Brief Information of the Compound and Protein
Compound Name
3-[4-[4-(2-chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclohexyl]-1H-benzimidazol-2-one
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Canonical SMILES
Clc1ccccc1-n1c(nnc1-c1ccncn1)[C@H]1CC[C@@H](CC1)n1c2ccccc2[nH]c1=O
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Compound Formula C25H22ClN7O
Compound Structure
Protein Name
Poly [ADP-ribose] polymerase tankyrase-2
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q9H2K2
Gene Name
TNKS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1060 nM
   TI
   LI
   LO
   TS
CL000015 SW480 Homo sapiens (Human)  1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 430 nM