| Compound ID |
Compound Name |
Compound Formula |
|
CP0402742
|
(2S,4S)-N-[(2S)-1-fluoro-3,3-dimethylbutan-2-yl]-9-(4-oxidopyrazin-4-ium-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H22FN5O2
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0463801
|
(2S,4S)-9-(4-oxidopyrazin-4-ium-2-yl)-N-[1-(trifluoromethyl)cyclobutyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C17H16F3N5O2
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0473684
|
(2S,4S)-9-(4-oxidopyrazin-4-ium-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C16H16F3N5O2
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0403234
|
(2S,4S)-N-[(2S)-1-fluoro-3-methylbutan-2-yl]-9-(4-oxidopyrazin-4-ium-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C17H20FN5O2
|
1
|
| 1 |
EC50 = 6.4 nM
|
|
|
|
CP0459091
|
(2S,4S)-N-[1-(hydroxymethyl)cyclopentyl]-9-(4-oxidopyrazin-4-ium-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H21N5O3
|
1
|
| 1 |
EC50 = 6.8 nM
|
|
|
|
CP0204257
|
APD-371
Show/Hide
|
C18H23N5O3
|
1
|
| 1 |
EC50 = 7.6 nM
|
|
|
|
CP0473682
|
(2S,4S)-9-(4-oxidopyrazin-4-ium-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C16H14F3N5O2
|
1
|
| 1 |
EC50 = 14.5 nM
|
|
|
|
CP0416863
|
(2R,4R)-N-[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]-9-pyrazin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H23N5O2
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0482613
|
(2S,4S)-9-(4-oxidopyrazin-4-ium-2-yl)-N-[(2S)-1,1,1-trifluoro-3-hydroxypropan-2-yl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C15H14F3N5O3
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0477572
|
(2S,4S)-N-[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]-9-pyrazin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H23N5O2
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
|
CP0475675
|
(2S,4S)-N-[(2S)-1-hydroxy-3-methylbutan-2-yl]-9-(4-oxidopyrazin-4-ium-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C17H21N5O3
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0412791
|
(2S,4S)-N-[(1S)-2-hydroxy-1-phenylethyl]-9-(4-oxidopyrazin-4-ium-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C20H19N5O3
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0155571
|
(2R,4R)-9-(2,4-difluorophenyl)-N-(1-hydroxy-2-methylpropan-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C18H19F2N3O2
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0402740
|
(2S,4S)-N-(1-methylcyclopropyl)-9-(4-oxidopyrazin-4-ium-2-yl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C16H17N5O2
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0487953
|
(2R,4R)-N-(1-hydroxy-2-methylpropan-2-yl)-9-pyrazin-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C16H19N5O2
|
1
|
| 1 |
EC50 = 320 nM
|
|
|
|
CP0416864
|
(2S,4S)-9-(4-oxidopyrazin-4-ium-2-yl)-N-[(2R)-1,1,1-trifluoro-3-hydroxypropan-2-yl]-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C15H14F3N5O3
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0400698
|
N-propyl-2-(tricyclo[3.3.1.03,7]nonane-3-carbonylamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
Show/Hide
|
C21H28N2O3S
|
3
|
| 1 |
IC50 = 9.333 nM
|
|
|
| 2 |
IC50 = 1548.82 nM
|
|
|
| 3 |
Ki = 33.88 nM
|
|
|
|
CP0400705
|
N-[3-(3,3-difluoroazetidine-1-carbonyl)-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl]tricyclo[3.3.1.03,7]nonane-3-carboxamide
Show/Hide
|
C21H24F2N2O3S
|
2
|
| 1 |
IC50 = 9.55 nM
|
|
|
| 2 |
Ki = 46.77 nM
|
|
|
|
CP0410344
|
N-propyl-2-[(2,2,3,3-tetramethylcyclopropanecarbonyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
Show/Hide
|
C19H28N2O3S
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 4.365 nM
|
|
|
|
CP0410345
|
2-(adamantane-1-carbonylamino)-N-propyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
Show/Hide
|
C22H30N2O3S
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
|
CP0411351
|
US8895592, 19
Show/Hide
|
C21H27F3N2O3S
|
1
|
| 1 |
Ki = 0.15 nM
|
|
|
|
CP0402796
|
US8846730, 40
Show/Hide
|
C25H33F3N4O4S
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0543942
|
US8846730, 72
Show/Hide
|
C26H33F3N2O4S
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0573332
|
US8846730, 23
Show/Hide
|
C25H31F3N2O4S
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0545677
|
US8859596, 164
Show/Hide
|
C22H28F6N4O2S
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0417828
|
US8846730, 81
Show/Hide
|
C23H29F3N2O4S
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0460005
|
US8846730, 73
Show/Hide
|
