Brief Information of the Compound and Protein
Compound Name
7-methoxy-1-methyl-9H-beta-carboline;hydrochloride
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PubChem ID
CID: 5280953
SID: 12015642
Canonical SMILES
COc1ccc2c(c1)[nH]c1c(C)nccc21
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Compound Formula C13H12N2O
Compound Structure
Protein Name
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase DYRK family
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CMGC protein kinase Dyrk1 subfamily
Uniprot ID
Q13627
Gene Name
DYRK1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8.81 nM
2 IC50 = 21.83 nM
3 IC50 = 27 nM
4 IC50 = 29 nM
5 IC50 = 30 nM
6 IC50 = 32 nM
7 IC50 = 33 nM
8 IC50 = 56 nM
9 IC50 = 60 nM
10 IC50 = 80 nM