Brief Information of the Compound and Protein
Compound Name
1-[5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,3-dihydroindol-1-yl]-2-(6-fluoro-2-methylindol-1-yl)ethanone
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PubChem ID
CID: 86281960
Canonical SMILES
COc1cc2ncnc(Nc3ccc4N(CCc4c3)C(=O)Cn3c(C)cc4ccc(F)cc34)c2cc1OC
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Compound Formula C29H26FN5O3
Compound Structure
Protein Name
Eukaryotic translation initiation factor 2-alpha kinase 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase PEK family
>
Other protein kinase PEK subfamily
Uniprot ID
Q9NZJ5
Gene Name
EIF2AK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 79.43 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.162 nM