Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT03201 , Sialidase-1
Gene Name NEU1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q99519
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT03201
 
Compound ID Compound Name Compound Formula
CP0389217
(2R,3R,4S)-2-[(1R,2R)-3-acetamido-1,2-dihydroxypropyl]-3-(hexanoylamino)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
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C17H28N2O8
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0475517
(2R,3R,4S)-2-[(1R,2R)-3-acetamido-1,2-dihydroxypropyl]-4-hydroxy-3-(pentanoylamino)-3,4-dihydro-2H-pyran-6-carboxylic acid
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C16H26N2O8
 1
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0490887
(2R,3R,4S)-2-[(1R,2R)-1,2-dihydroxy-3-(propanoylamino)propyl]-3-(hexanoylamino)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
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C18H30N2O8
 1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
CP0455401
(2R,3R,4S)-3-(hexanoylamino)-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
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C15H25NO8
 2
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
2
Ki = 180 nM
   TI
   LI
   LO
   TS
CP0955517
5-(2-Methyl)hexanamido(S/R)-9-acetanamido-2,6-anhydro-3,5-dideoxy-D-glycero-D-galactonon-2-enonic acid
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C18H30N2O8
 1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CP0964588
5-(2-Methyl)hexanamido(S/R)-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic acid
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C16H27NO8
 1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0954501
5-(2-Ethyl)hexanamido(S/R)-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic acid
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C17H29NO8
 1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
CP0490888
(2R,3R,4S)-4-hydroxy-3-(pentanoylamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
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C14H23NO8
 2
1
IC50 = 990 nM
   TI
   LI
   LO
   TS
2
Ki = 240 nM
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   LO
   TS
CP0962534
5-Pentanamido-9-(4-biphenyl)-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic acid
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C26H31NO7
 1
1
IC50 = 990 nM
   TI
   LI
   LO
   TS
CP0394777
(2R,3R,4S)-2-[(1R,2R)-3-(butanoylamino)-1,2-dihydroxypropyl]-3-(hexanoylamino)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
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C19H32N2O8
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0478940
(2R,3R,4S)-2-[(1R,2R)-3-(hexanoylamino)-1,2-dihydroxypropyl]-4-hydroxy-3-(propanoylamino)-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C18H30N2O8
 1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0536335
(2R,3R,4S)-2-[(1R,2R)-1,2-dihydroxy-3-(pentanoylamino)propyl]-4-hydroxy-3-(pentanoylamino)-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C19H32N2O8
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0482392
(2R,3R,4S)-2-[(1R,2R)-1,2-dihydroxy-3-(pentanoylamino)propyl]-4-hydroxy-3-(propanoylamino)-3,4-dihydro-2H-pyran-6-carboxylic acid
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C17H28N2O8
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0534609
(2R,3R,4S)-4-hydroxy-3-(4-methylpentanoylamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
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C15H25NO8
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0956726
5-(2-Ethyl)hexanamido(S/R)-9-acetanamido-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic acid
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C19H32N2O8
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0536337
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-[(4-acetamidobenzoyl)amino]-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
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C20H25N3O9
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0482938
(2R,3R,4S)-3-(heptanoylamino)-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
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C16H27NO8
 1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
CP0290417
(2R,3R,4S)-3-acetamido-2-((1R,2R)-3-benzamido-1,2-dihydroxypropyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylate
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C18H22N2O8
 1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0567260
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-1,2-dihydroxy-3-(3-methylbutanoylamino)propyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C16H26N2O8
 1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0552045
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-(hexanoylamino)-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C17H28N2O8
 1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0546594
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-1,2-dihydroxy-3-(4-methylpentanoylamino)propyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C17H28N2O8
 1
1
IC50 = 3200 nM
   TI
   LI
   LO
   TS
CP0466365
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-1,2-dihydroxy-3-(pentanoylamino)propyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C16H26N2O8
 2
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
2
Ki = 830 nM
   TI
   LI
   LO
   TS
CP0546595
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-(butanoylamino)-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C15H24N2O8
 1
1
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0415064
(2R,3R,4S)-3-(hexanoylamino)-2-[(1R,2R)-3-(hexanoylamino)-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C21H36N2O8
 1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS
CP0478942
(2R,3R,4S)-4-hydroxy-3-(2-methylpropanoylamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C13H21NO8
 1
1
IC50 = 5300 nM
   TI
   LI
   LO
   TS
CP0393977
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-[(3-aminobenzoyl)amino]-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C18H23N3O8
 1
1
IC50 = 6500 nM
   TI
   LI
   LO
   TS
CP0415065
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-[(3-acetamidobenzoyl)amino]-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C20H25N3O9
 2
1
IC50 = 6500 nM
   TI
   LI
   LO
   TS
2
IC50 = 7500 nM
   TI
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   TS
CP0493554
(2R,3R,4S)-3-(cyclopropanecarbonylamino)-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
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C13H19NO8
 1
1
IC50 = 6900 nM
   TI
   LI
   LO
   TS
CP0538046
(2R,3R,4S)-3-(butanoylamino)-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C13H21NO8
 1
1
IC50 = 8400 nM
   TI
   LI
   LO
   TS
CP0387378
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-(heptanoylamino)-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C18H30N2O8
 1
1
IC50 = 9900 nM
   TI
   LI
   LO
   TS
CP0388435
(4S,5R,6R)-5-acetamido-6-((1S,2S)-1,2-dihydroxy-3-pentanamidopropyl)-4-hydroxy-5,6-dihydro-4H-pyran-2-carboxylic acid
   Show/Hide
C16H26N2O8
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0446403
(2R,3R,4S)-3-benzamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C16H19NO8
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0493553
(2R,3R,4S)-3-(cyclobutanecarbonylamino)-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C14H21NO8
 1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0445048
(4S,5R,6R)-5-acetamido-6-((1S,2S)-3-benzamido-1,2-dihydroxypropyl)-4-hydroxy-5,6-dihydro-4H-pyran-2-carboxylic acid
   Show/Hide
C18H22N2O8
 1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS
CP0475518
(2R,3R,4S)-4-(diaminomethylideneamino)-3-(4-methylpentanoylamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C16H28N4O7
 1
1
IC50 = 14000 nM
   TI
   LI
   LO
   TS
CP0405653
(2R,3R,4S)-4-hydroxy-3-(propanoylamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C12H19NO8
 1
1
IC50 = 18000 nM
   TI
   LI
   LO
   TS
CP0108317
(2R,3R,4S)-3-(2-azidoacetamido)-4-hydroxy-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylate
   Show/Hide
C11H16N4O8
 1
1
IC50 = 24000 nM
   TI
   LI
   LO
   TS
CP0909770
5-(N-2-azidoacetyl)-2,3,5-trideoxy-D-glycero-D-galacto-2-nonulopyranosonic acid
   Show/Hide
C10H14N4O8
 1
1
IC50 = 24000 nM
   TI
   LI
   LO
   TS
CP0451102
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-[(4-aminobenzoyl)amino]-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C18H23N3O8
 1
1
IC50 = 29000 nM
   TI
   LI
   LO
   TS
CP0467214
(4S,5R,6R)-5-acetamido-6-((1S,2S)-3-butyramido-1,2-dihydroxypropyl)-4-hydroxy-5,6-dihydro-4H-pyran-2-carboxylic acid
   Show/Hide
C15H24N2O8
 1
1
IC50 = 32000 nM
   TI
   LI
   LO
   TS
CP0393979
(2R,3R,4S)-4-hydroxy-3-(3-methylbutanoylamino)-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C14H23NO8
 1
1
IC50 = 32000 nM
   TI
   LI
   LO
   TS
CP0495663
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-1,2-dihydroxy-3-[4-(4-methoxyphenyl)triazol-1-yl]propyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C20H24N4O8
 1
1
IC50 = 47000 nM
   TI
   LI
   LO
   TS
CP0056939
(2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C11H17NO8
 2
1
IC50 = 49000 nM
   TI
   LI
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   TS
2
Ki = 12000 nM
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   TS
CP0482936
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-1,2-dihydroxy-3-[4-(4-methylphenyl)triazol-1-yl]propyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C20H24N4O7
 1
1
IC50 = 51000 nM
   TI
   LI
   LO
   TS
CP0467213
(4S,5R,6R)-5-acetamido-6-((1S,2S)-3-acetamido-1,2-dihydroxypropyl)-4-hydroxy-5,6-dihydro-4H-pyran-2-carboxylic acid
   Show/Hide
C13H20N2O8
 1
1
IC50 = 58000 nM
   TI
   LI
   LO
   TS
CP0566497
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-[4-(4-acetamidophenyl)triazol-1-yl]-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C21H25N5O8
 1
1
IC50 = 59000 nM
   TI
   LI
   LO
   TS
CP0482935
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-[4-(4-aminophenyl)triazol-1-yl]-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C19H23N5O7
 1
1
IC50 = 76000 nM
   TI
   LI
   LO
   TS
CP0405650
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-1,2-dihydroxy-3-(4-pentyltriazol-1-yl)propyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C18H28N4O7
 1
1
IC50 = 77000 nM
   TI
   LI
   LO
   TS
CP0482937
(2R,3R,4S)-3-acetamido-2-[(1R,2R)-3-[4-(4-fluorophenyl)triazol-1-yl]-1,2-dihydroxypropyl]-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C19H21FN4O7
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0415071
(2R,3R,4S)-3-[[2-[4-(4-aminophenyl)triazol-1-yl]acetyl]amino]-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
   Show/Hide
C19H23N5O8
 1
1
Ki = 53 nM
   TI
   LI
   LO
   TS