Brief Information of the Compound and Protein
Compound Name
N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-1-(5-methyl-1H-pyrazol-3-yl)-3-(oxetan-3-ylsulfonyl)pyrrolo[2,3-b]pyridin-6-amine
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PubChem ID
CID: 138105933
Canonical SMILES
C[C@H](Nc1ccc2c(cn(-c3cc(C)[nH]n3)c2n1)S(=O)(=O)C1COC1)c1ccc(F)cn1
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Compound Formula C21H21FN6O3S
Compound Structure
Protein Name
ALK tyrosine kinase receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS