Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT00827 , 5-hydroxytryptamine receptor 1D
Gene Name HTR1D
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P28221
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT00827
 
Compound ID Compound Name Compound Formula
CP0196504
[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
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C13H15F3N2O3S
 1
1
IC50 = 8.4 nM
   TI
   LI
   LO
   TS
CP0332330
[3-[2-(diethylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
   Show/Hide
C15H19F3N2O3S
 1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
CP0466096
N,N-dimethyl-2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
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C19H22N2O
 1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
CP0421471
3-(2-Diethylamino-ethyl)-1H-indol-5-ol
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C14H20N2O
 1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS
CP0421474
N,N-diethyl-2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
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C21H26N2O
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0036796
[3-[2-(dipropylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
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C17H23F3N2O3S
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0481162
N-[2-(5-phenylmethoxy-1H-indol-3-yl)ethyl]-N-propylpropan-1-amine
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C23H30N2O
 1
1
IC50 = 470 nM
   TI
   LI
   LO
   TS
CP0133551
3-(2-Dipropylamino-ethyl)-1H-indol-5-ol
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C16H24N2O
 1
1
IC50 = 820 nM
   TI
   LI
   LO
   TS
CP0446013
(S)-1-(2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-N-methyl-3,4-dihydro-1H-isochromene-6-carboxamide
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C24H31N3O3
 1
1
Ki = 0.9 nM
   TI
   LI
   LO
   TS
CP0005653
(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
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C14H21N3O2S
 1
1
Ki = 2 nM
   TI
   LI
   LO
   TS
CP0449615
(S)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
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C23H29N3O3
 1
1
Ki = 3.8 nM
   TI
   LI
   LO
   TS
CP0391252
1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-piperazine
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C22H28N2O2
 1
1
Ki = 6.7 nM
   TI
   LI
   LO
   TS
CP0402145
1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
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C23H29N3O3
 1
1
Ki = 8.6 nM
   TI
   LI
   LO
   TS
CP0456120
3-(4-methylphenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
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C14H16N2O
 1
1
Ki = 147 nM
   TI
   LI
   LO
   TS
CP0391904
3-(4-methylphenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
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C14H17N3
 1
1
Ki = 165 nM
   TI
   LI
   LO
   TS
CP0403969
(R)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
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C23H29N3O3
 1
1
Ki = 238 nM
   TI
   LI
   LO
   TS
CP0498120
(R)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid methylamide
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C24H31N3O3
 1
1
Ki = 298 nM
   TI
   LI
   LO
   TS
CP0391906
3-(4-fluorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
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C13H14FN3
 1
1
Ki = 636 nM
   TI
   LI
   LO
   TS
CP0635067
2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride
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C8H9Cl2N3
 1
1
Ki = 684 nM
   TI
   LI
   LO
   TS
CP0370584
4-(2-bromo-6-piperazin-1-ylpyridin-4-yl)sulfonylaniline
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C15H17BrN4O2S
 1
1
Ki = 1122.02 nM
   TI
   LI
   LO
   TS
CP0391901
3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine
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C13H14ClN3
 1
1
Ki = 2112 nM
   TI
   LI
   LO
   TS
CP0372923
2-[3-[(2S,5S)-5-[(6-bromo-1H-indol-3-yl)methyl]-3,6-dioxopiperazin-2-yl]propyl]guanidine
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C17H21BrN6O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0845072
(cyclo[(6-bromo-8-entryptophan)arginine])
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C17H19BrN6O2
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391907
3-(4-chlorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
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C13H13ClN2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0391908
3-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-[1,2]oxazolo[4,5-d]azepine
   Show/Hide
C13H13FN2O
 1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
CP0040453
CAS_3277600
   Show/Hide
C14H14N4OS
 1
1
Ki < 10000 nM
   TI
   LI
   LO
   TS
CP0415376
4-(4-aminophenyl)sulfonyl-6-bromo-N-methylpyridin-2-amine
   Show/Hide
C12H12BrN3O2S
 1
1
Ki < 10000 nM
   TI
   LI
   LO
   TS
CP0874735
4-Amino-N-(2,6-bis-methylamino-pyrimidin-4-yl)-benzenesulfonamide dihydrobromide
   Show/Hide
C12H18Br2N6O2S
 1
1
Ki < 10000 nM
   TI
   LI
   LO
   TS
CP0370117
4-(2-Bromo-6-pyrrolidin-1-yl-pyridine-4-sulfonyl)-phenylamine
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C15H16BrN3O2S
 1
1
Ki < 100000 nM
   TI
   LI
   LO
   TS