Compound ID |
Compound Name |
Compound Formula |
CP0341603
|
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]pentanediamide
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|
C57H76N14O10
|
1
|
1 |
EC50 = 3.9 nM
|
|
|
CP0102963
|
6-(4-tert-butylphenyl)sulfonyl-7,8-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C25H26F3N3O2S
|
1
|
1 |
EC50 = 15 nM
|
|
|
CP0365995
|
4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H28N2O2
|
1
|
1 |
EC50 = 25 nM
|
|
|
CP0430445
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridin-2-amine
Show/Hide
|
C22H28N4
|
1
|
1 |
EC50 = 37 nM
|
|
|
CP0423561
|
6-(4-tert-butylphenyl)sulfonyl-2-chloro-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H26ClN3O2S
|
1
|
1 |
EC50 = 38 nM
|
|
|
CP0414267
|
7,8-dimethyl-6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C22H17F6N3O3S
|
1
|
1 |
EC50 = 43 nM
|
|
|
CP0402311
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)isothiazole
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|
C20H25N3S
|
1
|
1 |
EC50 = 44 nM
|
|
|
CP0225161
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
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|
C22H27N3
|
1
|
1 |
EC50 = 47 nM
|
|
|
CP0453510
|
7,8-dimethyl-6-(4-propan-2-ylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H24F3N3O2S
|
1
|
1 |
EC50 = 49 nM
|
|
|
CP0389466
|
6-(4-tert-butylphenyl)sulfonyl-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine-2-carbonitrile
Show/Hide
|
C25H26N4O2S
|
1
|
1 |
EC50 = 50 nM
|
|
|
CP0395607
|
6-(4-tert-butylphenyl)sulfonyl-7-methyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H24F3N3O2S
|
1
|
1 |
EC50 = 50 nM
|
|
|
CP0538376
|
2-[4-[[7,8-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-6-yl]sulfonyl]phenyl]-2-methylpropanenitrile
Show/Hide
|
C25H23F3N4O2S
|
1
|
1 |
EC50 = 60 nM
|
|
|
CP0390896
|
5-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)isothiazole
Show/Hide
|
C20H25N3S
|
1
|
1 |
EC50 = 63 nM
|
|
|
CP0462864
|
4'-(2-(4-(cyclohexylmethyl)-1H-imidazol-2-yl)ethyl)-4,5-difluorobiphenyl-2-carboxylic acid
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|
C25H26F2N2O2
|
1
|
1 |
EC50 = 63 nM
|
|
|
CP0441853
|
6-(4-tert-butylphenyl)sulfonyl-7-chloro-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C23H21ClF3N3O2S
|
1
|
1 |
EC50 = 63 nM
|
|
|
CP0401480
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-5-fluoropyridine
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|
C22H26FN3
|
1
|
1 |
EC50 = 66 nM
|
|
|
CP0523686
|
6-[4-(2-fluoropropan-2-yl)phenyl]sulfonyl-7,8-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H23F4N3O2S
|
1
|
1 |
EC50 = 69 nM
|
|
|
CP0441855
|
2-[6-(4-tert-butylphenyl)sulfonyl-7-fluoro-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-8-yl]propan-2-ol
Show/Hide
|
C26H27F4N3O3S
|
1
|
1 |
EC50 = 77 nM
|
|
|
CP0441859
|
6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-ol
Show/Hide
|
C23H22F3N3O3S
|
1
|
1 |
EC50 = 88 nM
|
|
|
CP0462865
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-6-methylpyridine
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|
C23H29N3
|
1
|
1 |
EC50 = 105 nM
|
|
|
CP0376662
|
10-(4-tert-butylphenyl)sulfonyl-5-(trifluoromethyl)-2,4,10,16-tetrazatetracyclo[9.8.0.03,8.012,17]nonadeca-1(11),3(8),4,6,12(17),13,15,18-octaene
Show/Hide
|
C26H23F3N4O2S
|
1
|
1 |
EC50 = 108 nM
|
|
|
CP0423563
|
6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C23H22F3N3O2S
|
1
|
1 |
EC50 = 110 nM
|
|
|
CP0441854
|
10-(4-tert-butylphenyl)sulfonyl-13-methyl-5-(trifluoromethyl)-2,4,10,12-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
