Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[2-[[4-[6-[(4-chloro-2-fluorophenyl)methoxy]pyridin-2-yl]piperidin-1-yl]methyl]-1-methylimidazo[4,5-b]pyridin-7-yl]amino]acetic acid
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 PubChem ID
CID: 168294984
Canonical SMILES
Cn1c(CN2CCC(CC2)c2cccc(OCc3ccc(Cl)cc3F)n2)nc2nccc(NCC(O)=O)c12
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Compound Formula C27H28ClFN6O3
Compound Structure
Protein Name
 Protein Info 
Glucagon-like peptide 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
>
Glucagon-like peptide receptor
Uniprot ID
P43220
Gene Name
GLP1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 > 20000 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 44 nM
   TI
   LI
   LO
   TS
2
EC50 = 4600 nM
   TI
   LI
   LO
   TS
CL001038 PathHunter CHO-K1 GLP1R beta-arrestin-2
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 1500 nM
   TI
   LI
   LO
   TS
2
EC50 > 30000 nM
   TI
   LI
   LO
   TS