C23H28F3N3O4S
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0488979
|
US8846730, 79
Show/Hide
|
C23H30F3N3O3S
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0519862
|
US8846730, 22
Show/Hide
|
C25H31F3N2O4S
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0538617
|
US8846730, 50
Show/Hide
|
C25H33F3N2O4S
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0463805
|
US8859596, 193
Show/Hide
|
C23H32F3N5O2S
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
|
CP0375379
|
US8846730, 4
Show/Hide
|
C26H34F3N3O3S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0468403
|
US8859596, 169
Show/Hide
|
C23H31F3N4O3S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0545676
|
US8859596, 162
Show/Hide
|
C21H31ClN4O2S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0390100
|
US8859596, 197
Show/Hide
|
C24H27F3N6O2S
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0390265
|
US8859596, 192
Show/Hide
|
C20H26F3N5O3S
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0450107
|
US8859596, 147
Show/Hide
|
C24H33F3N4O3S
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0486536
|
US8895592, 30
Show/Hide
|
C23H28F3N3O2S
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0460111
|
US8895592, 37
Show/Hide
|
C25H28F3N5O2S
|
1
|
| 1 |
Ki = 0.77 nM
|
|
|
|
CP0506904
|
US8859596, 144
Show/Hide
|
C21H29F3N4O2S
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0535624
|
US8859596, 165
Show/Hide
|
C23H31F3N4O2S
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0407090
|
US8846730, 51
Show/Hide
|
C26H34F3N3O2S2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0415067
|
US8846730, 69
Show/Hide
|
C17H16Cl2N2O3
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0410558
|
US8859596, 191
Show/Hide
|
C24H27F3N6O2S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0426609
|
US8859596, 188
Show/Hide
|
C22H28F3N5O2S
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0409765
|
US8895592, 23
Show/Hide
|
C23H32F3N3O2S
|
1
|
| 1 |
Ki = 0.95 nM
|
|
|
|
CP0469773
|
US8859596, 154
Show/Hide
|
C20H25F3N4O3S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0409849
|
US8895592, 2
Show/Hide
|
C20H26ClN3O3S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0415721
|
US8895592, 15
Show/Hide
|
C21H27ClN2O2S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0472489
|
US8895592, 17
Show/Hide
|
C22H24F3N3O2S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0535625
|
US8859596, 174
Show/Hide
|
C22H30F4N4O2S
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0385257
|
US8895592, 32
Show/Hide
|
C23H31F3N2O3S
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0458967
|
US8846730, 83
Show/Hide
|
C25H30F3N3O3S
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0390101
|
US8859596, 151
Show/Hide
|
C22H28F3N5O2S
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0545678
|
US8859596, 200
Show/Hide
|
C26H31F3N6O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0397839
|
US8895592, 18
Show/Hide
|
C23H29F3N2O4S
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0429708
|
US8846730, 5
Show/Hide
|
C27H36F3N3O3S
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0429189
|
US8846730, 54
Show/Hide
|
C26H33F4N3O3S
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0429661
|
US8895592, 31
Show/Hide
|
C23H28F3N3O2S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0420626
|
US8846730, 39
Show/Hide
|
C24H33F3N4O2S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0491211
|
US8846730, 82
Show/Hide
|
C29H40F3N3O4S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0390095
|
US8859596, 176
Show/Hide
|
C22H28F3N5O4S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0390096
|
US8859596, 181
Show/Hide
|
C23H32F3N5O3S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0545674
|
US8859596, 198
Show/Hide
|
C25H36F3N5O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0464057
|
US8859596, 34
Show/Hide
|
C22H31F3N4O2S
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0401178
|
US8846730, 44
Show/Hide
|
C25H32F3N3O3S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0460191
|
US8895592, 36
Show/Hide
|
C21H22F3N3O3S
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0506907
|
US8859596, 199
Show/Hide
|
C26H31F3N6O2
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0509469
|
US8895592, 38
Show/Hide
|
C25H28F3N5O2S
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0535627
|
US8859596, 141
Show/Hide
|
C23H31F3N4O4S
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0440547
