Brief Information of the Cell Line and Protein
Cell Line ID: CL000004 , SH-SY5Y
Synonyms
SH-Sy5y
SHSY5Y
SHSY-5Y
SK-SH-SY5Y
SY5Y
SH-SY5Y Parental
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0019
Protein ID: PT01555 , Oxysterols receptor LXR-alpha
Gene Name NR1H3
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q13133
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000004  Protein ID: PT01555
 
Compound ID Compound Name Compound Formula
CP0003740
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
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C17H12F9NO3S
 1
1
EC50 = 85 nM
   TI
   LI
   LO
   TS
CP0006936
2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid
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C33H31ClF3NO3
 1
1
EC50 = 310 nM
   TI
   LI
   LO
   TS
CP0198576
(S)-N-(2-chloro-4-(2-chloro-N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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C17H15Cl2F3N2O4S
 1
1
EC50 = 1820 nM
   TI
   LI
   LO
   TS
CP0259299
methyl 4-[[3-chloro-4-[(3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl)amino]phenyl]-methylsulfamoyl]benzoate
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C19H18ClF3N2O6S
 1
1
EC50 = 3610 nM
   TI
   LI
   LO
   TS
CP0259296
(S)-N-(2-chloro-4-(N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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C17H16ClF3N2O4S
 1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0371199
N-[2-chloro-4-[(4-cyanophenyl)sulfonyl-methylamino]phenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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C18H15ClF3N3O4S
 1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0435156
(S)-N-(2-chloro-4-(N,4-dimethylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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C18H18ClF3N2O4S
 1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0259297
N-[2-chloro-4-[(2-chlorophenyl)sulfonyl-ethylamino]phenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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C18H17Cl2F3N2O4S
 1
1
EC50 = 8500 nM
   TI
   LI
   LO
   TS
CP0198578
methyl 3-[4-[[3-chloro-4-[(3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl)amino]phenyl]-methylsulfamoyl]phenyl]propanoate
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C21H22ClF3N2O6S
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0214923
N-[2-chloro-4-[(2-chlorophenyl)sulfonyl-prop-2-enylamino]phenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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C19H17Cl2F3N2O4S
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0214925
4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)benzoic acid
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C18H16ClF3N2O6S
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0262779
3-(4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)phenyl)propanoic acid
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C20H20ClF3N2O6S
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0285586
N-[2-chloro-4-[(2-chlorophenyl)sulfonyl-(cyclopropylmethyl)amino]phenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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C20H19Cl2F3N2O4S
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0344790
N-[4-[benzyl-(2-chlorophenyl)sulfonylamino]-2-chlorophenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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C23H19Cl2F3N2O4S
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS