Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT02131 , Adenosine receptor A2b
Gene Name ADORA2B
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P29276
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT02131
 
Compound ID Compound Name Compound Formula
CP0069838
(4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl ester
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C26H26N6O4
 1
1
Ki = 12.8 nM
   TI
   LI
   LO
   TS
CP0259712
N-[4-(3,5-dimethylphenyl)-5-pyridin-4-yl-1,3-thiazol-2-yl]pyridine-3-carboxamide
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C22H18N4OS
 1
1
Ki = 163 nM
   TI
   LI
   LO
   TS
CP0200052
1-Allyl-3-methyl-8-phenyl-3,7-dihydro-purine-2,6-dione
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C15H14N4O2
 1
1
Ki = 174 nM
   TI
   LI
   LO
   TS
CP0058033
1,3-dipropyl-8-cyclopentylxanthine
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C16H24N4O2
 1
1
Ki = 186 nM
   TI
   LI
   LO
   TS
CP0300612
1-Allyl-7-(2-chloro-ethyl)-3-methyl-8-phenyl-3,7-dihydro-purine-2,6-dione
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C17H17ClN4O2
 1
1
Ki = 1700 nM
   TI
   LI
   LO
   TS
CP0303870
1-Propyl-3,7-dihydro-purine-2,6-dione
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C8H10N4O2
 1
1
Ki = 1880 nM
   TI
   LI
   LO
   TS
CP0290021
3-Methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione
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C9H8N4O2
 1
1
Ki = 2150 nM
   TI
   LI
   LO
   TS
CP0367729
7-(2-Chloro-ethyl)-8-phenyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
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C19H23ClN4O2
 1
1
Ki = 3360 nM
   TI
   LI
   LO
   TS
CP0405406
7-(2-Chloro-ethyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
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C9H11ClN4O2
 1
1
Ki = 5390 nM
   TI
   LI
   LO
   TS
CP0300560
3-Methyl-1-phenethyl-3,7-dihydro-purine-2,6-dione
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C14H14N4O2
 1
1
Ki = 5530 nM
   TI
   LI
   LO
   TS
CP0094874
1-Benzyl-3-methyl-3,7-dihydro-purine-2,6-dione
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C13H12N4O2
 1
1
Ki = 10200 nM
   TI
   LI
   LO
   TS
CP0404084
7-(3-Chloro-propyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
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C10H13ClN4O2
 1
1
Ki = 14200 nM
   TI
   LI
   LO
   TS
CP0042654
1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
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C7H8N4O2
 1
1
Ki = 15100 nM
   TI
   LI
   LO
   TS
CP0099653
3-Methyl-1-(3-phenyl-propyl)-3,7-dihydro-purine-2,6-dione
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C15H16N4O2
 1
1
Ki = 15300 nM
   TI
   LI
   LO
   TS
CP0193365
7-(4-Chloro-butyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
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C11H15ClN4O2
 1
1
Ki = 18700 nM
   TI
   LI
   LO
   TS