Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9000182, 14
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Canonical SMILES
CO[C@H]1CC[C@@]2(Cc3ccc(OCC(C)F)cc3C22N=C(C)C(N)=N2)CC1
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Compound Formula C21H28FN3O2
Compound Structure
Protein Name
 Protein Info 
Amyloid-beta precursor protein
Protein Classification
Membrane receptor
Uniprot ID
P05067
Gene Name
APP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.5 nM
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