Compound ID |
Compound Name |
Compound Formula |
CP0498201
|
[4-(3,4-difluoroanilino)piperidin-1-yl]-[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridin-2-yl]methanone
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|
C30H35F2N5O
|
1
|
1 |
EC50 = 1.995 nM
|
|
|
CP0401369
|
[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]-[4-(4-fluoroanilino)piperidin-1-yl]methanone
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|
C31H37FN4O
|
1
|
1 |
EC50 = 2.512 nM
|
|
|
CP0471932
|
N-[[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-N-methyl-2-phenylsulfanylacetamide
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|
C29H35N3OS
|
1
|
1 |
EC50 = 3.162 nM
|
|
|
CP0498202
|
[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]-3-fluorophenyl]pyridin-2-yl]-[4-(4-fluoroanilino)piperidin-1-yl]methanone
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|
C30H35F2N5O
|
1
|
1 |
EC50 = 3.981 nM
|
|
|
CP0230639
|
(4-anilinopiperidin-1-yl)-[2-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methanone
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|
C31H38N4O
|
1
|
1 |
EC50 = 5.012 nM
|
|
|
CP0538040
|
[3-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]-3-methoxyphenyl]pyridin-2-yl]-[4-(4-fluoroanilino)piperidin-1-yl]methanone
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|
C31H38FN5O2
|
1
|
1 |
EC50 = 5.012 nM
|
|
|
CP0505221
|
[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridin-2-yl]-[4-(3-fluoroanilino)piperidin-1-yl]methanone
Show/Hide
|
C30H36FN5O
|
1
|
1 |
EC50 = 6.31 nM
|
|
|
CP0276373
|
4'-((3R,5S)-3,5-Dimethyl-piperazin-1-ylmethyl)-biphenyl-2-carboxylic acid ethyl-phenethyl-amide
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|
C30H37N3O
|
1
|
1 |
EC50 = 7.943 nM
|
|
|
CP0095130
|
[2-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]methanone
Show/Hide
|
C32H38FN3O
|
1
|
1 |
EC50 = 10 nM
|
|
|
CP0320332
|
[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridin-2-yl]-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]methanone
Show/Hide
|
C31H37FN4O
|
1
|
1 |
EC50 = 10 nM
|
|
|
CP0364569
|
2-Benzenesulfonyl-N-[4'-((3R,5S)-3,5-dimethyl-piperazin-1-ylmethyl)-biphenyl-2-ylmethyl]-N-methyl-acetamide
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|
C29H35N3O3S
|
1
|
1 |
EC50 = 10 nM
|
|
|
CP0547803
|
[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]-3-fluorophenyl]pyridin-2-yl]-[4-(3-fluoroanilino)piperidin-1-yl]methanone
Show/Hide
|
C30H35F2N5O
|
1
|
1 |
EC50 = 10 nM
|
|
|
CP0035879
|
[1-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]imidazol-2-yl]-[4-(3-fluoroanilino)piperidin-1-yl]methanone
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|
C28H35FN6O
|
1
|
1 |
EC50 = 15.85 nM
|
|
|
CP0035877
|
(3-(4-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)phenyl)pyridin-2-yl)(4-(4-fluorophenylamino)piperidin-1-yl)methanone
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|
C30H36FN5O
|
1
|
1 |
EC50 = 19.95 nM
|
|
|
CP0498200
|
3-[[1-[3-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridine-2-carbonyl]piperidin-4-yl]amino]benzonitrile
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|
C31H36N6O
|
1
|
1 |
EC50 = 19.95 nM
|
|
|
CP0547802
|
N-[[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-N-methyl-2-[(4-methylphenyl)sulfonylamino]acetamide
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|
C30H38N4O3S
|
1
|
1 |
EC50 = 19.95 nM
|
|
|
CP0498974
|
N-[[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-2-(4-fluorophenoxy)-N-methylacetamide
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|
C29H34FN3O2
|
1
|
1 |
EC50 = 31.62 nM
|
|
|
CP0131787
|
3-Cyclohexyl-1-[4'-((3R,5S)-3,5-dimethyl-piperazin-1-ylmethyl)-biphenyl-2-ylmethyl]-1-[2-(3-methoxy-phenyl)-ethyl]-urea
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|
C36H48N4O2
|
1
|
1 |
EC50 = 50.12 nM
|
|
|
CP0167645
|
[4-(4-chloroanilino)piperidin-1-yl]-[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methanone
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|
C31H37ClN4O
|
1
|
1 |
EC50 = 50.12 nM
|
|
|
CP0511949
|
[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridin-2-yl]-[4-(2-fluoroanilino)piperidin-1-yl]methanone
Show/Hide
|
C30H36FN5O
|
1
|
1 |
EC50 = 50.12 nM
|
|
|
CP0538039
|
N-[[2-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-2-(4-fluorophenyl)-N-methylacetamide
Show/Hide
|
C29H34FN3O
|
1
|
1 |
EC50 = 50.12 nM
|
|
|
CP0136344
|
[1-[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]benzoyl]piperidin-4-yl]-(4-fluorophenyl)methanone
Show/Hide
|
C32H36FN3O2
|
1
|
1 |
EC50 = 63.1 nM
|
|
|
CP0230640
|
[2-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]-[4-(4-fluorophenoxy)piperidin-1-yl]methanone
Show/Hide
|
C31H36FN3O2
|
1
|
1 |
EC50 = 63.1 nM
|
|
|
CP0035870
|
N-[[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-N-methyl-2-phenoxyacetamide
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|
C29H35N3O2
|
1
|
1 |
EC50 = 79.43 nM
|
|
|
CP0320333
|
2-(3-Chloro-phenyl)-N-[4'-((3R,5S)-3,5-dimethyl-piperazin-1-ylmethyl)-biphenyl-2-ylmethyl]-N-methyl-acetamide
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|
C29H34ClN3O
|
1
|
1 |
EC50 = 79.43 nM
|
|
|
CP0418599
|
3-cyclohexyl-1-[2-(3-methoxyphenyl)ethyl]-1-[[2-[4-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]urea
Show/Hide
|
C34H44N4O2
|
1
|
1 |
EC50 = 100 nM
|
|
|
CP0372334
|
N-[2-(3-methoxyphenyl)ethyl]-2-phenoxy-N-[[2-[4-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]acetamide
Show/Hide
|
C35H39N3O3
|
1
|
1 |
EC50 = 251.19 nM
|
|
|
CP0471933
|
N-[[2-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-N,4-dimethylpentanamide
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|
C27H39N3O
|
1
|
1 |
EC50 = 251.19 nM
|
|
|
CP0496210
|
N-(3-methoxypropyl)-2-phenoxy-N-[[2-[4-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]acetamide
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|
C30H37N3O3
|
1
|
1 |
EC50 = 398.11 nM
|
|
|
CP0517057
|
[2-[5-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]-1,3-thiazol-2-yl]phenyl]-[4-(4-fluoroanilino)piperidin-1-yl]methanone
Show/Hide
|
C28H34FN5OS
|
1
|
1 |
EC50 = 398.11 nM
|
|
|
CP0515822
|
3-cyclohexyl-1-(3-methoxypropyl)-1-[[2-[4-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]urea
Show/Hide
|
C29H42N4O2
|
1
|
1 |
EC50 = 501.19 nM
|
|
|
CP0494563
|
N-(3-methoxypropyl)-N-[[2-[4-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]acetamide
Show/Hide
|
C24H33N3O2
|
1
|
1 |
EC50 = 630.96 nM
|
|
|
CP0510508
|
4-fluoro-N-(3-methoxypropyl)-N-[[2-[4-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzenesulfonamide
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|
C28H34FN3O3S
|
1
|
1 |
EC50 = 630.96 nM
|
|
|
CP0055087
|
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
Show/Hide
|
C37H67NO13
|
1
|
1 |
EC50 = 630.96 nM
|
|
|
CP0498199
|
4-[[1-[3-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridine-2-carbonyl]piperidin-4-yl]amino]benzonitrile
Show/Hide
|
C31H36N6O
|
1
|
1 |
EC50 = 630.96 nM
|
|
|
CP0522114
|
2-[[1-[3-[4-[[(3S,5R)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridine-2-carbonyl]piperidin-4-yl]amino]benzonitrile
Show/Hide
|
C31H36N6O
|
1
|
1 |
EC50 = 794.33 nM
|
|
|
CP0491298
|
N-[2-(3-methoxyphenyl)ethyl]-2-phenyl-N-[[2-[4-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]acetamide
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|
C35H39N3O2
|
1
|
1 |
EC50 = 1000 nM
|
|
|
CP0095129
|
N-[[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-N-methyl-2-(3-methyl-1,2-oxazol-5-yl)acetamide
Show/Hide
|
C27H34N4O2
|
1
|
1 |
EC50 = 1000 nM
|
|
|
CP0516040
|
[3-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridin-2-yl]-[4-(4-methoxyanilino)piperidin-1-yl]methanone
Show/Hide
|
C31H39N5O2
|
1
|
1 |
EC50 = 1000 nM
|
|
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CP0504206
|
3-cyclohexyl-1-(2-phenylethyl)-1-[[2-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]urea
Show/Hide
|
C33H42N4O
|
1
|
1 |
EC50 = 1584.89 nM
|
|
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CP0479353
|
4-[[1-[3-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyridine-2-carbonyl]piperidin-4-yl]amino]benzamide
Show/Hide
|
C31H38N6O2
|
1
|
1 |
EC50 = 2511.89 nM
|
|
|
CP0517058
|
[1-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]pyrrolidin-2-yl]-[4-(3-fluoroanilino)piperidin-1-yl]methanone
Show/Hide
|
C29H40FN5O
|
1
|
1 |
EC50 = 2511.89 nM
|
|
|
CP0522406
|
2-(3-methoxyphenyl)-N-[[2-[4-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]ethanamine
Show/Hide
|
C27H33N3O
|
1
|
1 |
EC50 = 5011.87 nM
|
|
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CP0498198
|
N-[1-[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]benzoyl]piperidin-4-yl]-4-fluorobenzamide
Show/Hide
|
C32H37FN4O2
|
1
|
1 |
EC50 > 10000 nM
|
|
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CP0517056
|
[2-[5-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]pyridin-2-yl]phenyl]-[4-(4-fluoroanilino)piperidin-1-yl]methanone
Show/Hide
|
C30H36FN5O
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0245273
|
4-fluoro-N-[[3-[(3-nitrophenyl)methyl-(2,2,2-trichloroacetyl)amino]cyclohexyl]methyl]-N-[3-(2-pyrrolidin-1-ylethoxy)phenyl]benzamide
Show/Hide
|
C35H38Cl3FN4O5
|
1
|
1 |
IC50 = 52 nM
|
|
|
CP0153657
|
N-[[3-[(3-chlorophenyl)methyl-(2,2,2-trichloroacetyl)amino]cyclohexyl]methyl]-4-fluoro-N-[3-(2-piperidin-1-ylethoxy)phenyl]benzamide
Show/Hide
|
C36H40Cl4FN3O3
|
1
|
1 |
IC50 = 228 nM
|
|
|
CP0274921
|
N-[[3-[(3-chlorophenyl)methyl-(2,2,2-trichloroacetyl)amino]cyclohexyl]methyl]-4-fluoro-N-[3-(2-pyrrolidin-1-ylethoxy)phenyl]benzamide
Show/Hide
|
C35H38Cl4FN3O3
|
1
|
1 |
IC50 = 267 nM
|
|
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CP0153658
|
N-[[(1S,3R)-3-[benzyl(2,2-dimethylpropanoyl)amino]cyclohexyl]methyl]-4-fluoro-N-[3-(2-pyrrolidin-1-ylethoxy)phenyl]benzamide
Show/Hide
|
C38H48FN3O3
|
1
|
1 |
IC50 = 338 nM
|
|
|
CP0288441
|
N-[[3-[benzyl(2,2-dimethylpropanoyl)amino]cyclohexyl]methyl]-4-fluoro-N-[3-(2-pyrrolidin-1-ylethoxy)phenyl]benzamide
Show/Hide
|
C38H48FN3O3
|
1
|
1 |
IC50 = 990 nM
|
|
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CP0131898
|
N-[[(1R,3S)-3-[benzyl(2,2-dimethylpropanoyl)amino]cyclohexyl]methyl]-4-fluoro-N-[3-(2-pyrrolidin-1-ylethoxy)phenyl]benzamide
Show/Hide
|
C38H48FN3O3
|
1
|
1 |
IC50 = 2480 nM
|
|
|