Brief Information of the Compound and Protein
Compound Name
1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-pyrazin-2-ylsulfonylurea
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PubChem ID
CID: 137403460
Canonical SMILES
O=C(Nc1c2CCCc2cc2CCCc12)NS(=O)(=O)c1cnccn1
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Compound Formula C17H18N4O3S
Compound Structure
Protein Name
NACHT, LRR and PYD domains-containing protein 3
Protein Classification
Unclassified protein
Uniprot ID
Q96P20
Gene Name
NLRP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 960 nM
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