Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT00980 , Aurora kinase A
Gene Name AURKA
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID O14965
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT00980
 
Compound ID Compound Name Compound Formula
CP0178025
2-[(3R)-3-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
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C27H29F2N9O2S
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0178029
(3R)-N-cyclopentyl-1-[2-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylanilino]-2-oxoethyl]pyrrolidine-3-carboxamide
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C28H33N9O2S
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0113988
CEP-32496
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C24H22F3N5O5
 1
1
Kd > 10000 nM
   TI
   LI
   LO
   TS