H14Cl2N4O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0535952
|
US8802673, 101
Show/Hide
|
C17H21FN4O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0539232
|
US9181230, 17
Show/Hide
|
C18H16FN3O2
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0868681
|
US9181230, 47
Show/Hide
|
C15H14ClN3O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0868682
|
US9181230, 49
Show/Hide
|
C16H14F3N3O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0943110
|
US9181230, 2
Show/Hide
|
C17H16ClN3O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0406824
|
US9416127, 34
Show/Hide
|
C19H19N5O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0493481
|
US9416127, 30
Show/Hide
|
C20H21N5O3
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0393346
|
US10501411, Example 6
Show/Hide
|
C17H19N3O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0512889
|
US11697636, Example 178
Show/Hide
|
C19H20F3N3O2
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0451904
|
US9029370, 10
Show/Hide
|
C17H16F4N4O2
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0474483
|
US9029370, 94
Show/Hide
|
C18H20ClN3O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0503635
|
US9029370, 66
Show/Hide
|
C17H16BrN5O2
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0514621
|
US9029370, 85
Show/Hide
|
C18H20FN3O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0555915
|
US9029370, 95
Show/Hide
|
C18H20ClN3O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0555390
|
US8802673, 7
Show/Hide
|
C14H15BrN4O
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0576484
|
US10501411, Example 42
Show/Hide
|
C16H16ClN3O
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0451905
|
US9029370, 25
Show/Hide
|
C17H17ClFN3O3
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0514622
|
US9029370, 88
Show/Hide
|
C18H20FN3O3
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0471188
|
US8802673, 117
Show/Hide
|
C16H19FN4O
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0529249
|
US8802673, 145
Show/Hide
|
C16H16F4N4O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0419405
|
US9181230, 25
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0553281
|
US9416127, 28
Show/Hide
|
C20H18F3N5O3
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0491900
|
US10501411, Example 205
Show/Hide
|
C18H18F3N3O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0466964
|
US9029370, 11
Show/Hide
|
C17H16F4N4O2
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0484453
|
US8802673, 94
Show/Hide
|
C14H15BrN4O
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0551298
|
US8802673, 172
Show/Hide
|
C16H17F3N4O2
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0423321
|
US10501411, Example 80
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0491889
|
US10501411, Example 19
Show/Hide
|
C17H16Cl2N2O
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0538891
|
US9029370, 84
Show/Hide
|
C18H20FN3O3
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0450196
|
US8802673, 124
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0386669
|
US10501411, Example 100
Show/Hide
|
C18H18ClFN2O
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0468229
|
US9029370, 65
Show/Hide
|
C17H16BrN5O2
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0484454
|
US8802673, 137
Show/Hide
|
C16H17F3N4O2
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0484441
|
US10501411, Example 222
Show/Hide
|
C18H18F3N3O3
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0549961
|
US9029370, 58
Show/Hide
|
C19H19BrN4O3
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0491109
|
US8802673, 204
Show/Hide
|
C15H14ClF3N4O
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0503590
|
US8802673, 112
Show/Hide
|
C17H22N4
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0524425
|
US8802673, 193
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0528997
|
US8802673, 118
Show/Hide
|
C17H19FN4O
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0488377
|
US10501411, Example 97
Show/Hide
|
C20H24N2O2
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0450169
|
US9029370, 57
Show/Hide
|
C19H19BrN4O3
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0535954
|
US8802673, 116
Show/Hide
|
C16H19FN4O
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0419337
|
US10501411, Example 200
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0515740
|
US10501411, Example 91
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0450198
|
US8802673, 126
Show/Hide
|
C14H14BrFN4O
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0566202
|
US8802673, 39
Show/Hide
|
C16H19N3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0531620
|
US9181230, 34
Show/Hide
|
C18H16FN3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0868679
|
US9181230, 44
Show/Hide
|
C17H16FN3O
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0910425
|
US9181230, 37
Show/Hide
|
C18H17ClN4O
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0413259
|
US10501411, Example 211
Show/Hide
|
C26H26N2O5
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0515643
|
US10501411, Example 129
Show/Hide
|
C20H22N2O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0512150
|
US8802673, 104
Show/Hide
|
C14H15ClN4O
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0386666
|
US10501411, Example 85
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0513442
|
US10501411, Example 98
Show/Hide
|
C19H19F3N2O
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0553956
|
US10501411, Example 43
Show/Hide
|
C16H16ClN3O
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0512019
|
US9029370, 138
Show/Hide
|
C18H20FN3O3
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0442136
|
US8802673, 211
Show/Hide
|
C16H16ClF3N4O2
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0442874
|
US8802673, 34
Show/Hide
|
C18H21ClN2O
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0503700
|
US8802673, 144
Show/Hide
|
C16H16F4N4O2
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0530405
|
US8802673, 29
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0468228
|
US9029370, 40
Show/Hide
|
C17H19ClN4O2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0471189
|
US8802673, 129
Show/Hide
|
C17H21FN4O
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0484467
|
US8802673, 207
Show/Hide
|
C16H16F4N4O2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0503715
|
US8802673, 178
Show/Hide
|
C16H17F3N4O
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0555964
|
US10501411, Example 231
Show/Hide
|
C20H19N3O2S
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0488838
|
US9029370, 44
Show/Hide
|
C19H19FN4O3
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0442896
|
US8802673, 103
Show/Hide
|
C14H15ClN4O
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0516775
|
US8802673, 173
Show/Hide
|
C15H15F3N4O
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0535953
|
US8802673, 111
Show/Hide
|
C18H22N4O
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0959316
|
US9181230, 5
Show/Hide
|
C18H17ClN4O
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0450197
|
US8802673, 125
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0539098
|
US8802673, 146
Show/Hide
|
C17H22N4O
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0493419
|
US9416127, 36
Show/Hide
|
C18H17BrN6O2
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0539900
|
US10501411, Example 108
Show/Hide
|
C20H18ClN3O
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0512149
|
US8802673, 102
Show/Hide
|
C14H14BrFN4O
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0512152
|
US8802673, 132
Show/Hide
|
C16H19FN4O2
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0520280
|
US8802673, 79
Show/Hide
|
C17H19ClN2O
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0539100
|
US8802673, 179
Show/Hide
|
C15H16F2N4O2
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0553831
|
US8802673, 210
Show/Hide
|
C14H14ClFN4O
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0450282
|
US9029370, 92
Show/Hide
|
C18H20ClN3O3
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0512018
|
US9029370, 134
Show/Hide
|
C19H16F4N6O2
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0512927
|
US10501411, Example 55
Show/Hide
|
C18H17N3O
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0556174
|
US10501411, Example 69
Show/Hide
|
C17H16ClFN2O
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0513417
|
US9029370, 52
Show/Hide
|
C16H15ClF3N5O2
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0500140
|
US8802673, 59
Show/Hide
|
C16H16ClFN2O
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0503591
|
US8802673, 128
Show/Hide
|
C17H21FN4O
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0539101
|
US8802673, 196
Show/Hide
|
C15H14F4N4O
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0413264
|
US9416127, 33
Show/Hide
|
C20H19F2N5O2
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0512887
|
US10501411, Example 74
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0515677
|
US10501411, Example 270
Show/Hide
|
C16H15Cl2N3O2
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0538890
|
US9029370, 80
Show/Hide
|
C17H15FN4O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0499824
|
US8802673, 107
Show/Hide
|
C17H22N4O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0503587
|
US8802673, 50
Show/Hide
|
C18H17ClN4O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0520282
|
US8802673, 93
Show/Hide
|
C17H22N4O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0524443
|
US8802673, 206
Show/Hide
|
C14H15ClN4O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0405863
|
US10501411, Example 204
Show/Hide
|
C18H18F3N3O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0478763
|
US10501411, Example 221
Show/Hide
|
C16H15Cl2N3O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0442130
|
US8802673, 30
Show/Hide
|
C17H18Cl2N2O
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0471190
|
US8802673, 130
Show/Hide
|
C14H14ClFN4O
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0528999
|
US8802673, 136
Show/Hide
|
C16H17F3N4O2
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0425525
|
US10501411, Example 86
Show/Hide
|
C16H16ClN3O
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0425526
|
US10501411, Example 87
Show/Hide
|
C16H16BrN3O
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0561904
|
US9029370, 103
Show/Hide
|
C21H18ClN5O2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0535955
|
US8802673, 133
Show/Hide
|
C16H19FN4O2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0387673
|
US10501411, Example 262
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0413446
|
US10501411, Example 192
Show/Hide
|
C24H24N2O3
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0491892
|
US10501411, Example 88
Show/Hide
|
C18H19FN2O2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0557330
|
US9029370, 91
Show/Hide
|
C18H20ClN3O3
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0520659
|
US8802673, 100
Show/Hide
|
C16H19FN4O2
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0550264
|
US8802673, 77
Show/Hide
|
C15H15ClFN3O
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0541863
|
US9029370, 108
Show/Hide
|
C21H17F2N5O2
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0521211
|
US8802673, 18
Show/Hide
|
C15H18N4O
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0405834
|
US10501411, Example 143
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0443850
|
US8802673, 12
Show/Hide
|
C15H18N4O2
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0557247
|
US10501411, Example 57
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0506783
|
US9029370, 70
Show/Hide
|
C16H15BrF3N5O2
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0530404
|
US8802673, 19
Show/Hide
|
C15H15F3N4O
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0413211
|
US10501411, Example 1
Show/Hide
|
C22H29N3O
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0512928
|
US10501411, Example 73
Show/Hide
|
C19H19N5O
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0503593
|
US8802673, 135
Show/Hide
|
C15H14F4N4O
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0536243
|
US8802673, 95
Show/Hide
|
C15H15F3N4O
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0405864
|
US10501411, Example 214
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0442897
|
US8802673, 120
Show/Hide
|
C15H17BrN4O
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0450195
|
US8802673, 121
Show/Hide
|
C15H14F4N4O
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0520661
|
US8802673, 180
Show/Hide
|
C15H17ClN4O2
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0520658
|
US8802673, 74
Show/Hide
|
C18H22N4O
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0491893
|
US10501411, Example 89
Show/Hide
|
C18H18F3N3O2
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0548074
|
US10501411, Example 219
Show/Hide
|
C16H15Cl2N3O2
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0563898
|
US9029370, 83
Show/Hide
|
C17H15F4N3O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0491105
|
US8802673, 175
Show/Hide
|
C19H17ClF2N6O3
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0516909
|
US10501411, Example 283
Show/Hide
|
C17H16F3N3O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0500336
|
US8802673, 45
Show/Hide
|
C17H19BrN2O
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0516774
|
US8802673, 160
Show/Hide
|
C15H18N4O
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0529271
|
US8802673, 96
Show/Hide
|
C14H14ClFN4O
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
|
CP0516915
|
US10501411, Example 137
Show/Hide
|
C21H26N2O
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
|
CP0450283
|
US9029370, 106
Show/Hide
|
C17H14ClFN4O2
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0488324
|
US9029370, 99
Show/Hide
|
C17H15ClN4O2
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0386658
|
US10501411, Example 11
Show/Hide
|
C17H18N2O2
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0468233
|
US9029370, 137
Show/Hide
|
C16H14F4N4O2
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0533137
|
US9029370, 51
Show/Hide
|
C16H15ClF3N5O2
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0515636
|
US10501411, Example 271
Show/Hide
|
C16H15Cl2N3O2
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0548062
|
US10501411, Example 78
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0553588
|
US9416127, 27
Show/Hide
|
C20H18F3N5O3
|
1
|
| 1 |
Ki = 6.8 nM
|
|
|
|
CP0520660
|
US8802673, 134
Show/Hide
|
C15H14F4N4O
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0541869
|
US9029370, 127
Show/Hide
|
C19H16F4N6O2
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0529272
|
US8802673, 153
Show/Hide
|
C15H15F3N4O
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0536242
|
US8802673, 87
Show/Hide
|
C18H22N4O
|
1
|
| 1 |
Ki = 7.1 nM
|
|
|
|
CP0413465
|
US10501411, Example 304
Show/Hide
|
C18H21N3O2
|
1
|
| 1 |
Ki = 7.1 nM
|
|
|
|
CP0488325
|
US9029370, 129
Show/Hide
|
C19H16F4N6O2
|
1
|
| 1 |
Ki = 7.3 nM
|
|
|
|
CP0468232
|
US9029370, 111
Show/Hide
|
C21H18FN5O2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0563897
|
US9029370, 15
Show/Hide
|
C19H19FN4O2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0490529
|
US8802673, 67
Show/Hide
|
C15H16ClN3O
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0518650
|
US10501411, Example 293
Show/Hide
|
C18H21N3O2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0535911
|
US9029370, 130
Show/Hide
|
C20H17F4N5O2
|
1
|
| 1 |
Ki = 7.5 nM
|
|
|
|
CP0535912
|
US9029370, 136
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
Ki = 7.5 nM
|
|
|
|
CP0425524
|
US10501411, Example 79
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
Ki = 7.5 nM
|
|
|
|
CP0512151
|
US8802673, 109
Show/Hide
|
C14H15BrN4O
|
1
|
| 1 |
Ki = 7.7 nM
|
|
|
|
CP0484095
|
US10501411, Example 209
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0530408
|
US8802673, 115
Show/Hide
|
C18H18N4O2
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0536245
|
US8802673, 122
Show/Hide
|
C17H22N4O2
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0561011
|
US9029370, 132
Show/Hide
|
C19H16F4N6O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0442941
|
US8802673, 201
Show/Hide
|
C15H15F3N4O
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0530622
|
US8802673, 88
Show/Hide
|
C17H22N4O
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0386659
|
US10501411, Example 13
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0405854
|
US10501411, Example 84
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0499822
|
US8802673, 91
Show/Hide
|
C14H15BrN4O
|
1
|
| 1 |
Ki = 8.1 nM
|
|
|
|
CP0488321
|
US9029370, 35
Show/Hide
|
C16H15Cl2N3O2
|
1
|
| 1 |
Ki = 8.2 nM
|
|
|
|
CP0423948
|
US10501411, Example 275
Show/Hide
|
C19H22N2O3
|
1
|
| 1 |
Ki = 8.2 nM
|
|
|
|
CP0544299
|
US10501411, Example 285
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 8.2 nM
|
|
|
|
CP0548106
|
US11697636, Example 154
Show/Hide
|
C19H20Cl2N2O
|
1
|
| 1 |
Ki = 8.2 nM
|
|
|
|
CP0387684
|
US10501411, Example 17
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 8.3 nM
|
|
|
|
CP0491090
|
US8802673, 181
Show/Hide
|
C15H15N5O
|
1
|
| 1 |
Ki = 8.4 nM
|
|
|
|
CP0506782
|
US9029370, 69
Show/Hide
|
C16H15BrF3N5O2
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0536244
|
US8802673, 106
Show/Hide
|
C17H22N4O
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0472162
|
US11697636, Example 152
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0405836
|
US10501411, Example 202
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0514623
|
US9029370, 110
Show/Hide
|
C21H17F2N5O2
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0514647
|
US9029370, 128
Show/Hide
|
C19H16ClF3N6O2
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0500143
|
US8802673, 174
Show/Hide
|
C19H18F2N6O3
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0520662
|
US8802673, 200
Show/Hide
|
C15H15F3N4O
|
1
|
| 1 |
Ki = 8.9 nM
|
|
|
|
CP0930210
|
US9181230, 7
Show/Hide
|
C16H15BrN4O
|
1
|
| 1 |
Ki = 8.9 nM
|
|
|
|
CP0910994
|
US9181230, 11
Show/Hide
|
C17H15F2N3O
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0566771
|
US9029370, 107
Show/Hide
|
C18H17FN4O3
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0424110
|
US8802673, 156
Show/Hide
|
C15H18N4O
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0443853
|
US8802673, 68
Show/Hide
|
C16H20N4O
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0491091
|
US8802673, 183
Show/Hide
|
C16H20N4O3
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0462835
|
US9029370, 133
Show/Hide
|
C17H14ClFN4O2
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0512890
|
US10501411, Example 113
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0443856
|
US8802673, 73
Show/Hide
|
C18H24N4O
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0491086
|
US8802673, 154
Show/Hide
|
C15H15F3N4O
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0550087
|
US8802673, 35
Show/Hide
|
C17H18ClFN2O
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0554846
|
US9029370, 81
Show/Hide
|
C17H15FN4O2
|
1
|
| 1 |
Ki = 9.7 nM
|
|
|
|
CP0550187
|
US9181230, 36
Show/Hide
|
C18H17FN4O
|
1
|
| 1 |
Ki = 9.7 nM
|
|
|
|
CP0484080
|
US10501411, Example 269
Show/Hide
|
C18H18F3N3O3
|
1
|
| 1 |
Ki = 9.9 nM
|
|
|
|
CP0910995
|
US9181230, 16
Show/Hide
|
C19H21N3O
|
1
|
| 1 |
Ki = 10.1 nM
|
|
|
|
CP0488375
|
US10501411, Example 35
Show/Hide
|
C25H25ClN2O
|
1
|
| 1 |
Ki = 10.3 nM
|
|
|
|
CP0450281
|
US9029370, 87
Show/Hide
|
C17H15F4N3O2
|
1
|
| 1 |
Ki = 10.5 nM
|
|
|
|
CP0466882
|
US9029370, 135
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
Ki = 10.5 nM
|
|
|
|
CP0556172
|
US11697636, Example 155
Show/Hide
|
C20H21F3N2O
|
1
|
| 1 |
Ki = 10.7 nM
|
|
|
|
CP0393351
|
US10501411, Example 102
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 10.8 nM
|
|
|
|
CP0509210
|
US8802673, 165
Show/Hide
|
C18H21N3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0405000
|
US10501411, Example 191
Show/Hide
|
C19H20F3N3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0512923
|
US11697636, Example 151
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0413218
|
US10501411, Example 26
Show/Hide
|
C16H17ClN4O
|
1
|
| 1 |
Ki = 11.2 nM
|
|
|
|
CP0449985
|
US8802673, 105
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
Ki = 11.6 nM
|
|
|
|
CP0443855
|
US8802673, 71
Show/Hide
|
C17H20ClN3O2
|
1
|
| 1 |
Ki = 11.8 nM
|
|
|
|
CP0519046
|
US8802673, 24
Show/Hide
|
C18H19F3N2O
|
1
|
| 1 |
Ki = 11.9 nM
|
|
|
|
CP0556585
|
US9029370, 100
Show/Hide
|
C17H15ClN4O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0438896
|
US9181230, 52
Show/Hide
|
C18H19N3O3
|
1
|
| 1 |
Ki = 12.1 nM
|
|
|
|
CP0470194
|
US8802673, 108
Show/Hide
|
C14H15BrN4O
|
1
|
| 1 |
Ki = 12.2 nM
|
|
|
|
CP0530403
|
US8802673, 14
Show/Hide
|
C14H15FN4O
|
1
|
| 1 |
Ki = 12.2 nM
|
|
|
|
CP0486058
|
US8802673, 25
Show/Hide
|
C18H19F3N2O2
|
1
|
| 1 |
Ki = 12.4 nM
|
|
|
|
CP0902151
|
US9181230, 51
Show/Hide
|
C17H20N4O2
|
1
|
| 1 |
Ki = 12.5 nM
|
|
|
|
CP0515644
|
US10501411, Example 142
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 12.6 nM
|
|
|
|
CP0405866
|
US10501411, Example 281
Show/Hide
|
C17H17Cl2N3O
|
1
|
| 1 |
Ki = 12.8 nM
|
|
|
|
CP0490769
|
US10501411, Example 284
Show/Hide
|
C17H16F3N3O2
|
1
|
| 1 |
Ki = 12.8 nM
|
|
|
|
CP0512994
|
US9416127, 31
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0513443
|
US10501411, Example 99
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0553390
|
US8802673, 65
Show/Hide
|
C17H18N2O3
|
1
|
| 1 |
Ki = 13.1 nM
|
|
|
|
CP0484103
|
US10501411, Example 45
Show/Hide
|
C17H22F2N2O2
|
1
|
| 1 |
Ki = 13.1 nM
|
|
|
|
CP0384787
|
US8802673, 157
Show/Hide
|
C15H18N4O
|
1
|
| 1 |
Ki = 13.2 nM
|
|
|
|
CP0442943
|
US8802673, 6
Show/Hide
|
C14H15ClN4O
|
1
|
| 1 |
Ki = 13.3 nM
|
|
|
|
CP0536246
|
US8802673, 150
Show/Hide
|
C15H18F2N4O
|
1
|
| 1 |
Ki = 13.4 nM
|
|
|
|
CP0413447
|
US10501411, Example 195
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
Ki = 13.5 nM
|
|
|
|
CP0942245
|
US9181230, 10
Show/Hide
|
C17H16FN3O
|
1
|
| 1 |
Ki = 13.7 nM
|
|
|
|
CP0557327
|
US9029370, 36
Show/Hide
|
C16H15Cl2N3O2
|
1
|
| 1 |
Ki = 13.9 nM
|
|
|
|
CP0512148
|
US8802673, 89
Show/Hide
|
C15H17BrN4O
|
1
|
| 1 |
Ki = 13.9 nM
|
|
|
|
CP0488319
|
US9029370, 28
Show/Hide
|
C21H18FN5O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0530407
|
US8802673, 75
Show/Hide
|
C14H15N5O3
|
1
|
| 1 |
Ki = 14.1 nM
|
|
|
|
CP0529250
|
US8802673, 182
Show/Hide
|
C16H20N4O
|
1
|
| 1 |
Ki = 14.4 nM
|
|
|
|
CP0514646
|
US9029370, 121
Show/Hide
|
C18H17FN4O3
|
1
|
| 1 |
Ki = 14.5 nM
|
|
|
|
CP0561161
|
US10501411, Example 240
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 14.6 nM
|
|
|
|
CP0552500
|
US10501411, Example 198
Show/Hide
|
C19H22N2O2
|
1
|
| 1 |
Ki = 14.7 nM
|
|
|
|
CP0441929
|
US9029370, 17
Show/Hide
|
C21H21FN4O2
|
1
|
| 1 |
Ki = 15.1 nM
|
|
|
|
CP0516922
|
US10501411, Example 246
Show/Hide
|
C20H24N2OS
|
1
|
| 1 |
Ki = 15.1 nM
|
|
|
|
CP0481202
|
US10501411, Example 263
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
Ki = 15.2 nM
|
|
|
|
CP0450191
|
US8802673, 3
Show/Hide
|
C20H22ClF3N2
|
1
|
| 1 |
Ki = 15.7 nM
|
|
|
|
CP0557248
|
US10501411, Example 139
Show/Hide
|
C17H16F3N3O
|
1
|
| 1 |
Ki = 15.8 nM
|
|
|
|
CP0515635
|
US10501411, Example 260
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0550089
|
US8802673, 81
Show/Hide
|
C15H17ClN4O
|
1
|
| 1 |
Ki = 16.2 nM
|
|
|
|
CP0531534
|
US10501411, Example 267
Show/Hide
|
C18H20N2O2S
|
1
|
| 1 |
Ki = 16.3 nM
|
|
|
|
CP0499888
|
US9029370, 43
Show/Hide
|
C17H17Cl2N3O
|
1
|
| 1 |
Ki = 16.4 nM
|
|
|
|
CP0484425
|
US10501411, Example 24
Show/Hide
|
C19H19F3N2O
|
1
|
| 1 |
Ki = 16.4 nM
|
|
|
|
CP0488842
|
US9029370, 101
Show/Hide
|
C17H15ClN4O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0530406
|
US8802673, 72
Show/Hide
|
C17H22N4O
|
1
|
| 1 |
Ki = 17.1 nM
|
|
|
|
CP0486273
|
US10501411, Example 280
Show/Hide
|
C17H16F3N3O2
|
1
|
| 1 |
Ki = 17.2 nM
|
|
|
|
CP0495845
|
US10501411, Example 61
Show/Hide
|
C20H21F3N2O
|
1
|
| 1 |
Ki = 17.2 nM
|
|
|
|
CP0503698
|
US8802673, 123
Show/Hide
|
C17H22N4O2
|
1
|
| 1 |
Ki = 17.4 nM
|
|
|
|
CP0419409
|
US10501411, Example 216
Show/Hide
|
C18H20N2O2S
|
1
|
| 1 |
Ki = 17.6 nM
|
|
|
|
CP0425531
|
US10501411, Example 197
Show/Hide
|
C19H22N2O3
|
1
|
| 1 |
Ki = 17.7 nM
|
|
|
|
CP0548081
|
US10501411, Example 297
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0516779
|
US8802673, 9
Show/Hide
|
C17H19ClN2O
|
1
|
| 1 |
Ki = 18.1 nM
|
|
|
|
CP0514637
|
US9029370, 125
Show/Hide
|
C19H16F4N6O2
|
1
|
| 1 |
Ki = 18.2 nM
|
|
|
|
CP0516923
|
US10501411, Example 322
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
Ki = 18.8 nM
|
|
|
|
CP0544404
|
US10501411, Example 144
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
Ki = 18.8 nM
|
|
|
|
CP0488373
|
US10501411, Example 4
Show/Hide
|
C21H23N5O2
|
1
|
| 1 |
Ki = 18.9 nM
|
|
|
|
CP0554037
|
US10501411, Example 225
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 18.9 nM
|
|
|
|
CP0513469
|
US10501411, Example 90
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
Ki = 19.2 nM
|
|
|
|
CP0424108
|
US8802673, 152
Show/Hide
|
C17H21FN4O3
|
1
|
| 1 |
Ki = 19.6 nM
|
|
|
|
CP0491099
|
US8802673, 90
Show/Hide
|
C14H15ClN4O
|
1
|
| 1 |
Ki = 19.6 nM
|
|
|
|
CP0516916
|
US10501411, Example 141
Show/Hide
|
C17H16F3N3O2
|
1
|
| 1 |
Ki = 20.1 nM
|
|
|
|
CP0512620
|
US9029370, 126
Show/Hide
|
C19H16ClF3N6O2
|
1
|
| 1 |
Ki = 20.2 nM
|
|
|
|
CP0386663
|
US10501411, Example 131
Show/Hide
|
C15H19F3N2O2
|
1
|
| 1 |
Ki = 20.8 nM
|
|
|
|
CP0481204
|
US10501411, Example 265
Show/Hide
|
C18H18F3N3O
|
1
|
| 1 |
Ki = 20.9 nM
|
|
|
|
CP0450194
|
US8802673, 114
Show/Hide
|
C17H22N4O
|
1
|
| 1 |
Ki = 21.2 nM
|
|
|
|
CP0497611
|
US10501411, Example 272
Show/Hide
|
C17H16F3N3O2
|
1
|
| 1 |
Ki = 21.4 nM
|
|
|
|
CP0470652
|
US10501411, Example 234
Show/Hide
|
C19H19F3N2O
|
1
|
| 1 |
Ki = 21.7 nM
|
|
|
|
CP0536960
|
US10501411, Example 229
Show/Hide
|
C17H16ClFN2O2
|
1
|
| 1 |
Ki = 21.8 nM
|
|
|
|
CP0539096
|
US8802673, 60
Show/Hide
|
C17H19ClN2O
|
1
|
| 1 |
Ki = 22.2 nM
|
|
|
|
CP0574106
|
US10501411, Example 286
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 22.2 nM
|
|
|
|
CP0548076
|
US10501411, Example 258
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
Ki = 22.5 nM
|
|
|
|
CP0419307
|
US10501411, Example 81
Show/Hide
|
C20H20N4O
|
1
|
| 1 |
Ki = 22.7 nM
|
|
|
|
CP0516917
|
US10501411, Example 145
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
Ki = 22.7 nM
|
|
|
|
CP0490530
|
US8802673, 92
Show/Hide
|
C16H19N5O
|
1
|
| 1 |
Ki = 22.9 nM
|
|
|
|
CP0550485
|
US8802673, 199
Show/Hide
|
C14H15ClN4O
|
1
|
| 1 |
Ki = 23.1 nM
|
|
|
|
CP0553383
|
US9029370, 124
Show/Hide
|
C18H17ClN4O3
|
1
|
| 1 |
Ki = 23.5 nM
|
|
|
|
CP0554659
|
US10501411, Example 92
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 23.8 nM
|
|
|
|
CP0491062
|
US10501411, Example 106
Show/Hide
|
C17H17F2N3O
|
1
|
| 1 |
Ki = 24.8 nM
|
|
|
|
CP0425530
|
US10501411, Example 182
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
Ki = 25.3 nM
|
|
|
|
CP0491899
|
US11697636, Example 176
Show/Hide
|
C20H22Cl2N2O
|
1
|
| 1 |
Ki = 25.3 nM
|
|
|
|
CP0466965
|
US9029370, 23
Show/Hide
|
C21H21FN4O2
|
1
|
| 1 |
Ki = 25.4 nM
|
|
|
|
CP0553384
|
US9029370, 131
Show/Hide
|
C19H16FN7O2
|
1
|
| 1 |
Ki = 25.4 nM
|
|
|
|
CP0484076
|
US10501411, Example 75
Show/Hide
|
C16H15F2N3O
|
1
|
| 1 |
Ki = 25.5 nM
|
|
|
|
CP0393341
|
US10501411, Example 59
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 25.6 nM
|
|
|
|
CP0532976
|
US9029370, 102
Show/Hide
|
C17H15ClN4O2
|
1
|
| 1 |
Ki = 25.9 nM
|
|
|
|
CP0561411
|
US9029370, 112
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
Ki = 25.9 nM
|
|
|
|
CP0530402
|
US8802673, 13
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
Ki = 26.6 nM
|
|
|
|
CP0550263
|
US8802673, 49
Show/Hide
|
C21H17F6N3O
|
1
|
| 1 |
Ki = 26.6 nM
|
|
|
|
CP0386656
|
US10501411, Example 306
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki = 26.6 nM
|
|
|
|
CP0481211
|
US10501411, Example 305
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 26.6 nM
|
|
|
|
CP0425528
|
US10501411, Example 146
Show/Hide
|
C17H16ClFN2O2
|
1
|
| 1 |
Ki = 26.8 nM
|
|
|
|
CP0539095
|
US8802673, 43
Show/Hide
|
C15H16FN3O
|
1
|
| 1 |
Ki = 26.9 nM
|
|
|
|
CP0488374
|
US10501411, Example 34
Show/Hide
|
C24H23ClN2O
|
1
|
| 1 |
Ki = 26.9 nM
|
|
|
|
CP0491897
|
US11697636, Example 167
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 27.1 nM
|
|
|
|
CP0474484
|
US9029370, 98
Show/Hide
|
C17H15ClN4O2
|
1
|
| 1 |
Ki = 27.6 nM
|
|
|
|
CP0521210
|
US8802673, 16
Show/Hide
|
C15H15N5O
|
1
|
| 1 |
Ki = 27.6 nM
|
|
|
|
CP0868680
|
US9181230, 45
Show/Hide
|
C15H15N3O
|
1
|
| 1 |
Ki = 27.7 nM
|
|
|
|
CP0413221
|
US10501411, Example 62
Show/Hide
|
C20H21F3N2O2
|
1
|
| 1 |
Ki = 27.8 nM
|
|
|
|
CP0555547
|
US10501411, Example 288
Show/Hide
|
C18H17N5O2S
|
1
|
| 1 |
Ki = 27.8 nM
|
|
|
|
CP0557328
|
US9029370, 42
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0488314
|
US9029370, 117
Show/Hide
|
C19H21FN4O3
|
1
|
| 1 |
Ki = 28.4 nM
|
|
|
|
CP0539094
|
US8802673, 36
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
Ki = 28.8 nM
|
|
|
|
CP0450284
|
US9029370, 115
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0868675
|
US9181230, 15
Show/Hide
|
C17H16FN3O
|
1
|
| 1 |
Ki = 29.2 nM
|
|
|
|
CP0491894
|
US10501411, Example 105
Show/Hide
|
C21H23F3N2O2
|
1
|
| 1 |
Ki = 29.6 nM
|
|
|
|
CP0491104
|
US8802673, 166
Show/Hide
|
C16H17F3N4O
|
1
|
| 1 |
Ki = 30.1 nM
|
|
|
|
CP0419404
|
US9181230, 22
Show/Hide
|
C19H19FN2O2
|
1
|
| 1 |
Ki = 31.8 nM
|
|
|
|
CP0506777
|
US9029370, 30
Show/Hide
|
C20H18ClFN4O2
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0491895
|
US11697636, Example 158
Show/Hide
|
C21H26N2O2
|
1
|
| 1 |
Ki = 32.6 nM
|
|
|
|
CP0539904
|
US10501411, Example 185
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
Ki = 33.3 nM
|
|
|
|
