Brief Information of the Compound and Protein
Compound Name
2-[4-chloro-2-(1,1-difluoroethyl)phenyl]-3-[4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-6H-thieno[2,3-e]indazole
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PubChem ID
CID: 168278867
Canonical SMILES
CC(F)(F)c1cc(Cl)ccc1-c1sc2c(ccc3[nH]ncc23)c1Oc1ccc(OC2CN(CCCF)C2)cc1
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Compound Formula C29H25ClF3N3O2S
Compound Structure
Protein Name
Estrogen receptor beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 2
Uniprot ID
Q92731
Gene Name
ESR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001042 HEK293/Gal4 Homo sapiens (Human)  1
1
IC50 = 2.3 nM
   TI
   LI
   LO
   TS