Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01425 , Poly [ADP-ribose] polymerase tankyrase-2
 Protein Info 
Gene Name TNKS2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9H2K2
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01425
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0155059
 Compound Info 
1-[3-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxo-3H-benzimidazole-5-carbonitrile
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C24H17ClN8O
  1
1
IC50 = 19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0468769
 Compound Info 
1-[4-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclohexyl]-2-oxo-3H-benzimidazole-5-carbonitrile
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C26H21ClN8O
  1
1
IC50 = 120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513932
 Compound Info 
3-[3-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-1H-benzimidazol-2-one
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C23H18ClN7O
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0273375
 Compound Info 
3-[4-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclohexyl]-1H-benzimidazol-2-one
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C25H22ClN7O
  1
1
IC50 = 1060 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0273376
 Compound Info 
1-[4-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]phenyl]-2-oxo-3H-benzimidazole-5-carbonitrile
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C26H15ClN8O
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS