Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino]-3-methylphenyl]prop-2-enamide
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 PubChem ID
CID: 72710839
Canonical SMILES
COc1cc(OC)c(Cl)c(c1Cl)-c1ccc2nc(Nc3c(C)cccc3NC(=O)C=C)ncc2c1
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Compound Formula C26H22Cl2N4O3
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22455
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  4
1
IC50 = 9.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 11 nM
   TI
   LI
   LO
   TS
3
IC50 = 14 nM
   TI
   LI
   LO
   TS
4
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.16 nM
2 IC50 = 1.78 nM
3 IC50 = 3 nM
4 IC50 = 6.3 nM
5 IC50 = 14 nM
6 IC50 = 2324 nM