Show/Hide
|
C23H23F3N4O2S
|
1
|
1 |
EC50 = 110 nM
|
|
|
CP0395609
|
7,8-dimethyl-2-(trifluoromethyl)-6-[5-(trifluoromethyl)thiophen-3-yl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C20H15F6N3O2S2
|
1
|
1 |
EC50 = 123 nM
|
|
|
CP0377000
|
3-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
Show/Hide
|
C22H27N3
|
1
|
1 |
EC50 = 131 nM
|
|
|
CP0423565
|
6-(4-tert-butylphenyl)sulfonyl-2,7,8-trimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C25H29N3O2S
|
1
|
1 |
EC50 = 131 nM
|
|
|
CP0402312
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-pyrazole
Show/Hide
|
C20H26N4
|
1
|
1 |
EC50 = 135 nM
|
|
|
CP0481364
|
7,8-dimethyl-2-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C22H17F6N3O2S
|
1
|
1 |
EC50 = 154 nM
|
|
|
CP0395608
|
7,8-dimethyl-2-(trifluoromethyl)-6-[5-(trifluoromethyl)thiophen-2-yl]sulfonyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C20H15F6N3O2S2
|
1
|
1 |
EC50 = 158 nM
|
|
|
CP0390895
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridin-2-ol
Show/Hide
|
C22H27N3O
|
1
|
1 |
EC50 = 169 nM
|
|
|
CP0410795
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)piperidine
Show/Hide
|
C22H33N3
|
1
|
1 |
EC50 = 171 nM
|
|
|
CP0400009
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinonitrile
Show/Hide
|
C23H26N4
|
1
|
1 |
EC50 = 193 nM
|
|
|
CP0377610
|
6-(4-tert-butylphenyl)sulfonyl-8-methyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H24F3N3O2S
|
1
|
1 |
EC50 = 199 nM
|
|
|
CP0497670
|
2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-6-methoxy-1H-benzo[d]imidazole
Show/Hide
|
C17H15ClN2O3
|
1
|
1 |
EC50 = 210 nM
|
|
|
CP0423562
|
4-tert-butyl-2-[[7,8-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-6-yl]sulfonyl]-1,3-thiazole
Show/Hide
|
C22H24F3N4O2S2+
|
1
|
1 |
EC50 = 216 nM
|
|
|
CP0493082
|
2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-6-(trifluoromethyl)-1H-benzo[d]imidazole
Show/Hide
|
C16H10ClF3N2O3
|
1
|
1 |
EC50 = 240 nM
|
|
|
CP0441856
|
6-(4-tert-butylphenyl)sulfonyl-2-chloro-3-fluoro-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H25ClFN3O2S
|
1
|
1 |
EC50 = 277 nM
|
|
|
CP0417715
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
Show/Hide
|
C22H27N3
|
1
|
1 |
EC50 = 305 nM
|
|
|
CP0395610
|
6-(4-tert-butylphenyl)sulfonyl-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H27N3O2S
|
1
|
1 |
EC50 = 325 nM
|
|
|
CP0493081
|
2-(1-(6-chlorobenzo[d][1,3]dioxol-5-yl)propan-2-yl)-6-methoxy-1H-benzo[d]imidazole
Show/Hide
|
C18H17ClN2O3
|
1
|
1 |
EC50 = 350 nM
|
|
|
CP0455893
|
2-((6-chlorobenzo[d][1,3]dioxol-5-yl)methylthio)-6-methoxy-1H-benzo[d]imidazole
Show/Hide
|
C16H13ClN2O3S
|
1
|
1 |
EC50 = 380 nM
|
|
|
CP0401489
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-2H-tetrazole
Show/Hide
|
C18H24N6
|
1
|
1 |
EC50 = 422 nM
|
|
|
CP0417714
|
2-(4-(2-(4-(cyclopentylmethyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
Show/Hide
|
C22H25N3
|
1
|
1 |
EC50 = 425 nM
|
|
|
CP0401483
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyrazine
Show/Hide
|
C21H26N4
|
1
|
1 |
EC50 = 431 nM
|
|
|
CP0474231
|
2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-6-methoxy-1H-benzo[d]imidazole
Show/Hide
|
C16H13ClN2O4
|
1
|
1 |
EC50 = 510 nM
|
|
|
CP0507291
|
4-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1,2,3-thiadiazole
Show/Hide
|
C19H24N4S
|
1
|
1 |
EC50 = 538 nM
|
|
|
CP0481277
|
7,8-dimethyl-6-(4-methylsulfonylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C22H20F3N3O4S2
|
1
|
1 |
EC50 = 543 nM
|
|
|
CP0528332
|
6-chloro-2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-1H-benzo[d]imidazole
Show/Hide
|
C15H10Cl2N2O3
|
1
|
1 |
EC50 = 570 nM
|
|
|
CP0390897
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-1,2,4-triazole
Show/Hide
|
C19H25N5
|
1
|
1 |
EC50 = 570 nM
|
|
|
CP0401488
|
1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-1H-1,2,3-triazole
Show/Hide
|
C19H25N5
|
1
|
1 |
EC50 = 641 nM
|
|
|
CP0401495
|
3-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinic acid
Show/Hide
|
C23H27N3O2
|
1
|
1 |
EC50 = 1263 nM
|
|
|
CP0144281
|
2-(3,5-dimethoxybenzylthio)-6-methoxy-1H-benzo[d]imidazole
Show/Hide
|
C17H18N2O3S
|
1
|
1 |
EC50 = 1600 nM
|
|
|
CP0309541
|
5-Methoxy-2-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethylsulfanyl)-1H-benzoimidazole
Show/Hide
|
C17H19N3O2S
|
1
|
1 |
EC50 = 3900 nM
|
|
|
CP0401496
|
6-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)picolinic acid
Show/Hide
|
C23H27N3O2
|
1
|
1 |
EC50 = 5234 nM
|
|
|
CP0423564
|
6-(4-tert-butylphenyl)sulfonyl-9,10-dimethyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C25H26F3N3O2S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0441858
|
6-(4-tert-butylphenyl)sulfonyl-3-chloro-7,8-dimethyl-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C24H26ClN3O2S
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0017654
|
(RS)-6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl) methylsulfinyl)-1H-benzo[d]imidazole
Show/Hide
|
C17H19N3O3S
|
1
|
1 |
EC50 = 14000 nM
|
|
|
CP0340376
|
6-methoxy-2-(naphthalen-2-ylmethylthio)-1H-benzo[d]imidazole
Show/Hide
|
C19H16N2OS
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0398619
|
2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-6-methoxybenzo[d]thiazole
Show/Hide
|
C17H14ClNO3S
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0398620
|
6-chloro-2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-5-methyl-1H-benzo[d]imidazole
Show/Hide
|
C16H12Cl2N2O3
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0422294
|
2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-5-methoxybenzo[d]thiazole
Show/Hide
|
C17H14ClNO3S
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0440664
|
2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-6-phenoxy-1H-benzo[d]imidazole
Show/Hide
|
C21H15ClN2O4
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0474232
|
2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-6-methoxybenzo[d]oxazole
Show/Hide
|
C17H14ClNO4
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0492680
|
2-(3,4-difluorobenzylthio)-6-methoxy-1H-benzo[d]imidazole
Show/Hide
|
C15H12F2N2OS
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0526658
|
6-chloro-N-(6-methoxy-1H-benzo[d]imidazol-2-yl)benzo[d][1,3]dioxole-5-carboxamide
Show/Hide
|
C16H12ClN3O4
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0526772
|
3-((6-methoxy-1H-benzo[d]imidazol-2-ylthio)methyl)-1H-indazole
Show/Hide
|
C16H14N4OS
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0527030
|
N-[(6-chloro-1,3-benzodioxol-5-yl)methyl]-6-methoxy-1H-benzimidazol-2-amine
Show/Hide
|
C16H14ClN3O3
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0532014
|
6-methoxy-2-(pyridin-4-ylmethylthio)-1H-benzo[d]imidazole
Show/Hide
|
C14H13N3OS
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0553683
|
2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)ethyl)-5-methoxybenzo[d]oxazole
Show/Hide
|
C17H14ClNO4
|
1
|
1 |
EC50 > 32000 nM
|
|
|
CP0869977
|
2-(2-(6-chlorobenzo[d][1,3]dioxol-5-yl)vinyl)-6-methoxy-1H-benzo[d]imidazole
Show/Hide
|
C17H13ClN2O3
|
1
|
1 |
EC50 > 32000 nM
|
|
|