CP0540643
|
US10501411, Example 235
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 33.4 nM
|
|
|
|
CP0481206
|
US10501411, Example 273
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 34.3 nM
|
|
|
|
CP0484094
|
US10501411, Example 189
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
Ki = 34.3 nM
|
|
|
|
CP0405855
|
US10501411, Example 111
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
Ki = 34.9 nM
|
|
|
|
CP0405833
|
US10501411, Example 138
Show/Hide
|
C18H18F3N3O
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0471183
|
US8802673, 32
Show/Hide
|
C16H18ClN3O
|
1
|
| 1 |
Ki = 35.7 nM
|
|
|
|
CP0491092
|
US8802673, 51
Show/Hide
|
C20H20ClN3O
|
1
|
| 1 |
Ki = 36.3 nM
|
|
|
|
CP0515745
|
US10501411, Example 119
Show/Hide
|
C20H24ClN3O
|
1
|
| 1 |
Ki = 36.5 nM
|
|
|
|
CP0478327
|
US10501411, Example 242
Show/Hide
|
C18H18F3N3O
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0519049
|
US8802673, 56
Show/Hide
|
C16H18BrN3O
|
1
|
| 1 |
Ki = 37.2 nM
|
|
|
|
CP0539093
|
US8802673, 22
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
Ki = 37.5 nM
|
|
|
|
CP0965647
|
US9181230, 1
Show/Hide
|
C17H17N3O
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0513470
|
US10501411, Example 95
Show/Hide
|
C18H21N3O3
|
1
|
| 1 |
Ki = 38.5 nM
|
|
|
|
CP0509207
|
US8802673, 140
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
Ki = 38.6 nM
|
|
|
|
CP0539903
|
US9452980, 148
Show/Hide
|
C16H16ClN3O2
|
1
|
| 1 |
Ki = 39.3 nM
|
|
|
|
CP0387669
|
US10501411, Example 239
Show/Hide
|
C16H17ClN4O
|
1
|
| 1 |
Ki = 39.6 nM
|
|
|
|
CP0386667
|
US10501411, Example 93
Show/Hide
|
C18H17N3OS
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0512911
|
US11697636, Example 161
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 40.3 nM
|
|
|
|
CP0405835
|
US10501411, Example 193
Show/Hide
|
C16H16ClN3O2
|
1
|
| 1 |
Ki = 40.6 nM
|
|
|
|
CP0387685
|
US10501411, Example 38
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
Ki = 40.7 nM
|
|
|
|
CP0542938
|
US9029370, 123
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
Ki = 41.3 nM
|
|
|
|
CP0474477
|
US9029370, 118
Show/Hide
|
C18H19ClN4O3
|
1
|
| 1 |
Ki = 41.6 nM
|
|
|
|
CP0553830
|
US8802673, 198
Show/Hide
|
C15H15F3N4O
|
1
|
| 1 |
Ki = 41.9 nM
|
|
|
|
CP0539905
|
US10501411, Example 220
Show/Hide
|
C22H27ClN2O4
|
1
|
| 1 |
Ki = 43.5 nM
|
|
|
|
CP0478325
|
US10501411, Example 210
Show/Hide
|
C16H16ClN3O2
|
1
|
| 1 |
Ki = 43.6 nM
|
|
|
|
CP0449983
|
US8802673, 27
Show/Hide
|
C16H18BrN3O
|
1
|
| 1 |
Ki = 43.8 nM
|
|
|
|
CP0484079
|
US10501411, Example 259
Show/Hide
|
C19H22N2OS
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0553827
|
US8802673, 31
Show/Hide
|
C17H19FN2O
|
1
|
| 1 |
Ki = 45.2 nM
|
|
|
|
CP0541878
|
US8802673, 20
Show/Hide
|
C18H22N2O2
|
1
|
| 1 |
Ki = 45.3 nM
|
|
|
|
CP0491061
|
US10501411, Example 104
Show/Hide
|
C21H23F3N2O
|
1
|
| 1 |
Ki = 45.4 nM
|
|
|
|
CP0419406
|
US9181230, 53
Show/Hide
|
C17H14F3N3O2
|
1
|
| 1 |
Ki = 46.3 nM
|
|
|
|
CP0471184
|
US8802673, 33
Show/Hide
|
C17H18F3N3O
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0475692
|
US10501411, Example 277
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
Ki = 47.2 nM
|
|
|
|
CP0519675
|
US11697636, Example 175
Show/Hide
|
C21H23F3N2O
|
1
|
| 1 |
Ki = 47.3 nM
|
|
|
|
CP0493123
|
US10501411, Example 310
Show/Hide
|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 47.6 nM
|
|
|
|
CP0544298
|
US9452980, 267
Show/Hide
|
C18H20N2O2S
|
1
|
| 1 |
Ki = 47.6 nM
|
|
|
|
CP0553829
|
US8802673, 151
Show/Hide
|
C17H21FN4O3
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0524304
|
US9029370, 113
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
Ki = 48.1 nM
|
|
|
|
CP0548108
|
US10501411, Example 186
Show/Hide
|
C19H22N2O2
|
1
|
| 1 |
Ki = 48.6 nM
|
|
|
|
CP0548109
|
US10501411, Example 190
Show/Hide
|
C18H20N2O3
|
1
|
| 1 |
Ki = 50.1 nM
|
|
|
|
CP0488371
|
US10501411, Example 298
Show/Hide
|
C19H19N5O2S
|
1
|
| 1 |
Ki = 50.6 nM
|
|
|
|
CP0554134
|
US11697636, Example 180
Show/Hide
|
C17H18FN3O
|
1
|
| 1 |
Ki = 50.7 nM
|
|
|
|
CP0512886
|
US10501411, Example 301
Show/Hide
|
C17H16ClIN2O2
|
1
|
| 1 |
Ki = 50.9 nM
|
|
|
|
CP0519676
|
US10501411, Example 224
Show/Hide
|
C19H20F3N3O2
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0450285
|
US9029370, 116
Show/Hide
|
C17H16ClFN4O3
|
1
|
| 1 |
Ki = 51.2 nM
|
|
|
|
CP0500334
|
US8802673, 23
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
Ki = 51.4 nM
|
|
|
|
CP0469603
|
US10501411, Example 196
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
Ki = 52.4 nM
|
|
|
|
CP0548073
|
US10501411, Example 207
Show/Hide
|
C16H16ClN3O2
|
1
|
| 1 |
Ki = 52.5 nM
|
|
|
|
CP0549629
|
US11697636, Example 183
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
Ki = 52.6 nM
|
|
|
|
CP0429139
|
US10501411, Example 30
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0512930
|
US10501411, Example 117
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
Ki = 53.1 nM
|
|
|
|
CP0426462
|
US8802673, 185
Show/Hide
|
C16H15ClF3N3O
|
1
|
| 1 |
Ki = 54.9 nM
|
|
|
|
CP0387668
|
US10501411, Example 226
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 55.5 nM
|
|
|
|
CP0425522
|
US10501411, Example 37
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 55.6 nM
|
|
|
|
CP0555546
|
US10501411, Example 276
Show/Hide
|
C19H22N2O3
|
1
|
| 1 |
Ki = 55.8 nM
|
|
|
|
CP0554132
|
US11697636, Example 163
Show/Hide
|
C15H15ClN4O
|
1
|
| 1 |
Ki = 57.3 nM
|
|
|
|
CP0488372
|
US10501411, Example 302
Show/Hide
|
C16H17ClN4O2
|
1
|
| 1 |
Ki = 57.4 nM
|
|
|
|
CP0450193
|
US8802673, 61
Show/Hide
|
C15H15Br2N3O
|
1
|
| 1 |
Ki = 59.1 nM
|
|
|
|
CP0531537
|
US10501411, Example 323
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
Ki = 59.2 nM
|
|
|
|
CP0386668
|
US10501411, Example 94
Show/Hide
|
C17H19N3O2
|
1
|
| 1 |
Ki = 60.1 nM
|
|
|
|
CP0413258
|
US10501411, Example 203
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 60.3 nM
|
|
|
|
CP0491898
|
US11697636, Example 169
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
Ki = 60.7 nM
|
|
|
|
CP0481209
|
US10501411, Example 290
Show/Hide
|
C18H17N5O2S
|
1
|
| 1 |
Ki = 60.8 nM
|
|
|
|
CP0491874
|
US10501411, Example 116
Show/Hide
|
C19H22ClN3O
|
1
|
| 1 |
Ki = 60.8 nM
|
|
|
|
CP0870565
|
US9181230, 21
Show/Hide
|
C18H17FN4O2
|
1
|
| 1 |
Ki = 61.7 nM
|
|
|
|
CP0442914
|
US8802673, 138
Show/Hide
|
C17H22N4O3
|
1
|
| 1 |
Ki = 64.1 nM
|
|
|
|
CP0419407
|
US9181230, 55
Show/Hide
|
C17H14F3N3O2
|
1
|
| 1 |
Ki = 64.4 nM
|
|
|
|
CP0561163
|
US10501411, Example 296
Show/Hide
|
C18H19N5O2S
|
1
|
| 1 |
Ki = 64.5 nM
|
|
|
|
CP0561419
|
US9029370, 114
Show/Hide
|
C18H19FN4O3
|
1
|
| 1 |
Ki = 64.9 nM
|
|
|
|
CP0387671
|
US10501411, Example 245
Show/Hide
|
C18H21N3O3
|
1
|
| 1 |
Ki = 64.9 nM
|
|
|
|
CP0548072
|
US11697636, Example 181
Show/Hide
|
C16H16ClN3O
|
1
|
| 1 |
Ki = 66.3 nM
|
|
|
|
CP0442934
|
US8802673, 139
Show/Hide
|
C17H22N4O3
|
1
|
| 1 |
Ki = 66.7 nM
|
|
|
|
CP0490926
|
US10501411, Example 237
Show/Hide
|
C20H24N2OS
|
1
|
| 1 |
Ki = 67.7 nM
|
|
|
|
CP0520279
|
US8802673, 58
Show/Hide
|
C15H15Cl2N3O
|
1
|
| 1 |
Ki = 70.4 nM
|
|
|
|
CP0512910
|
US11697636, Example 153
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 71.5 nM
|
|
|
|
CP0405868
|
US10501411, Example 300
Show/Hide
|
C18H21N3O3
|
1
|
| 1 |
Ki = 72.6 nM
|
|
|
|
CP0557095
|
US8802673, 1
Show/Hide
|
C16H20N4
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0518664
|
US10501411, Example 208
Show/Hide
|
C16H16ClN3O2
|
1
|
| 1 |
Ki = 76.2 nM
|
|
|
|
CP0491888
|
US10501411, Example 307
Show/Hide
|
C17H25N3O2
|
1
|
| 1 |
Ki = 77.8 nM
|
|
|
|
CP0490765
|
US10501411, Example 252
Show/Hide
|
C17H18BrN3O
|
1
|
| 1 |
Ki = 78.3 nM
|
|
|
|
CP0488323
|
US9029370, 97
Show/Hide
|
C17H15ClN4O2
|
1
|
| 1 |
Ki = 82.4 nM
|
|
|
|
CP0425494
|
US10501411, Example 114
Show/Hide
|
C18H21ClN4O
|
1
|
| 1 |
Ki = 83.6 nM
|
|
|
|
CP0484075
|
US10501411, Example 63
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
Ki = 83.7 nM
|
|
|
|
CP0462834
|
US9029370, 119
Show/Hide
|
C18H19FN4O3
|
1
|
| 1 |
Ki = 84.4 nM
|
|
|
|
CP0468226
|
US9029370, 120
Show/Hide
|
C18H19FN4O4
|
1
|
| 1 |
Ki = 85.1 nM
|
|
|
|
CP0480771
|
US11697636, Example 160
Show/Hide
|
C16H17ClN4O
|
1
|
| 1 |
Ki = 85.1 nM
|
|
|
|
CP0516914
|
US11697636, Example 164
Show/Hide
|
C17H19ClN4O
|
1
|
| 1 |
Ki = 87.1 nM
|
|
|
|
CP0413450
|
US10501411, Example 218
Show/Hide
|
C16H16ClN3O2
|
1
|
| 1 |
Ki = 87.2 nM
|
|
|
|
CP0469602
|
US10501411, Example 194
Show/Hide
|
C17H16N4O2
|
1
|
| 1 |
Ki = 98.2 nM
|
|
|
|
CP0539906
|
US10501411, Example 230
Show/Hide
|
C17H16ClFN2O2
|
1
|
| 1 |
Ki = 99.7 nM
|
|
|
|
CP0406784
|
US10501411, Example 29
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
Ki = 102.4 nM
|
|
|
|
CP0500144
|
US8802673, 189
Show/Hide
|
C17H20N4O
|
1
|
| 1 |
Ki = 108.9 nM
|
|
|
|
CP0536241
|
US8802673, 78
Show/Hide
|
C15H18N4O3S
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0509212
|
US8802673, 167
Show/Hide
|
C16H17F3N4O
|
1
|
| 1 |
Ki = 111.5 nM
|
|
|
|
CP0484440
|
US11697636, Example 172
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 112.6 nM
|
|
|
|
CP0512929
|
US10501411, Example 201
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 113.3 nM
|
|
|
|
CP0560152
|
US11697636, Example 177
Show/Hide
|
C22H24N2O
|
1
|
| 1 |
Ki = 114.3 nM
|
|
|
|
CP0544304
|
US10501411, Example 309
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
Ki = 115.9 nM
|
|
|
|
CP0553828
|
US8802673, 48
Show/Hide
|
C20H21N3O
|
1
|
| 1 |
Ki = 121.8 nM
|
|
|
|
CP0516778
|
US8802673, 4
Show/Hide
|
C21H24ClF3N2
|
1
|
| 1 |
Ki = 122.3 nM
|
|
|
|
CP0519668
|
US10501411, Example 64
Show/Hide
|
C26H26N2O2
|
1
|
| 1 |
Ki = 124.1 nM
|
|
|
|
CP0387655
|
US10501411, Example 65
Show/Hide
|
C19H22N2O2
|
1
|
| 1 |
Ki = 124.9 nM
|
|
|
|
CP0472163
|
US11697636, Example 165
Show/Hide
|
C17H16N4O
|
1
|
| 1 |
Ki = 125.6 nM
|
|
|
|
CP0500139
|
US8802673, 37
Show/Hide
|
C16H18FN3O
|
1
|
| 1 |
Ki = 129.2 nM
|
|
|
|
CP0480822
|
US10501411, Example 118
Show/Hide
|
C19H22ClN3O
|
1
|
| 1 |
Ki = 130.5 nM
|
|
|
|
CP0914326
|
US9452980, 76
Show/Hide
|
C18H18N4O
|
1
|
| 1 |
Ki = 136.3 nM
|
|
|
|
CP0552284
|
US10501411, Example 66
Show/Hide
|
C19H19N3O
|
1
|
| 1 |
Ki = 137 nM
|
|
|
|
CP0442959
|
US8802673, 186
Show/Hide
|
C14H14Cl2N4O
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0536959
|
US10501411, Example 188
Show/Hide
|
C17H18N2O2
|
1
|
| 1 |
Ki = 138.4 nM
|
|
|
|
CP0488315
|
US9029370, 122
Show/Hide
|
C18H19ClN4O3
|
1
|
| 1 |
Ki = 140.4 nM
|
|
|
|
CP0387660
|
US11697636, Example 157
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
Ki = 141.8 nM
|
|
|
|
CP0405867
|
US10501411, Example 289
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
Ki = 143.3 nM
|
|
|
|
CP0425535
|
US10501411, Example 279
Show/Hide
|
C20H24N4O2
|
1
|
| 1 |
Ki = 146.3 nM
|
|
|
|
CP0469618
|
US10501411, Example 68
Show/Hide
|
C20H21N3O
|
1
|
| 1 |
Ki = 146.6 nM
|
|
|
|
CP0470651
|
US10501411, Example 232
Show/Hide
|
C21H25N3O4
|
1
|
| 1 |
Ki = 149.9 nM
|
|
|
|
CP0443846
|
US8802673, 176
Show/Hide
|
C14H16N4O
|
1
|
| 1 |
Ki = 151.6 nM
|
|
|
|
CP0423325
|
US11697636, Example 156
Show/Hide
|
C19H21FN2O
|
1
|
| 1 |
Ki = 152.8 nM
|
|
|
|
CP0405832
|
US10501411, Example 136
Show/Hide
|
C18H17ClN2O2
|
1
|
| 1 |
Ki = 152.9 nM
|
|
|
|
CP0554135
|
US11697636, Example 184
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
Ki = 152.9 nM
|
|
|
|
CP0478326
|
US10501411, Example 227
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
Ki = 177.3 nM
|
|
|
|
CP0387672
|
US10501411, Example 248
Show/Hide
|
C17H17F3N4O
|
1
|
| 1 |
Ki = 188.4 nM
|
|
|
|
CP0536958
|
US11697636, Example 171
Show/Hide
|
C19H22ClN3O
|
1
|
| 1 |
Ki = 197.8 nM
|
|
|
|
CP0484442
|
US10501411, Example 228
Show/Hide
|
C22H26N2O4
|
1
|
| 1 |
Ki = 199.2 nM
|
|
|
|
CP0516887
|
US9181230, 54
Show/Hide
|
C17H14F3N3O2
|
1
|
| 1 |
Ki = 203.2 nM
|
|
|
|
CP0536956
|
US10501411, Example 112
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 210.7 nM
|
|
|
|
CP0531533
|
US10501411, Example 236
Show/Hide
|
C19H22N2OS
|
1
|
| 1 |
Ki = 214.3 nM
