Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02772 , C5a anaphylatoxin chemotactic receptor 1
Gene Name C5AR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P21730
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT02772
 
Compound ID Compound Name Compound Formula
CP0401881
N-[2-(cyclopentylamino)-1-(2-fluorophenyl)-2-oxoethyl]-N-(2,4-dimethoxyphenyl)benzamide
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C28H29FN2O4
 5
1
EC50 = 123.03 nM
   TI
   LI
   LO
   TS
2
IC50 = 25.12 nM
   TI
   LI
   LO
   TS
3
IC50 = 31.62 nM
   TI
   LI
   LO
   TS
4
IC50 = 39.81 nM
   TI
   LI
   LO
   TS
5
IC50 = 794.33 nM
   TI
   LI
   LO
   TS
CP0541916
N-(2,4-dimethoxyphenyl)-N-[1-(2-fluorophenyl)-2-[[(2R)-2-hydroxypropyl]amino]-2-oxoethyl]-3-methylfuran-2-carboxamide
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C25H27FN2O6
 1
1
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
CP0548963
N-(2,4-dimethoxyphenyl)-N-[1-(2-fluorophenyl)-2-[[(2R)-2-hydroxypropyl]amino]-2-oxoethyl]-2-methylfuran-3-carboxamide
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C25H27FN2O6
 1
1
IC50 = 39.81 nM
   TI
   LI
   LO
   TS
CP0371934
N-(2,4-dimethoxyphenyl)-N-[1-(2-fluorophenyl)-2-[[(2R)-2-hydroxypropyl]amino]-2-oxoethyl]benzamide
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C26H27FN2O5
 1
1
IC50 = 63.1 nM
   TI
   LI
   LO
   TS
CP0401880
N-[2-(cyclopentylamino)-1-(2-fluorophenyl)-2-oxoethyl]-N-(2,4-dimethoxyphenyl)furan-2-carboxamide
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C26H27FN2O5
 4
1
IC50 = 79.43 nM
   TI
   LI
   LO
   TS
2
IC50 = 125.89 nM
   TI
   LI
   LO
   TS
3
IC50 = 251.19 nM
   TI
   LI
   LO
   TS
4
IC50 = 3162.28 nM
   TI
   LI
   LO
   TS
CP0503481
N-(2,4-dimethoxyphenyl)-N-[1-(2-fluorophenyl)-2-[[(2R)-2-hydroxypropyl]amino]-2-oxoethyl]-3-(methoxymethyl)furan-2-carboxamide
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C26H29FN2O7
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0045051
(S)-N-((3R,6S,9S,15S,20aS)-6-((1H-indol-3-yl)methyl)-3-(cyclohexylmethyl)-9-(3-guanidinopropyl)-1,4,7,10,16-pentaoxoicosahydropyrrolo[1,2-a][1,4,7,10,13]pentaazacyclooctadecin-15-yl)-2-acetamido-3-phenylpropanamide
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C47H65N11O7
 1
1
IC50 = 104 nM
   TI
   LI
   LO
   TS
CP0668763
Hoo-Phe-Orn-Pro-hle-Pff-Phe-NH2
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C49H63FN10O9
 1
1
IC50 = 111 nM
   TI
   LI
   LO
   TS
CP0423233
3-chloro-N-(2,4-dimethoxyphenyl)-N-[1-(2-fluorophenyl)-2-[[(2R)-2-hydroxypropyl]amino]-2-oxoethyl]furan-2-carboxamide
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C24H24ClFN2O6
 1
1
IC50 = 199.53 nM
   TI
   LI
   LO
   TS
CP0439811
2-chloro-N-(2,4-dimethoxyphenyl)-N-[1-(2-fluorophenyl)-2-[[(2R)-2-hydroxypropyl]amino]-2-oxoethyl]furan-3-carboxamide
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C24H24ClFN2O6
 1
1
IC50 = 316.23 nM
   TI
   LI
   LO
   TS
CP0427112
2-(N-acetyl-2,4-dimethoxyanilino)-N-cyclopentyl-2-(2-fluorophenyl)acetamide
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C23H27FN2O4
 1
1
IC50 = 794.33 nM
   TI
   LI
   LO
   TS
CP0439810
N-(2,4-dimethoxyphenyl)-N-[2-[1-(dimethylamino)propan-2-ylamino]-1-(2-fluorophenyl)-2-oxoethyl]benzamide
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C28H32FN3O4
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0423231
N-(2,4-dimethoxyphenyl)-3-[(dimethylamino)methyl]-N-[1-(2-fluorophenyl)-2-[[(2R)-2-hydroxypropyl]amino]-2-oxoethyl]furan-2-carboxamide
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C27H32FN3O6
 1
1
IC50 = 3162.28 nM
   TI
   LI
   LO
   TS
CP0419114
N-[1-(cyclopentylamino)-1-oxopropan-2-yl]-N-(2,4-dimethoxyphenyl)benzamide
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C23H28N2O4
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0423237
N-[2-(cyclopentylamino)-1-(2-fluorophenyl)-2-oxoethyl]-N-methylbenzamide
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C21H23FN2O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0423238
2-(N-benzoyl-2,4-dimethoxyanilino)-2-(2-fluorophenyl)acetic acid
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C23H20FNO5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0506599
N-(2,4-dimethoxyphenyl)-N-[1-(2-fluorophenyl)-2-[[(2S)-2-hydroxypropyl]amino]-2-oxoethyl]benzamide
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C26H27FN2O5
 1
1
IC50 > 100 nM
   TI
   LI
   LO
   TS