Brief Information of the Compound and Protein
Compound Name
N-[2-(cyclopentylamino)-1-(2-fluorophenyl)-2-oxoethyl]-N-(2,4-dimethoxyphenyl)benzamide
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PubChem ID
CID: 44590341
Canonical SMILES
COc1ccc(N(C(C(=O)NC2CCCC2)c2ccccc2F)C(=O)c2ccccc2)c(OC)c1
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Compound Formula C28H29FN2O4
Compound Structure
Protein Name
C5a anaphylatoxin chemotactic receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Anaphylatoxin receptor family
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Anaphylatoxin receptor
Uniprot ID
P21730
Gene Name
C5AR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  5
1
EC50 = 123.03 nM
   TI
   LI
   LO
   TS
2
IC50 = 25.12 nM
   TI
   LI
   LO
   TS
3
IC50 = 31.62 nM
   TI
   LI
   LO
   TS
4
IC50 = 39.81 nM
   TI
   LI
   LO
   TS
5
IC50 = 794.33 nM
   TI
   LI
   LO
   TS