|
|
|
|
CP0521218
|
US8802673, 66
Show/Hide
|
C19H18BrN3O
|
1
|
| 1 |
Ki = 216.9 nM
|
|
|
|
CP0491896
|
US11697636, Example 162
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 231.2 nM
|
|
|
|
CP0425529
|
US11697636, Example 170
Show/Hide
|
C20H23FN2O
|
1
|
| 1 |
Ki = 234 nM
|
|
|
|
CP0512885
|
US10501411, Example 282
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
Ki = 242.9 nM
|
|
|
|
CP0480769
|
US10501411, Example 140
Show/Hide
|
C16H16ClN3O
|
1
|
| 1 |
Ki = 245.2 nM
|
|
|
|
CP0488370
|
US10501411, Example 244
Show/Hide
|
C18H21N3OS
|
1
|
| 1 |
Ki = 267.9 nM
|
|
|
|
CP0521212
|
US8802673, 41
Show/Hide
|
C16H16F3N3O
|
1
|
| 1 |
Ki = 270.4 nM
|
|
|
|
CP0561164
|
US10501411, Example 316
Show/Hide
|
C19H20F3N3O3
|
1
|
| 1 |
Ki = 272.6 nM
|
|
|
|
CP0560268
|
US8802673, 28
Show/Hide
|
C17H21N3O2
|
1
|
| 1 |
Ki = 276.2 nM
|
|
|
|
CP0516911
|
US10501411, Example 308
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
Ki = 286.8 nM
|
|
|
|
CP0549631
|
US10501411, Example 250
Show/Hide
|
C18H19F3N4O2
|
1
|
| 1 |
Ki = 287.9 nM
|
|
|
|
CP0572282
|
US10501411, Example 264
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
Ki = 297.4 nM
|
|
|
|
CP0406783
|
US10501411, Example 25
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
Ki = 319.5 nM
|
|
|
|
CP0405856
|
US10501411, Example 115
Show/Hide
|
C19H23ClN4O
|
1
|
| 1 |
Ki = 319.9 nM
|
|
|
|
CP0405837
|
US10501411, Example 217
Show/Hide
|
C15H17N3O2S
|
1
|
| 1 |
Ki = 334.6 nM
|
|
|
|
CP0481201
|
US10501411, Example 253
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
Ki = 359.9 nM
|
|
|
|
CP0491095
|
US8802673, 63
Show/Hide
|
C15H15Cl2N3O
|
1
|
| 1 |
Ki = 372.8 nM
|
|
|
|
CP0387661
|
US11697636, Example 166
Show/Hide
|
C18H20FN3O
|
1
|
| 1 |
Ki = 393.6 nM
|
|
|
|
CP0491103
|
US8802673, 143
Show/Hide
|
C14H17BrN4O
|
1
|
| 1 |
Ki = 418.5 nM
|
|
|
|
CP0419305
|
US10501411, Example 28
Show/Hide
|
C16H23N3O
|
1
|
| 1 |
Ki = 433.6 nM
|
|
|
|
CP0554133
|
US11697636, Example 174
Show/Hide
|
C18H21ClN4O
|
1
|
| 1 |
Ki = 437 nM
|
|
|
|
CP0486271
|
US10501411, Example 251
Show/Hide
|
C16H17BrN4O
|
1
|
| 1 |
Ki = 479.8 nM
|
|
|
|
CP0386665
|
US10501411, Example 67
Show/Hide
|
C20H24N2O2
|
1
|
| 1 |
Ki = 498.7 nM
|
|
|
|
CP0484092
|
US10501411, Example 72
Show/Hide
|
C17H17ClN2O2
|
1
|
| 1 |
Ki = 507.3 nM
|
|
|
|
CP0500154
|
US8802673, 70
Show/Hide
|
C18H21ClN2O
|
1
|
| 1 |
Ki = 523.5 nM
|
|
|
|
CP0549632
|
US10501411, Example 22
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
Ki = 526.3 nM
|
|
|
|
CP0478817
|
US10501411, Example 313
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
Ki = 547 nM
|
|
|
|
CP0491087
|
US8802673, 155
Show/Hide
|
C13H16N4O
|
1
|
| 1 |
Ki = 600.2 nM
|
|
|
|
CP0429150
|
US11697636, Example 168
Show/Hide
|
C17H18ClN3O
|
1
|
| 1 |
Ki = 607.8 nM
|
|
|
|
CP0469619
|
US10501411, Example 103
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
Ki = 704.7 nM
|
|
|
|
CP0566259
|
US10501411, Example 82
Show/Hide
|
C16H16FN3O
|
1
|
| 1 |
Ki = 713.1 nM
|
|
|
|
CP0503588
|
US8802673, 55
Show/Hide
|
C15H16FN3O
|
1
|
| 1 |
Ki = 737.6 nM
|
|
|
|
CP0490993
|
US10501411, Example 257
Show/Hide
|
C17H20N4OS
|
1
|
| 1 |
Ki = 785.7 nM
|
|
|
|
CP0470707
|
US11697636, Example 173
Show/Hide
|
C19H22ClN3O
|
1
|
| 1 |
Ki = 823.5 nM
|
|
|
|
CP0481208
|
US10501411, Example 278
Show/Hide
|
C19H24N4O
|
1
|
| 1 |
Ki = 828.6 nM
|
|
|
|
CP0556273
|
US8802673, 158
Show/Hide
|
C16H19N5O2
|
1
|
| 1 |
Ki = 1016.8 nM
|
|
|
|
CP0499605
|
US10501411, Example 238
Show/Hide
|
C16H17ClN4O
|
1
|
| 1 |
Ki = 1118.5 nM
|
|
|
|
CP0419335
|
US10501411, Example 199
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C17H18N2O3
|
1
|
| 1 |
Ki = 1158.2 nM
|
|
|
|
CP0512905
|
US10501411, Example 256
Show/Hide
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C19H23N3O2
|
1
|
| 1 |
Ki = 1166 nM
|
|
|
|
CP0405858
|
US10501411, Example 135
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C19H21F2N3O
|
1
|
| 1 |
Ki = 1265.8 nM
|
|
|
|
CP0537352
|
US10501411, Example 321
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C18H18F3N3O2
|
1
|
| 1 |
Ki = 1313.8 nM
|
|
|
|
CP0384788
|
US8802673, 159
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|
C16H19N5O2
|
1
|
| 1 |
Ki = 1336.2 nM
|
|
|
|
CP0516912
|
US10501411, Example 315
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|
C17H18ClN3O2
|
1
|
| 1 |
Ki = 1350.6 nM
|
|
|
|
CP0516913
|
US10501411, Example 133
Show/Hide
|
C18H19F2N3O
|
1
|
| 1 |
Ki = 1522.8 nM
|
|
|
|
CP0515673
|
US10501411, Example 241
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|
C20H24N4O3
|
1
|
| 1 |
Ki = 1554.6 nM
|
|
|
|
CP0478331
|
US10501411, Example 314
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
Ki = 1885.5 nM
|
|
|
|
CP0488320
|
US9029370, 33
Show/Hide
|
C19H17N5O2
|
1
|
| 1 |
Ki = 2077.1 nM
|
|
|
|
CP0387670
|
US10501411, Example 243
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
Ki = 2119.8 nM
|
|
|
|
CP0425533
|
US10501411, Example 212
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|
C25H24N2O5
|
1
|
| 1 |
Ki = 2498.6 nM
|
|
|
|
CP0405865
|
US10501411, Example 274
Show/Hide
|
C18H22N4O
|
1
|
| 1 |
Ki = 2511.5 nM
|
|
|
|
CP0548075
|
US10501411, Example 254
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|
C18H26N2O3
|
1
|
| 1 |
Ki = 2817.4 nM
|
|
|
|
CP0484057
|
US10501411, Example 215
Show/Hide
|
C24H21ClN2O5
|
1
|
| 1 |
Ki = 2820.1 nM
|
|
|
|
CP0554033
|
US10501411, Example 60
Show/Hide
|
C19H21ClN2O2
|
1
|
| 1 |
Ki = 2826 nM
|
|
|
|
CP0550084
|
US8802673, 2
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|
C17H17BrF3N3
|
1
|
| 1 |
Ki = 4285.7 nM
|
|
|
|
CP0540192
|
US10501411, Example 255
Show/Hide
|
C18H26N2O3
|
1
|
| 1 |
Ki = 5100.5 nM
|
|
|
|
CP0565150
|
US11697636, Example 159
Show/Hide
|
C18H19ClN2O
|
1
|
| 1 |
Ki = 6378.2 nM
|
|
|
|
CP0423324
|
US10501411, Example 132
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|
C18H20FN3O
|
1
|
| 1 |
Ki = 9991.9 nM
|
|
|
|
CP0914173
|
US9181230, 24
Show/Hide
|
C18H23N3O2
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
