Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US11149018, Example 34
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 PubChem ID
CID: 146368333
Canonical SMILES
Cc1c(nc2ccc(Br)cc2c1C(=O)NC[C@H](CCC(O)=O)c1ccccc1Cl)N1CCCC1
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Compound Formula C26H27BrClN3O3
Compound Structure
Protein Name
 Protein Info 
Prostaglandin F2-alpha receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P43088
Gene Name
PTGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
2
Ki = 16 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 ~ 11 nM
2 IC50 ~ 21 nM
3 IC50 ~ 22 nM
4 Ki ~ 14.8 nM