Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(4-{6-[(2,4-difluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(1-ethyl-1H-imidazol-5-yl)methyl]-1H-benzimidazole-6-carboxylic acid
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 PubChem ID
CID: 134611223
Canonical SMILES
CCn1cncc1Cn1c(CN2CCC(CC2)c2cccc(OCc3ccc(F)cc3F)n2)nc2ccc(cc12)C(O)=O
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Compound Formula C32H32F2N6O3
Compound Structure
Protein Name
 Protein Info 
Glucagon-like peptide 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
>
Glucagon-like peptide receptor
Uniprot ID
P43220
Gene Name
GLP1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 8.6 nM
   TI
   LI
   LO
   TS
2
Ki = 51 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.75 nM
   TI
   LI
   LO
   TS
CL000609 PathHunter CHO-K1 GLP1R beta-arrestin-1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 250 nM
   TI
   LI
   LO
   TS
CL001038 PathHunter CHO-K1 GLP1R beta-arrestin-2
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 610 nM
   TI
   LI
   LO
   TS