Brief Information of the Compound and Protein
Compound Name
N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-methylpiperazin-1-yl)phenyl]prop-2-enamide
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PubChem ID
CID: 146271387
Canonical SMILES
COc1cc(OC)cc(c1)C(=O)c1c[nH]c2nc(Nc3ccc(cc3NC(=O)C=C)N3CCN(C)CC3)ccc12
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Compound Formula C30H32N6O4
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
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Kinase
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Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 < 1.5 nM
   TI
   LI
   LO
   TS