Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02815 , Eukaryotic translation initiation factor 2-alpha kinase 3
 Protein Info 
Gene Name EIF2AK3
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q9NZJ5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT02815
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0247164
 Compound Info 
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-fluoro-2,3-dihydroindol-1-yl]-2-(2-methyl-1H-indol-3-yl)ethanone
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C29H26FN5O3
  1
1
IC50 = 12.59 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0537557
 Compound Info 
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]-2-(2-methyl-1H-indol-3-yl)ethanone
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C29H27N5O3
  1
1
IC50 = 19.95 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0474367
 Compound Info 
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]-2-(6-fluoro-2-methyl-1H-indol-3-yl)ethanone
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C29H26FN5O3
  1
1
IC50 = 25.12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0508306
 Compound Info 
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]-2-(7-fluoro-2-methyl-1H-indol-3-yl)ethanone
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C29H26FN5O3
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555049
 Compound Info 
2-(2,5-difluorophenyl)-1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]ethanone
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C26H22F2N4O3
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555752
 Compound Info 
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]-2-(6-fluoro-2-methylindol-1-yl)ethanone
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C29H26FN5O3
  1
1
IC50 = 79.43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0553571
 Compound Info 
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]-2-indol-1-ylethanone
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C28H25N5O3
  1
1
IC50 = 316.23 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0303258
 Compound Info 
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]-2-(1H-indol-3-yl)ethanone
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C28H25N5O3
  1
1
IC50 = 501.19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0426670
 Compound Info 
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]-2-(1-methylpyrazol-3-yl)ethanone
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C24H24N6O3
  1
1
IC50 = 7943.28 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0174802
 Compound Info 
2-(1-benzofuran-3-yl)-1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]ethanone
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C28H24N4O4
  1
1
IC50 > 31622.78 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS