Compound ID |
Compound Name |
Compound Formula |
CP0341603
|
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]pentanediamide
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|
C57H76N14O10
|
1
|
1 |
EC50 = 0.55 nM
|
|
|
CP0425447
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C38H47N5O2
|
2
|
1 |
EC50 = 603 nM
|
|
|
2 |
IC50 = 320 nM
|
|
|
CP0914282
|
10-butyl-11-(2-chloro-6-fluorophenyl)-3,3,8-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C26H30ClFN2O
|
1
|
1 |
IC50 = 150 nM
|
|
|
CP0914497
|
11-(2-chloro-6-fluorophenyl)-3,3,8,10-tetramethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C23H24ClFN2O
|
1
|
1 |
IC50 = 170 nM
|
|
|
CP0947408
|
11-(2-chloro-6-fluorophenyl)-10-ethyl-3,3,8-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C24H26ClFN2O
|
1
|
1 |
IC50 = 180 nM
|
|
|
CP0893234
|
3,3,8-trimethyl-11-(2-(methylthio)phenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C23H26N2OS
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0926231
|
11'-(2-chlorophenyl)-8'-methyl-4',5',10',11'-tetrahydrospiro[cyclopentane-1,3'-dibenzo[b,e][1,4]diazepin]-1'(2'H)-one
Show/Hide
|
C24H25ClN2O
|
1
|
1 |
IC50 = 240 nM
|
|
|
CP0916039
|
3,3,8-trimethyl-11-(2-(trifluoromethyl)phenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C23H23F3N2O
|
1
|
1 |
IC50 = 250 nM
|
|
|
CP0924707
|
8'-methyl-11'-(2-(methylthio)phenyl)-4',5',10',11'-tetrahydrospiro[cyclopentane-1,3'-dibenzo[b,e][1,4]diazepin]-1'(2'H)-one
Show/Hide
|
C25H28N2OS
|
1
|
1 |
IC50 = 250 nM
|
|
|
CP0916142
|
11-(2-chlorophenyl)-3,3,8-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H23ClN2O
|
1
|
1 |
IC50 = 280 nM
|
|
|
CP0947409
|
11'-(2-chloro-6-fluorophenyl)-8'-methyl-4',5',10',11'-tetrahydrospiro[cyclopentane-1,3'-dibenzo[b,e][1,4]diazepin]-1'(2'H)-one
Show/Hide
|
C24H24ClFN2O
|
1
|
1 |
IC50 = 280 nM
|
|
|
CP0750188
|
11-(2-chloro-6-fluorophenyl)-3,3,8-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H22ClFN2O
|
2
|
1 |
IC50 = 300 nM
|
|
|
2 |
IC50 = 5500 nM
|
|
|
CP0052175
|
(S)-2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-indol-3-yl)-2-methyl-N-(1-pyridin-2-yl-cyclohexylmethyl)-propionamide
Show/Hide
|
C37H47N5O2
|
1
|
1 |
IC50 = 350 nM
|
|
|
CP0914279
|
11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-8-(trifluoromethyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H19ClF4N2O
|
1
|
1 |
IC50 = 370 nM
|
|
|
CP0860622
|
11-(2-chloro-6-fluorophenyl)-3,8-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C21H20ClFN2O
|
1
|
1 |
IC50 = 450 nM
|
|
|
CP0916040
|
11'-(2-fluoro-6-(trifluoromethyl)phenyl)-8'-methyl-4',5',10',11'-tetrahydrospiro[cyclopentane-1,3'-dibenzo[b,e][1,4]diazepin]-1'(2'H)-one
Show/Hide
|
C25H24F4N2O
|
1
|
1 |
IC50 = 540 nM
|
|
|
CP0916085
|
3,3,8-trimethyl-11-(2-nitrophenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H23N3O3
|
1
|
1 |
IC50 = 550 nM
|
|
|
CP0860624
|
8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5',10',11'-tetrahydrospiro[cyclopentane-1,3'-dibenzo[b,e][1,4]diazepin]-1'(2'H)-one
Show/Hide
|
C25H25F3N2O
|
1
|
1 |
IC50 = 580 nM
|
|
|
CP0539557
|
3-[3-(2-Methyl-4-nitro-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C33H36N6O4
|
1
|
1 |
IC50 = 620 nM
|
|
|
CP0902956
|
8'-methyl-11'-(2-(trifluoromethylthio)phenyl)-4',5',10',11'-tetrahydrospiro[cyclopentane-1,3'-dibenzo[b,e][1,4]diazepin]-1'(2'H)-one
Show/Hide
|
C25H25F3N2OS
|
1
|
1 |
IC50 = 640 nM
|
|
|
CP0530253
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-methyl-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C39H49N5O2
|
1
|
1 |
IC50 = 660 nM
|
|
|
CP0531978
|
3-[3-(4-Nitro-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C32H34N6O4
|
1
|
1 |
IC50 = 800 nM
|
|
|
CP0947410
|
11-(2-chloro-6-fluorophenyl)-3-isopropyl-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C23H24ClFN2O
|
1
|
1 |
IC50 = 810 nM
|
|
|
CP0874223
|
8-chloro-11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C21H19Cl2FN2O
|
1
|
1 |
IC50 = 860 nM
|
|
|
CP0528941
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-4,7-difluoro-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C38H45F2N5O2
|
1
|
1 |
IC50 = 1010 nM
|
|
|
CP0903070
|
11-(2-methoxyphenyl)-3,3,8-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C23H26N2O2
|
1
|
1 |
IC50 = 1100 nM
|
|
|
CP0374706
|
3-[3-(4-Trifluoromethyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C33H34F3N5O2
|
1
|
1 |
IC50 = 1110 nM
|
|
|
CP0893235
|
11-(2-fluorophenyl)-3,3,8-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H23FN2O
|
1
|
1 |
IC50 = 1300 nM
|
|
|
CP0914280
|
11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-1-oxo-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepine-8-carbonitrile
Show/Hide
|
C22H19ClFN3O
|
1
|
1 |
IC50 = 1300 nM
|
|
|
CP0947407
|
11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-8-(trifluoromethoxy)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H19ClF4N2O2
|
1
|
1 |
IC50 = 1300 nM
|
|
|
CP0893236
|
11-(2-chloro-6-fluorophenyl)-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C20H18ClFN2O
|
1
|
1 |
IC50 = 1400 nM
|
|
|
CP0415566
|
5-(3-{3-[(1-Pyridin-2-yl-cyclohexylmethyl)-carbamoyl]-2,3,4,9-tetrahydro-1H-carbazol-3-yl}-ureido)-isophthalic acid diethyl ester
Show/Hide
|
C38H43N5O6
|
1
|
1 |
IC50 = 1850 nM
|
|
|
CP0481167
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-trifluoromethoxy-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C39H46F3N5O3
|
1
|
1 |
IC50 = 1890 nM
|
|
|
CP0914498
|
11-(2-chloro-6-fluorophenyl)-3-(4-methoxyphenyl)-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C27H24ClFN2O2
|
1
|
1 |
IC50 = 2000 nM
|
|
|
CP0522676
|
7-Bromo-3-[3-(2,6-diisopropyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C38H46BrN5O2
|
1
|
1 |
IC50 = 2140 nM
|
|
|
CP0860620
|
11-(2-chloro-6-fluorophenyl)-8-methoxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H22ClFN2O2
|
1
|
1 |
IC50 = 2200 nM
|
|
|
CP0376459
|
3-[3-(3-Acetyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C34H37N5O3
|
1
|
1 |
IC50 = 2270 nM
|
|
|
CP0914281
|
11-(2,6-difluorophenyl)-3,3,8-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H22F2N2O
|
1
|
1 |
IC50 = 2500 nM
|
|
|
CP0926230
|
11-(2-chloro-6-fluorophenyl)-3-(furan-2-yl)-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C24H20ClFN2O2
|
1
|
1 |
IC50 = 3000 nM
|
|
|
CP0448121
|
3-[3-(4-Trifluoromethoxy-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C33H34F3N5O3
|
1
|
1 |
IC50 = 3040 nM
|
|
|
CP0461250
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclopropylmethyl)-amide
Show/Hide
|
C35H41N5O2
|
1
|
1 |
IC50 = 3350 nM
|
|
|
CP0487543
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-trifluoromethyl-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C39H46F3N5O2
|
1
|
1 |
IC50 = 3660 nM
|
|
|
CP0380791
|
3-(3-Cyclohexyl-ureido)-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C32H41N5O2
|
1
|
1 |
IC50 = 3920 nM
|
|
|
CP0481190
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (2-methyl-2-pyridin-2-yl-propyl)-amide
Show/Hide
|
C35H43N5O2
|
1
|
1 |
IC50 = 4150 nM
|
|
|
CP0860623
|
11-(2-chloro-6-fluorophenyl)-3-(4-(dimethylamino)phenyl)-8-methyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C28H27ClFN3O
|
1
|
1 |
IC50 = 5400 nM
|
|
|
CP0532729
|
3-[3-(2,6-Dimethyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C34H39N5O2
|
1
|
1 |
IC50 = 5490 nM
|
|
|
CP0860621
|
3,3,8-trimethyl-11-phenyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C22H24N2O
|
1
|
1 |
IC50 = 6900 nM
|
|
|
CP0521888
|
3-[3-(2-Methoxy-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C33H37N5O3
|
1
|
1 |
IC50 = 8720 nM
|
|
|
CP0431072
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-nitro-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C38H46N6O4
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0481158
|
3-[3-(4-Nitro-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (2-pyridin-2-yl-ethyl)-amide
Show/Hide
|
C27H26N6O4
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0496531
|
3-(3-Ethyl-ureido)-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C28H35N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0505939
|
6-[3-(2,6-Diisopropyl-phenyl)-ureido]-6-[(1-pyridin-2-yl-cyclohexylmethyl)-carbamoyl]-6,7,8,9-tetrahydro-5H-carbazole-4-carboxylic acid
Show/Hide
|
C39H47N5O4
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0518238
|
3-[3-(4-Nitro-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1,1-dioxo-4-pyridin-2-yl-hexahydro-1lambda*6*-thiopyran-4-ylmethyl)-amide
Show/Hide
|
C31H32N6O6S
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0520189
|
3-[3-(4-Nitro-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (2-methyl-2-pyridin-2-yl-propyl)-amide
Show/Hide
|
C29H30N6O4
|
1
|
1 |
IC50 = 10000 nM
|
|
|
CP0521889
|
3-Ureido-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Show/Hide
|
C26H31N5O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0554951
|
3-[3-(2,6-Diisopropyl-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid [1-(4-chloro-phenyl)-cyclopropylmethyl]-amide
Show/Hide
|
C36H41ClN4O2
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0457508
|
11-(2-chloro-6-fluorophenyl)-3,3,5,8-tetramethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C23H24ClFN2O
|
1
|
1 |
IC50 = 10000 nM
|
|
|
CP0857638
|
11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-1-oxo-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepine-8-carboxylic acid
Show/Hide
|
C22H20ClFN2O3
|
1
|
1 |
IC50 = 10000 nM
|
|
|
CP0879859
|
11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-1-oxo-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepine-8-carboxamide
Show/Hide
|
C22H21ClFN3O2
|
1
|
1 |
IC50 = 10000 nM
|
|
|
CP0920425
|
10-(2-chloro-6-fluorophenyl)-7-methyl-2,3,9,10-tetrahydrobenzo[b]cyclopenta[e][1,4]diazepin-1(4H)-one
Show/Hide
|
C19H16ClFN2O
|
1
|
1 |
IC50 = 10000 nM
|
|
|
CP0921728
|
11-(2-chloro-6-fluorophenyl)-8-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
Show/Hide
|
C21H20ClFN2O2
|
1
|
1 |
IC50 = 10000 nM
|
|
|