|
US8895592, 8
Show/Hide
|
C24H31F3N2O3S
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0488981
|
US8846730, 84
Show/Hide
|
C24H28F3N3O4S
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0422475
|
US8895592, 29
Show/Hide
|
C21H22F3N3O3S
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0524250
|
US8846730, 38
Show/Hide
|
C24H26F3N3O3S2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0542114
|
US8846730, 75
Show/Hide
|
C22H26F3N3O4S
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0546709
|
US8859596, 145
Show/Hide
|
C22H29F3N4O2S
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0488394
|
US8859596, 186
Show/Hide
|
C21H28F3N5O2S
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0381716
|
US8846730, 33
Show/Hide
|
C23H30F3N3O4S
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0420476
|
US8846730, 36
Show/Hide
|
C27H29F3N2O3S
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0443118
|
US8859596, 175
Show/Hide
|
C22H30F3N5O2S
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0462701
|
US8846730, 2
Show/Hide
|
C24H30F3N3O3S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0484505
|
US8846730, 48
Show/Hide
|
C26H34F3N3O5S2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0443116
|
US8859596, 163
Show/Hide
|
C22H29F3N4O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0390263
|
US8859596, 190
Show/Hide
|
C23H29F3N4O2S
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0563975
|
US8859596, 153
Show/Hide
|
C23H31F3N4O3S
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0408244
|
US8846730, 43
Show/Hide
|
C26H32F3N3O4S
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0385075
|
US8846730, 24
Show/Hide
|
C26H34F3N3O3S
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0400699
|
N-propyl-2-(tricyclo[3.3.1.03,7]nonane-3-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
Show/Hide
|
C22H30N2O2S
|
1
|
| 1 |
Ki = 3.548 nM
|
|
|
|
CP0414010
|
US8895592, 25
Show/Hide
|
C22H23F3N4O3S
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0422532
|
US8846730, 53
Show/Hide
|
C26H33F4N3O3S
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0390258
|
US8859596, 158
Show/Hide
|
C21H29F3N4O3S
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0464066
|
US8859596, 185
Show/Hide
|
C20H26F3N5O2S
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0408164
|
US8846730, 71
Show/Hide
|
C26H34F3N3O4S
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0390099
|
US8859596, 196
Show/Hide
|
C24H27F3N6O2S
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0546228
|
US8846730, 3
Show/Hide
|
C25H32F3N3O3S
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0429838
|
US8846730, 78
Show/Hide
|
C24H32F3N3O3S
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0409771
|
US8846730, 80
Show/Hide
|
C23H25F6N3O3S
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0461549
|
US8859596, 171
Show/Hide
|
C20H27F3N4O2S
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0464067
|
US8859596, 189
Show/Hide
|
C24H32F3N5O2S
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0420203
|
US8846730, 19
Show/Hide
|
C25H27F3N4O3S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0389373
|
US8846730, 56
Show/Hide
|
C24H27F3N4O3S
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0491022
|
US8846730, 66
Show/Hide
|
C25H32F3N3O4S
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0440503
|
US8895592, 4
Show/Hide
|
C22H29ClN2O3S
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0544120
|
US8895592, 16
Show/Hide
|
C23H29N3O2S
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0390261
|
US8859596, 167
Show/Hide
|
C21H27F3N4O2S
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0450108
|
US8859596, 201
Show/Hide
|
C19H25F3N6O2S
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0546808
|
US8859596, 159
Show/Hide
|
C23H33F3N4O2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0470283
|
US8859596, 149
Show/Hide
|
C24H35F3N4O2
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0503959
|
US8859596, 183
Show/Hide
|
C23H27F3N6OS
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0489612
|
6-methyl-N-propyl-2-(tricyclo[3.3.1.03,7]nonane-3-carbonylamino)-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide
Show/Hide
|
C22H31N3O2S
|
1
|
| 1 |
Ki = 5.888 nM
|
|
|
|
CP0952457
|
US8859596, 160
Show/Hide
|
C25H34F3N3O2
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0395560
|
N-[5-tert-butyl-3-[[(2R)-oxolan-2-yl]methyl]-1,3-thiazol-2-ylidene]-2-(pyridin-2-ylmethoxy)-5-(trifluoromethyl)benzamide
Show/Hide
|
C26H28F3N3O3S
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0443117
|
US8859596, 170
Show/Hide
|
C22H31F3N4O2S
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0470366
|
US8846730, 35
Show/Hide
|
C29H34F3N3O3S
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0380935
|
US8846730, 74
Show/Hide
|
C28H34F3N3O3S
|
1
|
| 1 |
Ki = 6.6 nM
|
|
|
|
CP0524245
|
US8846730, 63
Show/Hide
|
C29H38F3N3O5S
|
1
|
| 1 |
Ki = 6.6 nM
|
|
|
|
CP0563296
|
US8859596, 182
Show/Hide
|
C25H27F4N5O2S
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0426608
|
US8859596, 177
Show/Hide
|
C22H29F3N4O3S
|
1
|
| 1 |
Ki = 7.3 nM
|
|
|
|
CP0415632
|
US8895592, 26
Show/Hide
|
C23H24F3N3O3S
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0411384
|
US8895592, 9
Show/Hide
|
C25H34F3N3O2S
|
1
|
| 1 |
Ki = 7.7 nM
|
|
|
|
CP0389343
|
US8846730, 70
Show/Hide
|
C26H34F3N3O4S
|
1
|
| 1 |
Ki = 8.1 nM
|
|
|
|
CP0472511
|
US8846730, 55
Show/Hide
|
C26H35F3N4O2S
|
1
|
| 1 |
Ki = 8.1 nM
|
|
|
|
CP0429839
|
US8846730, 45
Show/Hide
|
C27H36F3N3O3S
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0558190
|
US8895592, 3
Show/Hide
|
C24H27F3N2O3S
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0472013
|
US8846730, 37
Show/Hide
|
C24H26F3N3O4S
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0458984
|
US8895592, 21
Show/Hide
|
C22H24F3N3O3S
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0472379
|
US8846730, 59
Show/Hide
|
C26H34N4O3S
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0464058
|
US8859596, 142
Show/Hide
|
C25H35F3N4O3
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0912378
|
US8859596, 157
Show/Hide
|
C25H34F3N3O2
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0395024
|
US8895592, 27
Show/Hide
|
C22H21F6N3O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0435108
|
US8846730, 21
Show/Hide
|
C26H28F3N3O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0456794
|
US8846730, 58
Show/Hide
|
C24H32F3N3O4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0464092
|
US8859596, 156
Show/Hide
|
C23H30F6N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0390260
|
US8859596, 161
Show/Hide
|
C25H35N5O3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0470289
|
US8859596, 180
Show/Hide
|
C22H27F3N4O3S
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0413979
|
US8895592, 7
Show/Hide
|
C25H34F3N3O2S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0543959
|
US8846730, 49
Show/Hide
|
C26H34F3N3O4S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0462788
|
US8895592, 14
Show/Hide
|
C23H30F3N3O2S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0425094
|
US8846730, 67
Show/Hide
|
C25H29F3N4O3S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0532691
|
US8846730, 34
Show/Hide
|
C27H37F3N4O3S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0535626
|
US8859596, 204
Show/Hide
|
C24H27F3N6O2S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0407676
|
US8846730, 6
Show/Hide
|
C26H34F3N3O3S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0548850
|
US8846730, 41
Show/Hide
|
C23H25F3N4O3S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0545675
|
US8859596, 146
Show/Hide
|
C24H33F3N4O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0555631
|
US8859596, 155
Show/Hide
|
C25H35F3N4O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0375414
|
US8846730, 1
Show/Hide
|
C24H30F3N3O3S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0415804
|
US8846730, 17
Show/Hide
|
C25H29F3N4O3S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0472442
|
US8846730, 57
Show/Hide
|
C26H34F3N3O3S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0468042
|
US8859596, 148
Show/Hide
|
C22H30F3N5OS
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0425026
|
US8846730, 8
Show/Hide
|
C25H32F3N3O3S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0546310
|
US8895592, 5
Show/Hide
|
C25H34F3N3O2S
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0531130
|
US8895592, 1
Show/Hide
|
C24H34BrN3O2S
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0462688
|
US8846730, 7
Show/Hide
|
C27H36F3N3O3S
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0461548
|
US8859596, 35
Show/Hide
|
C25H29F3N6OS
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0407061
|
US8846730, 46
Show/Hide
|
C28H38F3N3O3S
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0410579
|
US8859596, 168
Show/Hide
|
C24H35ClN4O3
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0382525
|
US8846730, 47
Show/Hide
|
C27H34F3N3O4S
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0415560
|
US8895592, 12
Show/Hide
|
C24H32F3N3O2S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0546218
|
US8895592, 35
Show/Hide
|
C22H24F3N3O3S
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0473480
|
US8846730, 12
Show/Hide
|
C25H32F3N3O3S
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0425346
|
US8846730, 30
Show/Hide
|
C26H34F3N3O3S
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0462638
|
US8859596, 152
Show/Hide
|
C22H31F3N4O2S
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0415899
|
US8895592, 11
Show/Hide
|
C26H34F3N3O3S
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0466663
|
US8859596, 203
Show/Hide
|
C24H27F3N6O2S
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0385228
|
US8895592, 24
Show/Hide
|
C23H28F3N3O2S
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0411899
|
US8895592, 33
Show/Hide
|
C24H27F3N4O2S
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0555377
|
US8859596, 184
Show/Hide
|
C25H36F3N5O3S
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0390267
|
US8859596, 202
Show/Hide
|
C25H30F3N5OS
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0538165
|
US8895592, 6
Show/Hide
|
C24H29F3N4O2S
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0424188
|
US8859596, 178
Show/Hide
|
C24H28F6N4O3
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0468404
|
US8859596, 194
Show/Hide
|
C23H28F6N4O2
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0506906
|
US8859596, 166
Show/Hide
|
C23H32F3N5O2S
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0571106
|
US8859596, 205
Show/Hide
|
C30H37F3N6O3S
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0385692
|
US8895592, 34
Show/Hide
|
C24H32F3N3O3S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0462717
|
US8895592, 20
Show/Hide
|
C23H26F3N3O3S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0442880
|
US8846730, 20
Show/Hide
|
C26H28F3N3O4S
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0472586
|
US8859596, 172
Show/Hide
|
C21H24F6N4O2S
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0389367
|
US8895592, 28
Show/Hide
|
C21H22F3N3O3S
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0512551
|
US8846730, 77
Show/Hide
|
C28H37F3N4O4S
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0474347
|
US8846730, 26
Show/Hide
|
C26H34F3N3O3S
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0396421
|
US8895592, 22
Show/Hide
|
C22H25F3N4O2S
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0429629
|
US8895592, 13
Show/Hide
|
C24H32F3N3O2S
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0472488
|
US8846730, 15
Show/Hide
|
C27H36F3N3O3S
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0431465
|
US8846730, 31
Show/Hide
|
C26H34F3N3O3S
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0480943
|
US8859596, 187
Show/Hide
|
C21H28F3N5OS
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0468190
|
US8895592, 10
Show/Hide
|
C24H35N3O2S
|
1
|
| 1 |
Ki = 243 nM
|
|
|
|
CP0410347
|
N-(2-methoxyethyl)-2-(tricyclo[3.3.1.03,7]nonane-3-carbonylamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
Show/Hide
|
C21H28N2O4S
|
1
|
| 1 |
Ki = 263.03 nM
|
|
|
|
CP0453065
|
2-(bicyclo[2.2.1]heptane-2-carbonylamino)-N-propyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
Show/Hide
|
C19H26N2O3S
|
1
|
| 1 |
Ki = 269.15 nM
|
|
|
|
CP0506905
|
US8859596, 150
Show/Hide
|
C24H33F3N4O2S
|
1
|
| 1 |
Ki = 283 nM
|
|
|
|
CP0443119
|
US8859596, 179
Show/Hide
|
C23H26F6N4O2
|
1
|
| 1 |
Ki = 288 nM
|
|
|
|
CP0400702
|
N-ethyl-2-(tricyclo[3.3.1.03,7]nonane-3-carbonylamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
Show/Hide
|
C20H26N2O3S
|
1
|
| 1 |
Ki = 295.12 nM
|
|
|
|
CP0410346
|
2-[[2-fluoro-6-(trifluoromethyl)benzoyl]amino]-N-propyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
Show/Hide
|
C19H18F4N2O3S
|
1
|
| 1 |
Ki = 331.13 nM
|
|
|
|
CP0400703
|
2-(2-oxatricyclo[3.3.1.13,7]decane-1-carbonylamino)-N-propyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
Show/Hide
|
C21H28N2O4S
|
1
|
| 1 |
Ki = 489.78 nM
|
|
|
|
CP0434911
|
N-[3-(morpholine-4-carbonyl)-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl]tricyclo[3.3.1.03,7]nonane-3-carboxamide
Show/Hide
|
C22H28N2O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
