Brief Information of the Compound and Protein
Compound Name
(5R)-4-[2-[(2S)-2-(4-chlorophenyl)-3-(propan-2-ylamino)propanoyl]-2,6-diazaspiro[3.3]heptan-6-yl]-5-methyl-6,8-dihydro-5H-pyrido[2,3-d]pyrimidin-7-one
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Canonical SMILES
CC(C)NC[C@@H](C(=O)N1CC2(C1)CN(C2)c1ncnc2NC(=O)C[C@@H](C)c12)c1ccc(Cl)cc1
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Compound Formula C25H31ClN6O2
Compound Structure
Protein Name
RAC-gamma serine/threonine-protein kinase
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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AGC protein kinase group
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AGC protein kinase AKT family
Uniprot ID
Q9Y243
Gene Name
AKT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 953 nM
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