| Compound ID |
Compound Name |
Compound Formula |
|
CP0470161
|
US9000182, 11, isomer 1
Show/Hide
|
C21H26F3N3O2
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0500326
|
US9000182, 9, isomer 1
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0459860
|
US9000183, 6 Isomer 1
Show/Hide
|
C25H24ClFN4O
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0469769
|
US9000185, 8
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0459862
|
US9000185, 4, isomer 1
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0544906
|
US9000184, 6, isomer 1
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0503711
|
US10231967, Example 73
Show/Hide
|
C25H26N4O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0483712
|
US9000185, 7, isomer 1
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0468029
|
US10231967, Example 126
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0469763
|
US9000182, 15, isomer 1
Show/Hide
|
C24H23ClN4O
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0470160
|
US9000182, 8
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0483709
|
US9000182, 13, isomer 1
Show/Hide
|
C21H26F3N3O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0518960
|
US9000185, 3
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0480069
|
US9000183, 5
Show/Hide
|
C25H24ClFN4O
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0442512
|
US9000182, 7, isomer 1
Show/Hide
|
C24H29N3O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0525228
|
US9000182, 6
Show/Hide
|
C24H29N3O
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0483714
|
US9000185, 5
Show/Hide
|
C22H27F2N3O2
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0483711
|
US9000184, 8, isomer 2
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0518959
|
US9000182, 3
Show/Hide
|
C17H20BrN3O
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0512654
|
US9000184, 7, isomer 1
Show/Hide
|
C24H27ClN4O
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0469764
|
US9000182, 14
Show/Hide
|
C21H28FN3O2
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0550126
|
US9000185, 1
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0526373
|
US9000183, 7
Show/Hide
|
C23H24ClFN4O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0484052
|
US9000184, 10, isomer 1
Show/Hide
|
C26H27ClN4O
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0525167
|
US9000184, 11, isomer 1
Show/Hide
|
C26H27ClN4O
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0468027
|
US9000183, 8
Show/Hide
|
C25H24F2N4O
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0484048
|
US9000183, 9 Isomer 1
Show/Hide
|
C25H24F2N4O
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0479350
|
US9000185, 2
Show/Hide
|
C23H29F2N3O2
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0518611
|
US9000184, 4
Show/Hide
|
C20H19ClN4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0469765
|
US9000183, 3
Show/Hide
|
C26H27ClN4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0484051
|
US9000184, 9
Show/Hide
|
C22H19ClN4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0470159
|
US9000182, 18
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0503958
|
US9000183, 2
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0469768
|
US9000184, 7, isomer 2
Show/Hide
|
C24H27ClN4O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0472325
|
US9000184, 2
Show/Hide
|
C22H19FN4
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0484049
|
US9000184, 5, isomer 1
Show/Hide
|
C19H24BrN3O
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0469767
|
US9000184, 6, isomer 2
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0484050
|
US9000184, 8, isomer 1
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0470170
|
US9000184, 10, isomer 2
Show/Hide
|
C26H27ClN4O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0550125
|
US9000182, 5, isomer 1
Show/Hide
|
C17H20BrN3O
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0526375
|
US9000184, 3
Show/Hide
|
C21H19F2N3
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0483710
|
US9000183, 4
Show/Hide
|
C18H21BrFN3O
|
1
|
| 1 |
IC50 = 176 nM
|
|
|
|
CP0470158
|
US9000182, 15, isomer 2
Show/Hide
|
C24H23ClN4O
|
1
|
| 1 |
IC50 = 216 nM
|
|
|
|
CP0539069
|
US10231967, Example 113
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 678 nM
|
|
|
|
CP0526374
|
US9000183, 6 Isomer 2
Show/Hide
|
C25H24ClFN4O
|
1
|
| 1 |
IC50 = 986 nM
|
|
|
|
CP0416734
|
N-[3-[(7-chloroquinolin-4-yl)amino]-5-(diethylaminomethyl)phenyl]-2-piperidin-1-ylacetamide
Show/Hide
|
C27H34ClN5O
|
2
|
| 1 |
IC50 = 1500 nM
|
|
|
| 2 |
IC50 = 2800 nM
|
|
|
|
CP0485467
|
N-[3-[(7-chloroquinolin-4-yl)amino]-5-[[2-(dimethylamino)ethyl-methylamino]methyl]phenyl]-2-piperidin-1-ylacetamide
Show/Hide
|
C28H37ClN6O
|
2
|
| 1 |
IC50 = 1700 nM
|
|
|
| 2 |
IC50 = 2900 nM
|
|
|
|
CP0416851
|
N-[3,5-bis(4-methylpiperazin-1-yl)phenyl]-7-chloroquinolin-4-amine
Show/Hide
|
C25H31ClN6
|
2
|
| 1 |
IC50 = 1900 nM
|
|
|
| 2 |
IC50 = 2300 nM
|
|
|
|
CP0485463
|
N-[3-[(7-chloroquinolin-4-yl)amino]-5-[[2-(dimethylamino)ethylamino]methyl]phenyl]-2-piperidin-1-ylacetamide
Show/Hide
|
C27H35ClN6O
|
2
|
| 1 |
IC50 = 2000 nM
|
|
|
| 2 |
IC50 = 2100 nM
|
|
|
|
CP0416733
|
3-N-(7-chloroquinolin-4-yl)-5-(morpholin-4-ylmethyl)-1-N-(2-piperidin-1-ylethyl)benzene-1,3-diamine
Show/Hide
|
C27H34ClN5O
|
2
|
| 1 |
IC50 = 2500 nM
|
|
|
| 2 |
IC50 = 4900 nM
|
|
|
|
CP0416768
|
N-[3-[(7-chloroquinolin-4-yl)amino]-5-(morpholin-4-ylmethyl)phenyl]-2-piperidin-1-ylacetamide
Show/Hide
|
C27H32ClN5O2
|
2
|
| 1 |
IC50 = 3100 nM
|
|
|
| 2 |
IC50 = 7100 nM
|
|
|
|
CP0066164
|
4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol
Show/Hide
|
C20H22ClN3O
|
2
|
| 1 |
IC50 = 4000 nM
|
|
|
| 2 |
IC50 = 5400 nM
|
|
|
|
CP0416769
|
1-N,3-N-bis(2-piperidin-1-ylethyl)-5-[2-(piperidin-1-ylmethyl)anilino]benzene-1,3-dicarboxamide
Show/Hide
|
C34H50N6O2
|
2
|
| 1 |
IC50 = 4100 nM
|
|
|
| 2 |
IC50 = 4700 nM
|
|
|
|
CP0477921
|
7-chloro-N-[3-(diethylaminomethyl)phenyl]quinolin-4-amine
Show/Hide
|
C20H22ClN3
|
2
|
| 1 |
IC50 = 4500 nM
|
|
|
| 2 |
IC50 = 10400 nM
|
|
|
|
CP0456319
|
3,5-bis[(2-piperidin-1-ylethylamino)methyl]-N-[2-(piperidin-1-ylmethyl)phenyl]aniline
Show/Hide
|
C34H54N6
|
2
|
| 1 |
IC50 = 4600 nM
|
|
|
| 2 |
IC50 = 6000 nM
|
|
|
|
CP0387372
|
4-[(7-chloroquinolin-4-yl)amino]-2,6-bis(pyrrolidin-1-ylmethyl)phenol
Show/Hide
|
C25H29ClN4O
|
2
|
| 1 |
IC50 = 5100 nM
|
|
|
| 2 |
IC50 = 11200 nM
|
|
|
|
CP0416766
|
1-N,3-N-bis(2-piperidin-1-ylethyl)-5-[2-(piperidin-1-ylmethyl)phenyl]benzene-1,3-dicarboxamide
Show/Hide
|
C34H49N5O2
|
2
|
| 1 |
IC50 = 6200 nM
|
|
|
| 2 |
IC50 = 9400 nM
|
|
|
|
CP0393465
|
N-[2-(morpholin-4-ylmethyl)phenyl]-3,5-bis[(2-piperidin-1-ylethylamino)methyl]aniline
Show/Hide
|
C33H52N6O
|
2
|
| 1 |
IC50 = 6600 nM
|
|
|
| 2 |
IC50 = 7900 nM
|
|
|
|
CP0029912
|
Aralen
Show/Hide
|
C18H26ClN3
|
2
|
| 1 |
IC50 = 7000 nM
|
|
|
| 2 |
IC50 = 12800 nM
|
|
|
|
CP0477922
|
5-[2-[(dimethylamino)methyl]anilino]-1-N,3-N-bis(2-piperidin-1-ylethyl)benzene-1,3-dicarboxamide
Show/Hide
|
C31H46N6O2
|
2
|
| 1 |
IC50 = 8200 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0393467
|
3-N-(7-chloroquinolin-4-yl)-5-(diethylaminomethyl)-1-N-(2-piperidin-1-ylethyl)benzene-1,3-diamine
Show/Hide
|
C27H36ClN5
|
2
|
| 1 |
IC50 = 10000 nM
|
|
|
| 2 |
IC50 = 13800 nM
|
|
|
|
CP0477920
|
5-[2-[(dimethylamino)methyl]phenyl]-1-N,3-N-bis(2-piperidin-1-ylethyl)benzene-1,3-dicarboxamide
Show/Hide
|
C31H45N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0485464
|
5-[2-[(4-methylpiperazin-1-yl)methyl]phenyl]-1-N,3-N-bis(2-piperidin-1-ylethyl)benzene-1,3-dicarboxamide
Show/Hide
|
C34H50N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0485465
|
N-[[3-[2-[(dimethylamino)methyl]phenyl]-5-[(2-piperidin-1-ylethylamino)methyl]phenyl]methyl]-2-piperidin-1-ylethanamine
Show/Hide
|
C31H49N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0416735
|
5-[2-(morpholin-4-ylmethyl)anilino]-1-N,3-N-bis(2-piperidin-1-ylethyl)benzene-1,3-dicarboxamide
Show/Hide
|
C33H48N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0416737
|
N-[2-[(4-methylpiperazin-1-yl)methyl]phenyl]-3,5-bis[(2-piperidin-1-ylethylamino)methyl]aniline
Show/Hide
|
C34H55N7
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0416738
|
5-[2-(morpholin-4-ylmethyl)phenyl]-1-N,3-N-bis(2-piperidin-1-ylethyl)benzene-1,3-dicarboxamide
Show/Hide
|
C33H47N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0477923
|
N-[[3-[2-(morpholin-4-ylmethyl)phenyl]-5-[(2-piperidin-1-ylethylamino)methyl]phenyl]methyl]-2-piperidin-1-ylethanamine
Show/Hide
|
C33H51N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0485468
|
N-[[3-[2-[(4-methylpiperazin-1-yl)methyl]phenyl]-5-[(2-piperidin-1-ylethylamino)methyl]phenyl]methyl]-2-piperidin-1-ylethanamine
Show/Hide
|
C34H54N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0517725
|
2-piperidin-1-yl-N-[[3-[(2-piperidin-1-ylethylamino)methyl]-5-[2-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]ethanamine
Show/Hide
|
C34H53N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0538714
|
5-[2-[(4-methylpiperazin-1-yl)methyl]anilino]-1-N,3-N-bis(2-piperidin-1-ylethyl)benzene-1,3-dicarboxamide
Show/Hide
|
C34H51N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0550425
|
N-[2-[(dimethylamino)methyl]phenyl]-3,5-bis[(2-piperidin-1-ylethylamino)methyl]aniline
Show/Hide
|
C31H50N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
