Brief Information of the Compound and Protein
Compound Name
N-[4-[[2-[4-chloro-2-(1,1-difluoroethyl)phenyl]-6H-thieno[2,3-e]indazol-3-yl]oxy]phenyl]-1-(3-fluoropropyl)azetidin-3-amine
    Show/Hide
PubChem ID
CID: 168286374
Canonical SMILES
CC(F)(F)c1cc(Cl)ccc1-c1sc2c(ccc3[nH]ncc23)c1Oc1ccc(NC2CN(CCCF)C2)cc1
    Show/Hide
Compound Formula C29H26ClF3N4OS
Compound Structure
Protein Name
Estrogen receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
>
Nuclear hormone receptor subfamily 3 group A member 2
Uniprot ID
Q92731
Gene Name
ESR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001042 HEK293/Gal4 Homo sapiens (Human)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS