| Compound ID |
Compound Name |
Compound Formula |
|
CP0137017
|
6-[2-(4-fluorophenyl)ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C12H11FN2O2
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0265142
|
6-[2-[3-(trifluoromethyl)phenyl]ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C13H11F3N2O2
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0137019
|
6-[2-(4-chlorophenyl)ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C12H11ClN2O2
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0205967
|
6-[2-(3-fluorophenyl)ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C12H11FN2O2
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0121086
|
6-(1-phenylethyl)-1,2-dihydropyridazine-3,4-dione
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|
C12H12N2O2
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0186475
|
6-[2-(4-methoxyphenyl)ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C13H14N2O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0231655
|
6-(2-phenylethyl)-1,2-dihydropyridazine-3,4-dione
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|
C12H12N2O2
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0137018
|
6-[2-(2-fluorophenyl)ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C12H11FN2O2
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0184745
|
6-[2-[4-(trifluoromethyl)phenyl]ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C13H11F3N2O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0265140
|
6-[2-(3-methoxyphenyl)ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C13H14N2O3
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0174406
|
US10202399, Example 237
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|
C11H10N2O3
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0205973
|
US9212147, 40
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|
C12H18N2O2
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0367093
|
6-[2-(3,5-difluorophenyl)ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C12H10F2N2O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0231654
|
6-[2-(3,5-dimethoxyphenyl)ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C14H16N2O4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0129275
|
6-[2-[2-(trifluoromethyl)phenyl]ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C13H11F3N2O2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0717824
|
(E)-6-(4-chlorostyryl)-4-hydroxypyridazin-3(2H)-one
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|
C12H9ClN2O2
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0164978
|
6-(3-phenylpropyl)-1,2-dihydropyridazine-3,4-dione
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|
C13H14N2O2
|
1
|
| 1 |
IC50 = 1217 nM
|
|
|
|
CP0121087
|
6-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-1,2-dihydropyridazine-3,4-dione
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|
C14H10F6N2O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0164975
|
6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one
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|
C10H14N2O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0443179
|
6-(3,3-dimethylbutyl)-1,2-dihydropyridazine-3,4-dione
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|
C10H16N2O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
