| Compound ID |
Compound Name |
Compound Formula |
|
CP0044356
|
6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-(4-methylpiperazine-1-carbonyl)phenyl]pyridazine-3-carboxamide
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|
C25H25Cl2FN6O3
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0461554
|
US9126947, 15
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|
C26H27Cl2FN6O3
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0538884
|
US9126947, 13
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|
C27H27Cl2FN6O3
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0545652
|
US9126947, 17
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|
C26H27Cl2FN6O3
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0545653
|
US9126947, 18
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|
C26H27Cl2FN6O3
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0554645
|
US9126947, 16
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|
C25H25Cl2FN6O3
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0540860
|
N-[(1S)-1-(2,4-difluorophenyl)ethyl]-3-(5-methyl-1H-pyrazol-3-yl)imidazo[1,2-b]pyridazin-6-amine
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|
C18H16F2N6
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0556482
|
3-(3,6-dihydro-2H-pyran-4-yl)-N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridin-6-amine
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|
C23H23FN6O
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0553003
|
N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-1-(5-methyl-1H-pyrazol-3-yl)-3-methylsulfonylpyrrolo[2,3-b]pyridin-6-amine
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|
C19H19FN6O2S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0438057
|
6-[[(1S)-1-(5-fluoropyridin-2-yl)ethyl]amino]-N,N-dimethyl-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridine-3-carboxamide
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|
C21H22FN7O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0553999
|
[6-[[(1S)-1-(5-fluoropyridin-2-yl)ethyl]amino]-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridin-3-yl]-morpholin-4-ylmethanone
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|
C23H24FN7O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0064301
|
[6-[(1S)-1-(5-fluoropyridin-2-yl)ethoxy]-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridin-3-yl]-[(2S)-2-methylmorpholin-4-yl]methanone
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|
C24H25FN6O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0556480
|
N-[(1S)-1-(2,4-difluorophenyl)ethyl]-1-(5-methyl-1H-pyrazol-3-yl)-3-methylsulfonylpyrrolo[2,3-b]pyridin-6-amine
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|
C20H19F2N5O2S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0031719
|
(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
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|
C21H22Cl2FN5O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0540862
|
[6-[[(1S)-1-(5-fluoropyridin-2-yl)ethyl]amino]-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridin-3-yl]-(4-methylpiperazin-1-yl)methanone
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|
C24H27FN8O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0556481
|
3-ethylsulfonyl-N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridin-6-amine
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|
C20H21FN6O2S
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0384473
|
[6-[(1R)-1-(5-fluoropyridin-2-yl)ethoxy]-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridin-3-yl]-[(2R)-2-methylmorpholin-4-yl]methanone
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|
C24H25FN6O3
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0533011
|
N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-1-(5-methyl-1H-pyrazol-3-yl)-3-(oxetan-3-ylsulfonyl)pyrrolo[2,3-b]pyridin-6-amine
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|
C21H21FN6O3S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
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CP0540859
|
[6-[1-(5-fluoropyridin-2-yl)ethoxy]-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridin-3-yl]-morpholin-4-ylmethanone
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|
C23H23FN6O3
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0528480
|
N-[(1S)-1-(2,4-difluorophenyl)ethyl]-1-(5-methyl-1H-pyrazol-3-yl)pyrrolo[2,3-b]pyridin-6-amine
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|
C19H17F2N5
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0540861
|
N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-1-(5-methyl-1H-pyrazol-3-yl)-3-propan-2-ylsulfonylpyrrolo[2,3-b]pyridin-6-amine
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|
C21H23FN6O2S
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0134636
|
(7R)-2-[2-ethoxy-4-(1-methylpiperidin-4-yl)anilino]-7-ethyl-5-methyl-8-[(4-methylthiophen-2-yl)methyl]-7H-pteridin-6-one
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|
C29H38N6O2S
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0044060
|
4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
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|
C28H39N7O3
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0142866
|
(7R)-2-[2-ethoxy-4-(1-methylpiperidin-4-yl)anilino]-7-ethyl-5-methyl-8-[(3-methylthiophen-2-yl)methyl]-7H-pteridin-6-one
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|
C29H38N6O2S
|
1
|
| 1 |
IC50 = 1020 nM
|
|
|
|
CP0350379
|
(7R)-8-benzyl-2-[2-ethoxy-4-(1-methylpiperidin-4-yl)anilino]-7-ethyl-5-methyl-7H-pteridin-6-one
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|
C30H38N6O2
|
1
|
| 1 |
IC50 = 1640 nM
|
|
|
|
CP0113988
|
CEP-32496
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|
C24H22F3N5O5
|
1
|
| 1 |
Kd > 10000 nM
|
|
|
