Brief Information of the Compound and Protein
Compound Name
4'-(2-(4-(cyclohexylmethyl)-1H-imidazol-2-yl)ethyl)-4,5-difluorobiphenyl-2-carboxylic acid
    Show/Hide
PubChem ID
CID: 46885311
Canonical SMILES
OC(=O)c1cc(F)c(F)cc1-c1ccc(CCc2ncc(CC3CCCCC3)[nH]2)cc1
    Show/Hide
Compound Formula C25H26F2N2O2
Compound Structure
Protein Name
Bombesin receptor subtype-3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
GRP-related receptor
Uniprot ID
P32247
Gene Name
BRS3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000943 CellSensor NFAT-bla CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 63 nM
   TI
   LI
   LO
   TS