Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01592 , Dual specificity tyrosine-phosphorylation-regulated kinase 1A
 Protein Info 
Gene Name DYRK1A
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q13627
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01592
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0073979
 Compound Info 
N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine
   Show/Hide
C24H27N7O
  1
1
IC50 = 153 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099035
 Compound Info 
(3E)-3-(1,3-benzothiazol-6-ylmethylidene)oxolan-2-one
   Show/Hide
C12H9NO2S
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0019844
 Compound Info 
7-methoxy-1-methyl-9H-beta-carboline;hydrochloride
   Show/Hide
C13H12N2O
  1
1
IC50 = 400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0546502
 Compound Info 
4-[5-[(2-aminophenyl)methylcarbamoyl]thiophen-2-yl]-1-benzothiophene-2-carboxamide
   Show/Hide
C21H17N3O2S2
  1
1
IC50 = 1100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0102176
 Compound Info 
(5Z)-5-(quinolin-6-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
   Show/Hide
C13H8N2OS2
  1
1
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0672481
 Compound Info 
SID90341202
   Show/Hide
C12H7N3O2S
  1
1
IC50 = 1600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0546860
 Compound Info 
4-[5-[(2-aminophenyl)methylcarbamoyl]thiophen-2-yl]-5-chloro-1-benzothiophene-2-carboxamide
   Show/Hide
C21H16ClN3O2S2
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0835393
 Compound Info 
CmpdA
   Show/Hide
C20H14ClN3O2S2
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0075817
 Compound Info 
(5Z)-5-(1,3-benzothiazol-6-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
   Show/Hide
C11H6N2OS3
  1
1
IC50 = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0102174
 Compound Info 
(3E)-3-(2,3-dihydro-1-benzofuran-5-ylmethylidene)-5-methyloxolan-2-one
   Show/Hide
C14H14O3
  1
1
IC50 = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0550092
 Compound Info 
4-[5-[(4-aminophenyl)methylcarbamoyl]thiophen-2-yl]-1-benzothiophene-2-carboxamide
   Show/Hide
C21H17N3O2S2
  1
1
IC50 = 2700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0567741
 Compound Info 
4-[5-[(2-hydroxyphenyl)methylcarbamoyl]thiophen-2-yl]-1-benzothiophene-2-carboxamide
   Show/Hide
C21H16N2O3S2
  1
1
IC50 = 4400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569737
 Compound Info 
4-[5-(benzylcarbamoyl)thiophen-2-yl]-1-benzothiophene-2-carboxamide
   Show/Hide
C21H16N2O2S2
  1
1
IC50 = 4600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS