Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-((4-(6-((4-Chloro-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-3-methyl-3H-imidazo[4,5-b]pyridine-5-carboxylic acid
    Show/Hide
 PubChem ID
CID: 134611229
Canonical SMILES
Cn1c(CN2CCC(CC2)c2cccc(OCc3ccc(Cl)cc3F)n2)nc2ccc(nc12)C(O)=O
    Show/Hide
Compound Formula C26H25ClFN5O3
Compound Structure
Protein Name
 Protein Info 
Glucagon-like peptide 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
>
Glucagon-like peptide receptor
Uniprot ID
P43220
Gene Name
GLP1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 6.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 95 nM
   TI
   LI
   LO
   TS
CL001038 PathHunter CHO-K1 GLP1R beta-arrestin-2
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 2800 nM
   TI
   LI
   LO
   TS
2
EC50 > 30000 nM
   TI
   LI
   LO
   TS