Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01823 , Prostaglandin F2-alpha receptor
 Protein Info 
Gene Name PTGFR
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P43088
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01823
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0512768
 Compound Info 
6-bromo-N-[2-(2-methoxyphenyl)propyl]-3-methyl-2-phenylquinoline-4-carboxamide
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C27H25BrN2O2
  1
1
IC50 < 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0272414
 Compound Info 
US11149018, Example 34
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C26H27BrClN3O3
  2
1
IC50 = 22 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
Ki = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0471861
 Compound Info 
6-bromo-3-methyl-N-(2-pyridin-3-ylethyl)-2-thiophen-2-ylquinoline-4-carboxamide
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C22H18BrN3OS
  1
1
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0422463
 Compound Info 
1-(2,6-dimethoxyphenyl)-N-[[3-methyl-4-[6-oxo-5,9-bis(2,2,2-trifluoroethoxy)-8H-pyrrolo[3,4-g]quinolin-7-yl]phenyl]methylsulfonyl]cyclopropane-1-carboxamide
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C35H31F6N3O8S
  1
1
Ki = 340 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0393748
 Compound Info 
N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-(2-methoxyphenyl)acetamide
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C32H33N3O7S
  1
1
Ki = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0343798
 Compound Info 
2-[(3R)-4-[(4-chlorophenyl)methyl]-7-fluoro-5-methylsulfonyl-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
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C21H19ClFNO4S
  1
1
Ki = 9991 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0374187
 Compound Info 
2-[(3R)-5-bromo-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
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C20H16BrClFNO2
  1
1
Ki = 14000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0041889
 Compound Info 
2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
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C23H24ClNO5S
  1
1
Ki > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0108218
 Compound Info 
(R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
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C23H22ClNO5S
  1
1
Ki > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0372074
 Compound Info 
2-[(3R)-5-acetyl-4-[(4-chlorophenyl)methyl]-7-fluoro-2,3-dihydro-1H-cyclopenta[b]indol-3-yl]acetic acid
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C22H19ClFNO3
  1
1
Ki > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS