Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT01101 , Insulin receptor
 Protein Info 
Gene Name INSR
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P06213
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT01101
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0095983
 Compound Info 
(1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol
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C26H23N5O
  1
1
IC50 = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0029933
 Compound Info 
1-[4-[3-[4-amino-5-[2-fluoro-3-[[(2S)-oxolan-2-yl]methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
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C27H33FN6O3
  1
1
IC50 = 102 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0029934
 Compound Info 
1-[4-[3-[4-amino-5-[2-fluoro-5-[[(2S)-oxolan-2-yl]methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
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C27H33FN6O3
  1
1
IC50 = 166 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0017667
 Compound Info 
7-[3-(azetidin-1-ylmethyl)cyclobutyl]-5-[3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]pyrrolo[2,3-d]pyrimidin-4-amine
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C27H33N5O2
  1
1
IC50 = 471 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0029932
 Compound Info 
7-[3-(azetidin-1-ylmethyl)cyclobutyl]-5-(3-phenylmethoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
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C27H29N5O
  1
1
IC50 = 892 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0031719
 Compound Info 
(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
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C21H22Cl2FN5O
  1
1
IC50 = 2887 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0113988
 Compound Info 
CEP-32496
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C24H22F3N5O5
  1
1
Kd > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS